LOCUS HUMPKB 2955 bp mRNA linear HUM 12-AUG-1999
DEFINITION Homo sapiens protein kinase C beta-II type (PRKCB1) mRNA, complete
cds.
ACCESSION M13975
VERSION M13975.1
KEYWORDS protein kinase C-beta-1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2955)
AUTHORS Coussens,L., Parker,P.J., Rhee,L., Yang-Feng,T.L., Chen,E.,
Waterfield,M.D., Francke,U. and Ullrich,A.
TITLE Multiple, distinct forms of bovine and human protein kinase C
suggest diversity in cellular signaling pathways
JOURNAL Science 233 (4766), 859-866 (1986)
PUBMED 3755548
FEATURES Location/Qualifiers
source 1..2955
/db_xref="H-InvDB:HIT000194283"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="16p12"
/clone="lambda-hPKC-beta15-802"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..2955
/gene="PRKCB1"
CDS 65..2086
/gene="PRKCB1"
/codon_start=1
/product="protein kinase C beta-II type"
/protein_id="AAA60095.1"
/translation="MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFF
KQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKH
KFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRG
RIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCS
LNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFK
LLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNR
DRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKR
VLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI
AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYI
APEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSK
EAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR
NAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEVKS"
BASE COUNT 773 a 725 c 719 g 738 t
ORIGIN
1 cgcagcccgc ggtcccgccg ccccggggcc ggcacctctc gggctccggc tccccgcgcg
61 caagatggct gacccggctg cggggccgcc gccgagcgag ggcgaggaga gcaccgtgcg
121 cttcgcccgc aaaggcgccc tcaggcagaa gaacgtgcat gaggtcaaga accacaaatt
181 caccgcccgc ttcttcaagc agcccacctt ctgcagccac tgcaccgact tcatctgggg
241 cttcgggaag cagggattcc agtgccaagt ttgctgcttt gtggtgcaca agcggtgcca
301 tgaatttgtc acattctcct gccctggcgc tgacaagggt ccagcctccg atgacccccg
361 cagcaaacac aagtttaaga tccacacgta ctccagcccc acgttttgtg accactgtgg
421 gtcactgctg tatggactca tccaccaggg gatgaaatgt gacacctgca tgatgaacgt
481 gcacaagcgc tgcgtgatga atgttcccag cctgtgtggc acggaccaca cggagcgccg
541 cggccgcatc tacatccagg cccacatcga cagggacgtc ctcattgtcc tcgtaagaga
601 tgctaaaaac cttgtaccta tggaccccaa tggcctgtca gatccctacg taaaactgaa
661 actgattccc gatcccaaaa gtgagagcaa acagaagacc aaaaccatca aatgctccct
721 caaccctgag tggaatgaga catttagatt tcagctgaaa gaatcggaca aagacagaag
781 actgtcagta gagatttggg attgggattt gaccagcagg aatgacttca tgggatcttt
841 gtcctttggg atttctgaac ttcagaaagc cagtgttgat ggctggttta agttactgag
901 ccaggaggaa ggcgagtact tcaatgtgcc tgtgccacca gaaggaagtg aggccaatga
961 agaactgcgg cagaaatttg agagggccaa gatcagtcag ggaaccaagg tcccggaaga
1021 aaagacgacc aacactgtct ccaaatttga caacaatggc aacagagacc ggatgaaact
1081 gaccgatttt aacttcctaa tggtgctggg gaaaggcagc tttggcaagg tcatgctttc
1141 agaacgaaaa ggcacagatg agctctatgc tgtgaagatc ctgaagaagg acgttgtgat
1201 ccaagatgat gacgtggagt gcactatggt ggagaagcgg gtgttggccc tgcccgggaa
1261 gccgcccttc ctgacccagc tccactcctg cttccagacc atggaccgcc tgtactttgt
1321 gatggagtac gtgaatgggg gcgacctcat gtatcacatc cagcaagtcg gccggttcaa
1381 ggagccccat gctgtatttt acgctgcaga aattgccatc ggtctgttct tcttacagag
1441 taagggcatc atttaccgtg acctaaaact tgacaacgtg atgctcgatt ctgagggaca
1501 catcaagatt gccgattttg gcatgtgtaa ggaaaacatc tgggatgggg tgacaaccaa
1561 gacattctgt ggcactccag actacatcgc ccccgagata attgcttatc agccctatgg
1621 gaagtccgtg gattggtggg catttggagt cctgctgtat gaaatgttgg ctgggcaggc
1681 accctttgaa ggggaggatg aggatgaact cttccaatcc atcatggaac acaacgtagc
1741 ctatcccaag tctatgtcca aggaagctgt ggccatctgc aaagggctga tgaccaaaca
1801 cccaggcaaa cgtctgggtt gtggacctga aggtgaacgt gatatcaaag agcatgcatt
1861 tttccggtat attgattggg agaaacttga acgcaaagag attcagcccc cttataagcc
1921 aaaagcttgt gggcgaaatg ctgaaaactt cgaccgattt ttcacccgcc atccaccagt
1981 cctaacacct cctgaccagg aagtcatcag gaatattgac caatcagaat tcgaaggatt
2041 ttcctttgtt aactctgaat ttttaaaacc cgaagtcaag agctaagtag atgtgtagat
2101 ctccgtcctt catttctgtc attcaagctc aacggctatt gtggtgacat ttttatgttt
2161 tcattgccaa gttgcatcca tgtttgattt tctgatgaga ctagagtgac agtgtttcag
2221 aacccaaatg tcctcaggta gttttggagc atctctatga gatgggatta tgcagatggc
2281 ctatggaaaa tgcagctgca taattaacac attatcaaag tcctcttaca atttattttc
2341 cgcagcatgt cagctaagta gacccaatgg ggagagaaaa tgcctgcttt ctttcccttt
2401 tttctgcact gccatattca cccccaacca tccaatctgt ggataattgg atgttagcgg
2461 tactcttcca cttccgggcc tggagcttgg cttgtatcca agtgtatggt tgctttgcct
2521 aagaggaatc cctctatttc acctgttctg gaggcaccag accttgaaaa gaacatgctc
2581 aaaataaaat gttatctgtt atttttgtaa actcaaagtt aagatgatca aagttctaaa
2641 attccaagaa tgtgctttta gacggtctca atctaaaagc acttcaaggg gtcaaagggc
2701 aaccagcttg ggtgctacct cagtgttgta gtttctgata ctttatgtct ttgctcaccc
2761 tcatccccaa actacttgaa aagggcattt ggcaccactc tctgaaacaa cacagtcact
2821 ctagcaaggc ccccaaaggg ccctggtttt acattacatt tcaaacttta tttgctttgg
2881 ggttttgttt ctgttgttgt tcaaatgcaa aaaaaaatta tttgctttgg ggttttattt
2941 ctgttgttca aatgc
//