LOCUS HUMMAS 1388 bp mRNA linear HUM 11-JUN-1993
DEFINITION Human mas proto-oncogene mRNA, complete cds.
ACCESSION M13150
VERSION M13150.1
KEYWORDS mas oncogene; mas protein; membrane protein; proto-oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1388)
AUTHORS Young,D., Waitches,G., Birchmeier,C., Fasano,O. and Wigler,M.
TITLE Isolation and characterization of a new cellular oncogene encoding
a protein with multiple potential transmembrane domains
JOURNAL Cell 45 (5), 711-719 (1986)
PUBMED 3708691
COMMENT Original source text: Human, cDNA to mRNA, clone pMS424; and DNA,
clone pMS422.
Draft entry and sequence in computer-readable form for [1] kindly
provided by D.Young, 11-DEC-1986.
The mas oncogene has a weak focus-inducing activity in transfected
NIH 3T3 cells. A DNA rearrangement, which occurrs during
transfection, is probably responsible for activation of the mas
gene. The mas gene may be the first of a new functional class of
oncogenes.
The first 253 nucleotides are from DNA and the rest from cDNA.
FEATURES Location/Qualifiers
source 1..1388
/db_xref="H-InvDB:HIT000194206"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..>1388
/product="mas mRNA"
CDS 268..1245
/note="mas protein"
/codon_start=1
/protein_id="AAA36199.1"
/translation="MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISP
VGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHY
YTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALS
CLVTTMEYVMCIDREEESHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNT
WASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSAN
PFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV"
BASE COUNT 346 a 329 c 284 g 429 t
ORIGIN 1032 bp upstream of SalI site.
1 ggatccagaa gggtcattca atcagttctc agtcttatca ggtctaagtt cctttcttat
61 caggtcctaa aggcctaatc ttatcattgt gacaaagata actgtagagt ctgttaaact
121 ttttttttaa taacatgaag attatgattt atagctgaat ttctcccttt tattccaatt
181 caacaatttt catggctttt tgtgtttgtt ttgttctgga catatttaca gaaaattacc
241 tgaagagttc caacctgagg cctcctcatg gatgggtcaa acgtgacatc atttgttgtt
301 gaggaaccca cgaacatctc aactggcagg aacgcctcag tcgggaatgc acatcggcaa
361 atccccatcg tgcactgggt cattatgagc atctccccag tggggtttgt tgagaatggg
421 attctcctct ggttcctgtg cttccggatg agaagaaatc ccttcactgt ctacatcacc
481 cacctgtcta tcgcagacat ctcactgctc ttctgtattt tcatcttgtc tatcgactat
541 gctttagatt atgagctttc ttctggccat tactacacaa ttgtcacatt atcagtgact
601 tttctgtttg gctacaacac gggcctctat ctgctgacgg ccattagtgt ggagaggtgc
661 ctgtcagtcc tttaccccat ctggtaccga tgccatcgcc ccaagtacca gtcggcattg
721 gtctgtgccc ttctgtgggc tctttcttgc ttggtgacca ccatggagta tgtcatgtgc
781 atcgacagag aagaagagag tcactctcgg aatgactgcc gagcagtcat catctttata
841 gccatcctga gcttcctggt cttcacgccc ctcatgctgg tgtccagcac catcttggtc
901 gtgaagatcc ggaagaacac gtgggcttcc cattcctcca agctttacat agtcatcatg
961 gtcaccatca ttatattcct catcttcgct atgcccatga gactccttta cctgctgtac
1021 tatgagtatt ggtcgacctt tgggaaccta caccacattt ccctgctctt ctccacaatc
1081 aacagtagcg ccaacccttt catttacttc tttgtgggaa gcagtaagaa gaagagattc
1141 aaggagtcct taaaagttgt tctgaccagg gctttcaaag atgaaatgca acctcggcgc
1201 cagaaagaca attgtaatac ggtcacagtt gagactgtcg tctaagaact gtgagggaag
1261 ttgtggataa aaatggtgga acacaggtca tttttagttt gtgcttggaa tatgacttaa
1321 gtatctccta aatgtgatac agaagaacat ctcatcccat atgcatgaga tactaattaa
1381 tgatgaaa
//