LOCUS HUMKTEP2A 1924 bp mRNA linear HUM 27-APR-1993
DEFINITION Human epidermal 67-kDa type II keratin mRNA.
ACCESSION M10938
VERSION M10938.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1924)
AUTHORS Steinert,P.M., Parry,D.A., Idler,W.W., Johnson,L.D., Steven,A.C.
and Roop,D.R.
TITLE Amino acid sequences of mouse and human epidermal type II keratins
of Mr 67,000 provide a systematic basis for the structural and
functional diversity of the end domains of keratin intermediate
filament subunits
JOURNAL J. Biol. Chem. 260 (11), 7142-7149 (1985)
PUBMED 2581964
COMMENT Original source text: Human foreskin cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1924
/db_xref="H-InvDB:HIT000194088"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS <1..1482
/note="type II keratin subunit protein"
/codon_start=1
/protein_id="AAA36153.1"
/translation="IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFI
DKVRFMEQQNKVLQTKWELLQQVDTSTRTHNLEPYFESFINNSRRRVDQLKSDQSRLD
SELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQE
IDFLTALYQAELSQMQTQISETNVILSMDNNRQFDLDSIIAEVKAQYEDIAQKSKAEA
ESLYQSKYEELQITAGRHGDSVRNSKIEISELNRMIQRLRSEIDNVKKQISNLQQSIS
DAEQRGENALKDAKNKLNDMEDALQQAKEDLARLLCDYHELMNTKLALDLEIATYRTL
LEGEESRMSGECAPNVSVTVSTSHTSMSGGGSRGGGGGGYGSGGSSYGSGGCSYGSGG
GGGGGRGSYGSGGSSYGSGGSSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG
RGSGGGSSGGSSGGRGSSSGGVKSSGGSSSVRFVSTSYSGVTR"
BASE COUNT 505 a 453 c 536 g 430 t
ORIGIN
1 atccaagaag tcactatcaa ccagagcctt cttcagcccc tcaatgtgga gattgaccct
61 gagatccaaa aggtgaagtc tcgagaaagg gagcaaatca agtcactcaa caaccaattt
121 gcctccttca ttgacaaggt gaggttcatg gagcagcaga acaaggtact gcaaacaaaa
181 tgggagctgc tgcagcaggt agatacctcc actagaaccc ataatttaga gccctacttt
241 gagtcattca tcaacaattc tcgaaggaga gtggaccaac tgaagagtga tcaatctcgg
301 ttggattcgg aactgaagaa catgcaggac atggtggagg attaccggaa caagtatgag
361 gatgaaatca acaagcggac aaatgcagag aatgaatttg tgaccatcaa gaaggatgtg
421 gatggtgctt atatgaccaa ggtggacctt caggccaaac ttgacaactt gcagcaggaa
481 attgatttcc ttacagcact ctaccaagca gagttgtctc agatgcagac tcaaatcagt
541 gaaactaatg tcatcctctc tatggacaac aaccgccagt tcgacctgga cagcatcatt
601 gctgaggtca aggcccagta cgaggatata gcccagaaga gcaaagctga ggccgagtcc
661 ttgtaccaga gcaagtatga agagctgcag atcactgctg gcagacatgg ggatagtgtg
721 agaaattcaa agatagaaat ttctgagctg aatcgaatga tacagagact tagatctgaa
781 atcgacaatg tcaagaagca gatctccaac ttgcagcagt ccatcagtga tgcagagcag
841 cgaggcgaga atgccctcaa ggatgccaag aacaagctga atgacatgga ggatgcactg
901 cagcaggcca aggaagacct agcccgcctg ctgtgcgact accatgagct gatgaacacc
961 aagctggccc tggatctgga gattgccacc tacaggaccc tccttgaggg tgaagaaagc
1021 aggatgtctg gagaatgtgc cccgaacgtg agtgtgactg tgagcacaag ccacaccagc
1081 atgagtggag gtggcagccg aggaggtggc ggcggtggct acggctctgg aggtagcagc
1141 tatggctccg gaggttgtag ctatggttct ggaggtggcg gcggcggcgg ccgtggcagc
1201 tatggctccg gaggtagcag ctacggctcc ggaggtagca gctatggctc tggtggtggc
1261 ggcggcggcc atggcagcta cggctccgga agcagcagtg ggggctacag aggtggctct
1321 ggaggcggcg gcggcggcag ttctggcggc cggggctctg gcggcgggag ctctggaggc
1381 tcctctggag gccggggatc cagctctggg ggtgtcaagt cctctggtgg cagttccagc
1441 gtgaggtttg tttctaccag ttattccgga gtaaccagat aaagagatgc cctctgtttc
1501 attagctcta gttctccccc agcatcacta acaaatatgc ttggcaagac cgaggtcgat
1561 ttgtcccagc cttaccggag aaaagagcta tggttagtta cactagctca tcctattccc
1621 ccagctcttt cttttctgct gtttcccaat gaagttttca gatcagtggc aatctcagtc
1681 ccttggctat gaccctgctt tgttgtttcc ctgagaaaca gttcagcagt gaccaccacc
1741 cacatgacat ttcaagcacc accttaagcc agccgaagta ggaccagtta gacccagggt
1801 gaggacagct ccttgcaatc ttaacactgt gctgttttgg ttttgtacat aaggtgtaag
1861 caagttgttt ttcttttgtg gagtggtctt aaactcccct tttccttgtt ttgctgctaa
1921 taaa
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