LOCUS HUMCMYBA 2977 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human c-myb mRNA, 3'end.
ACCESSION M13665
VERSION M13665.1
KEYWORDS c-myc proto-oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2977)
AUTHORS Slamon,D.J., Boone,T.C., Murdock,D.C., Keith,D.E., Press,M.F.,
Larson,R.A. and Souza,L.M.
TITLE Studies of the human c-myb gene and its product in human acute
leukemias
JOURNAL Science 233 (4761), 347-351 (1986)
PUBMED 3014652
COMMENT Original source text: Human acute myelogenous leukemia blast cell,
cDNA to mRNA, clone h-myb7.
FEATURES Location/Qualifiers
source 1..2977
/db_xref="H-InvDB:HIT000194234"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="6q22-q23"
gene 1..2977
/gene="MYB"
CDS <1..1785
/gene="MYB"
/note="c-myb protein"
/codon_start=1
/protein_id="AAA52030.1"
/db_xref="GDB:G00-119-441"
/translation="EDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPEL
IKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWT
EEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKAS
QPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVA
LHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTC
SYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIVHQG
TILDNVKNLLEFAETLQFIDSFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRD
QTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVE
DLQDVIKQESDESGIVAEFQENGPPLLKKIKQEVESPTDKSGNFFCSHHWEGDSLNTQ
LFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAFTVPKNRSLASPLQPCSSTWEPAS
CGKMEEQMTSSSQARKYVNAFSARTLVM"
BASE COUNT 929 a 612 c 603 g 833 t
ORIGIN Chromosome 6q22-q23.
1 gaggatgaaa aactgaagaa gctggtggaa cagaatggaa cagatgactg gaaagttatt
61 gccaattatc tcccgaatcg aacagatgtg cagtgccagc accgatggca gaaagtacta
121 aaccctgagc tcatcaaggg tccttggacc aaagaagaag atcagagagt gatagagctt
181 gtacagaaat acggtccgaa acgttggtct gttattgcca agcacttaaa ggggagaatt
241 ggaaaacaat gtagggagag gtggcataac cacttgaatc cagaagttaa gaaaacctcc
301 tggacagaag aggaagacag aattatttac caggcacaca agagactggg gaacagatgg
361 gcagaaatcg caaagctact gcctggacga actgataatg ctatcaagaa ccactggaat
421 tctacaatgc gtcggaaggt cgaacaggaa ggttatctgc aggagtcttc aaaagccagc
481 cagccagcag tggccacaag cttccagaag aacagtcatt tgatgggttt tgctcaggct
541 ccgcctacag ctcaactccc tgccactggc cagcccactg ttaacaacga ctattcctat
601 taccacattt ctgaagcaca aaatgtctcc agtcatgttc cataccctgt agcgttacat
661 gtaaatatag tcaatgtccc tcagccagct gccgcagcca ttcagagaca ctataatgat
721 gaagaccctg agaaggaaaa gcgaataaag gaattagaat tgctcctaat gtcaaccgag
781 aatgagctaa aaggacagca ggtgctacca acacagaacc acacatgcag ctaccccggg
841 tggcacagca ccaccattgc cgaccacacc agacctcatg gagacagtgc acctgtttcc
901 tgtttgggag aacaccactc cactccatct ctgccagcgg atcctggctc cctacctgaa
961 gaaagcgcct cgccagcaag gtgcatgatc gtccaccagg gcaccattct ggataatgtt
1021 aagaacctct tagaatttgc agaaacactc caatttatag attctttctt aaacacttcc
1081 agtaaccatg aaaactcaga cttggaaatg ccttctttaa cttccacccc cctcattggt
1141 cacaaattga ctgttacaac accatttcat agagaccaga ctgtgaaaac tcaaaaggaa
1201 aatactgttt ttagaacccc agctatcaaa aggtcaatct tagaaagctc tccaagaact
1261 cctacaccat tcaaacatgc acttgcagct caagaaatta aatacggtcc cctgaagatg
1321 ctacctcaga caccctctca tctagtagaa gatctgcagg atgtgatcaa acaggaatct
1381 gatgaatctg gaattgttgc tgagtttcaa gaaaatggac cacccttact gaagaaaatc
1441 aaacaagagg tggaatctcc aactgataaa tcaggaaact tcttctgctc acaccactgg
1501 gaaggggaca gtctgaatac ccaactgttc acgcagacct cgcctgtggc agatgcaccg
1561 aatattctta caagctccgt tttaatggca ccagcatcag aagatgaaga caatgttctc
1621 aaagcattta cagtacctaa aaacaggtcc ctggcgagcc ccttgcagcc ttgtagcagt
1681 acctgggaac ctgcatcctg tggaaagatg gaggagcaga tgacatcttc cagtcaagct
1741 cgtaaatacg tgaatgcatt ctcagcccgg acgctggtca tgtgagacat ttccagaaaa
1801 gcattatggt tttcagaaca cttcaagttg acttgggata tatcattcct caacatgaaa
1861 cttttcatga atgggagaag aacctatttt tgttgtggta caacagttga gagcagcacc
1921 aagtgcattt agttgaatga agtcttcttg gatttcaccc aactaaaagg atttttaaaa
1981 ataaataaca gtcttaccta aattattagg taatgaattg tagccagttg ttaatatctt
2041 aatgcagatt tttttaaaaa aaaacataaa atgatttatc tgtattttaa aggatccaac
2101 agatcagtat tttttcctgt gatgggtttt ttgaaatttg acacattaaa aggtactcca
2161 gtatttcact tttctcgatc actaaacata tgcatatatt tttaaaaatc agtaaaagca
2221 ttactctaag tgtagactta ataccatgtg acatttaatc cagattgtaa atgctcattt
2281 atggttaatg acattgaagg tacatttatt gtaccaaacc attttatgag ttttctgtta
2341 gcttgcttta aaaattatta ctgtaagaaa tagttttata aaaaattata tttttattca
2401 gtaatttaat tttgtaaatg ccaaatgaaa aacgtttttt gctgctatgg tcttagcctg
2461 tagacatgct gctagtatca gaggggcagt agagcttgga cagaaagaaa agaaacttgg
2521 tgttaggtaa ttgactatgc actagtattt cagacttttt aattttatat atatatacat
2581 tttttttcct tctgcaatac atttgaaaac ttgtttggga gactctgcat tttttattgt
2641 ggtttttttg ttattgttgg tttatacaag catgcgttgc acttcttttt tgggagatgt
2701 gtgttgttga tgttctatgt tttgttttga gtgtagcctg actgttttat aatttgggag
2761 ttctgcattt gatccgcatc ccctgtggtt tctaagtgta tggtctcaga actgttgcat
2821 ggatcctgtg tttgcaactg gggagacaga aactgtggtt gatagccagt cactgcctta
2881 agaacatttg atgcaagatg gccagcactg aacttttgag atatgacggt gtacttactg
2941 ccttgtagca aaataaagat gtgcccttat tttacct
//