LOCUS HUMC1R 2493 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human complement C1r mRNA, complete cds.
ACCESSION M14058
VERSION M14058.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2493)
AUTHORS Leytus,S.P., Kurachi,K., Sakariassen,K.S. and Davie,E.W.
TITLE Nucleotide sequence of the cDNA coding for human complement C1r
JOURNAL Biochemistry 25 (17), 4855-4863 (1986)
PUBMED 3021205
COMMENT Original source text: Human, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2493
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12p13"
gene 1..2493
/gene="C1R"
CDS 64..2181
/gene="C1R"
/note="human complement C1r"
/codon_start=1
/protein_id="AAA51851.1"
/db_xref="GDB:G00-119-729"
/translation="MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFET
TTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGK
KEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQ
CQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEASGYISSLEYPRSYPPDL
RCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDL
DTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYF
IATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTT
MGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPV
CGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKE
HEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENS
VTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWL
RGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSR
GYGFYTKVLNYVDWIKKEMEEED"
mat_peptide 64..1452
/gene="C1R"
/product="C1r A chain"
mat_peptide 1453..2178
/gene="C1R"
/product="C1r B chain serine protease"
BASE COUNT 619 a 680 c 662 g 532 t
ORIGIN Chromosome 12p13.
1 ggatcgattt gagtaagagc atagctgtcg ggagagccca ggattcaaca cgggccttga
61 gaaatgtggc tcttgtacct cctggtgccg gccctgttct gcagggcagg aggctccatt
121 cccatccctc agaagttatt tggggaggtg acttcccctc tgttccccaa gccttacccc
181 aacaactttg aaacaaccac tgtgatcaca gtccccacgg gatacagggt gaagctcgtc
241 ttccagcagt ttgacctgga gccttctgaa ggctgcttct atgattatgt caagatctct
301 gctgataaga aaagcctggg gaggttctgt gggcaactgg gttctccact gggcaacccc
361 ccgggaaaga aggaatttat gtcccaaggg aacaagatgc tgctgacctt ccacacagac
421 ttctccaacg aggagaatgg gaccatcatg ttctacaagg gcttcctggc ctactaccaa
481 gctgtggacc ttgatgaatg tgcttcccgg agcaaatcag gggaggagga tccccagccc
541 cagtgccagc acctgtgtca caactacgtt ggaggctact tctgttcctg ccgtccaggc
601 tatgagcttc aggaagacag gcattcctgc caggctgagt gcagcagcga gctgtacacg
661 gaggcatcag gctacatctc cagcctggag taccctcggt cctacccccc tgacctgcgc
721 tgcaactaca gcatccgggt ggagcggggc ctcaccctgc acctcaagtt cctggagcct
781 tttgatattg atgaccacca gcaagtacac tgcccctatg accagctaca gatctatgcc
841 aacgggaaga acattggcga gttctgtggg aagcaaaggc cccccgacct cgacaccagc
901 agcaatgctg tggatctgct gttcttcaca gatgagtcgg gggacagccg gggctggaag
961 ctgcgctaca ccaccgagat catcaagtgc ccccagccca agaccctaga cgagttcacc
1021 atcatccaga acctgcagcc tcagtaccag ttccgtgact acttcattgc tacctgcaag
1081 caaggctacc agctcataga ggggaaccag gtgctgcatt ccttcacagc tgtctgccag
1141 gatgatggca cgtggcatcg tgccatgccc agatgcaaga tcaaggactg tgggcagccc
1201 cgaaacctgc ctaatggtga cttccgttac accaccacaa tgggagtgaa cacctacaag
1261 gcccgtatcc agtactactg ccatgagcca tattacaaga tgcagaccag agctggcagc
1321 agggagtctg agcaaggggt gtacacctgc acagcacagg gcatttggaa gaatgaacag
1381 aagggagaga agattcctcg gtgcttgcca gtgtgtggga agcccgtgaa ccccgtggaa
1441 cagaggcagc gcataatcgg agggcaaaaa gccaagatgg gcaacttccc ctggcaggtg
1501 ttcaccaaca tccacgggcg cgggggcggg gccctgctgg gcgaccgctg gatcctcaca
1561 gctgcccaca ccctgtatcc caaggaacac gaagcgcaaa gcaacgcctc tttggatgtg
1621 ttcctgggcc acacaaatgt ggaagagctc atgaagctag gaaatcaccc catccgcagg
1681 gtcagcgtcc acccggacta ccgtcaggat gagtcctaca attttgaggg ggacatcgcc
1741 ctgctggagc tggaaaatag tgtcaccctg ggtcccaacc tcctccccat ctgcctccct
1801 gacaacgata ccttctacga cctgggcttg atgggctatg tcagtggctt cggggtcatg
1861 gaggagaaga ttgctcatga cctcaggttt gtccgtctgc ccgtagctaa tccacaggcc
1921 tgtgagaact ggctccgggg aaagaatagg atggatgtgt tctctcaaaa catgttctgt
1981 gctggacacc catctctaaa gcaggacgcc tgccaggggg atagtggggg cgtttttgca
2041 gtaagggacc cgaacactga tcgctgggtg gccacgggca tcgtgtcctg gggcatcggg
2101 tgcagcaggg gctatggctt ctacaccaaa gtgctcaact acgtggactg gatcaagaaa
2161 gagatggagg aggaggactg agcccagaat tcactaggtt cgaatccaga gagcagtgtg
2221 gaaaaaaaaa aaacaaaaaa caactgacca gttgttgata accactaaga gtctctatta
2281 aaattactga tgcagaaaga ccgtgtgtga aattctcttt cctgtagtcc cattgatgta
2341 ctttacctga aacaacccaa aggccccttt ctttcttctg aggattgcag aggatatagt
2401 tatcaatctc tagttgtcac tttcctcttc cactttgata ccattgggtc attgaatata
2461 actttttcca aataaagttt tatgagaaat gcc
//