LOCUS HUMCRPGA 2480 bp DNA linear HUM 01-NOV-1994
DEFINITION Human C-reactive protein gene, complete cds.
ACCESSION M11725
VERSION M11725.1
KEYWORDS C-reactive protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2480)
AUTHORS Lei,K.J., Liu,T., Zon,G., Soravia,E., Liu,T.Y. and Goldman,N.D.
TITLE Genomic DNA sequence for human C-reactive protein
JOURNAL J. Biol. Chem. 260 (24), 13377-13383 (1985)
PUBMED 2997165
COMMENT Original source text: Human fetus liver DNA.
FEATURES Location/Qualifiers
source 1..2480
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/map="1q21-q23"
CDS join(230..290,569..1182)
/note="C-reactive protein"
/codon_start=1
/protein_id="AAA52075.1"
/translation="MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPL
TKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILF
EVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSF
GGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFT
KPQLWP"
gene 230..290
/gene="CRP"
exon <230..290
/gene="CRP"
/note="C-reactive protein; G00-119-071"
/number=1
intron 291..568
/note="intron A"
exon 569..>1182
/note="C-reactive protein"
/number=2
BASE COUNT 621 a 574 c 620 g 665 t
ORIGIN Chromosome 1q12-q23.
1 tttgcttccc ctcttcccga agctctgaca cctgccccaa caagcaatgt tggaaaatta
61 tttacatagt ggcgcaaact cccttactgc tttggatata aatccaggca ggaggaggta
121 gctctaaggc aagagatctg ggacttctag cccctgaact ttcagccgaa tacatctttt
181 ccaaaggagt gaattcaggc ccttgtatca ctggcagcag gacgtgacca tggagaagct
241 gttgtgtttc ttggtcttga ccagcctctc tcatgctttt ggccagacag gtaagggcca
301 ccccaggcta tgggagagtt ttgatctgag gtatgggggt ggggtctaag actgcatgaa
361 cagtctcaaa aaaaaaaaaa aaagactgta tgaacagaac agtggagcat ccttcatggt
421 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgg tgtgtaactg gagaaggggt cagtctgttt
481 ctcaatctta aattctatac gtaagtgagg ggatagatct gtgtgatctg agaaacctct
541 cacatttgct tgtttttctg gctcacagac atgtcgagga aggcttttgt gtttcccaaa
601 gagtcggata cttcctatgt atccctcaaa gcaccgttaa cgaagcctct caaagccttc
661 actgtgtgcc tccacttcta cacggaactg tcctcgaccc gtgggtacag tattttctcg
721 tatgccacca agagacaaga caatgagatt ctcatatttt ggtctaagga tataggatac
781 agttttacag tgggtgggtc tgaaatatta ttcgaggttc ctgaagtcac agtagctcca
841 gtacacattt gtacaagctg ggagtccgcc tcagggatcg tggagttctg ggtagatggg
901 aagcccaggg tgaggaagag tctgaagaag ggatacactg tgggggcaga agcaagcatc
961 atcttggggc aggagcagga ttccttcggt gggaactttg aaggaagcca gtccctggtg
1021 ggagacattg gaaatgtgaa catgtgggac tttgtgctgt caccagatga gattaacacc
1081 atctatcttg gcgggccctt cagtcctaat gtcctgaact ggcgggcact gaagtatgaa
1141 gtgcaaggcg aagtgttcac caaaccccag ctgtggccct gaggccagct gtgggtcctg
1201 aaggtacctc ccggtttttt acaccgcatg ggccccacgt ctctgtctct ggtacctccc
1261 gcttttttac actgcatggt tcccacgtct ctgtctctgg gcctttgttc ccctatatgc
1321 attgaggcct gctccaccct cctcagcgcc tgagaatgga ggtaaagtgt ctggtctggg
1381 agctcgttaa ctatgctggg aaatggtcca aaagaatcag aatttgaggt gttttgtttt
1441 catttttatt tcaagttgga cagatcttgg agataatttc ttacctcaca tagatgagaa
1501 aactaacacc cagaaaggag aaatgatgtt ataaaaaact cataaggcaa gagctgagaa
1561 ggaagcgctg atcttctatt taattcccca cccatgaccc ccagaaagca ggagcattgc
1621 ccacattcac agggctcttc agtctcagaa tcaggacact ggccaggtgt ctggtttggg
1681 tccagagtgc tcatcatcat gtcatagaac tgctgggccc aggtctcctg aaatgggaag
1741 cccagcaata ccacgcagtc cctccacttt ctcaaagcac actggaaagg ccattagaat
1801 tgccccagca gagcagatct gctttttttc cagagcaaaa tgaagcacta ggtataaata
1861 tgttgttact gccaagaact taaatgactg gtttttgttt gcttgcagtg ctttcttaat
1921 tttatggctc ttctgggaaa ctcctcccct tttccacacg aaccttgtgg ggctgtgaat
1981 tctttcttca tccccgcatt cccaatatac ccaggccaca agagtggacg tgaaccacag
2041 ggtgtcctgt cagaggagcc catctcccat ctccccagct ccctatctgg aggatagttg
2101 gatagttacg tgttcctagc aggaccaact acagtcttcc caaggattga gttatggact
2161 ttgggagtga gacatcttct tgctgctgga tttccaagct gagaggacgt gaacctggga
2221 ccaccagtag ccatcttgtt tgccacatgg agagagactg tgaggacaga agccaaactg
2281 gaagtggagg agccaaggga ttgacaaaca acagagcctt gaccacgtgg agtctctgaa
2341 tcagccttgt ctggaaccag atctacacct ggactgccca ggtctataag ccaataaagc
2401 ccctgtttac ttgagtgagt ccaagctgtt ttctgatagt tgctttagaa gttgtgacta
2461 acttctctat gacctttgaa
//