LOCUS HUMPTPC 5775 bp mRNA linear HUM 07-MAR-1997
DEFINITION Human protein tyrosine phosphatase mRNA, complete cds.
ACCESSION L77886
VERSION L77886.1
KEYWORDS protein tyrosine phosphatase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5775)
AUTHORS Yang,Y., Gil,M.C., Choi,E.Y., Park,S.H., Pyun,K.H. and Ha,H.
TITLE Molecular cloning and chromosomal localization of a human gene
homologous to the murine R-PTP-kappa, a receptor-type protein
tyrosine phosphatase
JOURNAL Gene 186 (1), 77-82 (1997)
PUBMED 9047348
FEATURES Location/Qualifiers
source 1..5775
/db_xref="H-InvDB:HIT000194048"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/cell_type="keratinocyte"
/tissue_type="foreskin"
/note="antisense = 'No'; hypothetical = 'No'"
gene 1..5775
/gene="R-PTP-kappa"
5'UTR 1..15
/gene="R-PTP-kappa"
CDS 16..4338
/gene="R-PTP-kappa"
/note="putative"
/codon_start=1
/product="protein tyrosine phosphatase"
/protein_id="AAC37599.1"
/translation="MDTTAAAAVPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGA
CDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKEND
THCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFW
PNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIA
TGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSER
GSGVSNFPQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTS
GSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRT
PKTLKIAEIQARRIAVDWESLGYNITRCHSFNVTICYHYFRGHNESKADCLDMDPKAP
QHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIF
LNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTT
YQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITVLLRPAQAKG
APISAYQIVVEELHPHRTKREAGAMECYQVPVTYQNAMSGGAPYYFACRTPPGNLPEP
APFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMTSVEKETKTQCVRIATKAAATEEPEV
IPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKSKLAKKRKDAMGNTRQEMTHM
VNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRYENHSATAESSRLLDVPRYLCEGTE
SPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAK
NRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWR
MIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTL
ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAG
RTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCG
ETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDK
NRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRL
VYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICN
LTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECKEGEGRTIIHCL
NGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEY
LESS"
sig_peptide 16..93
/gene="R-PTP-kappa"
/note="putative"
mat_peptide 94..4335
/gene="R-PTP-kappa"
/product="protein tyrosine phosphatase"
/note="putative"
3'UTR 4339..5775
/gene="R-PTP-kappa"
polyA_site 5775
/gene="R-PTP-kappa"
BASE COUNT 1707 a 1198 c 1264 g 1606 t
ORIGIN
1 acgagcaaac tcggcatgga tacgactgcg gcggcggccg tgcctgcttt tgtggcgctc
61 ttgctcctct ctccttggcc tctcctggga tcggcccaag gccagttctc cgcaggtggc
121 tgtacttttg atgatggtcc aggggcctgt gattaccacc aggatctgta tgatgacttt
181 gaatgggtgc atgttagtgc tcaagagcct cattatctac cacccgagat gccccaaggt
241 tcctatatga tagtggactc ttcagatcac gaccctggag aaaaagccag acttcagctg
301 cctacaatga aggagaacga cactcactgc attgatttca gttacctatt atatagccag
361 aaaggactga atcctggcac tttgaacata ttagttaggg tgaataaagg acctcttgcc
421 aatccaattt ggaatgtgac tggattcact ggtagagatt ggcttcgggc tgagctagca
481 gtgagcacct tttggcccaa tgaatatcag gtaatatttg aagctgaagt ctcagggggg
541 agaagtggtt atattgccat tgatgacatc caagtactga gttatccttg tgataaatct
601 cctcatttcc tccgtctagg ggatgtagag gtgaatgcag ggcaaaacgc tacatttcag
661 tgcattgcca cagggagaga tgctgtgcat aacaagttat ggctccagag acgaaatgga
721 gaagatatac cagtagccca gactaagaac atcaatcata gaaggtttgc cgcttccttc
781 agattgcaag aagtgacaaa aactgaccag gatttgtatc gctgtgtaac tcagtcagaa
841 cgaggttccg gtgtgtccaa ttttccccaa cttattgtga gagaaccgcc aagacccatt
901 gctcctcctc agcttcttgg tgttgggcct acatatttgc tgatccaact aaatgccaac
961 tcgatcattg gcgatggtcc tatcatcctg aaagaagtag agtaccgaat gacatcagga
1021 tcctggacag aaacccatgc agtcaatgct ccaacttaca aattatggca tttagatcca
1081 gataccgaat atgagatccg agttctactt acaagacctg gtgaaggtgg aacggggctc
1141 ccaggacctc cactaatcac cagaacaaaa tgtgcagaac ctatgagaac cccaaagaca
1201 ttaaagattg ctgaaataca ggcaagacgg attgctgtgg actgggaatc cttgggttac
1261 aacattacgc gttgccactc ttttaatgtc actatctgct accattactt ccgtggtcac
1321 aacgagagca aggcagactg tttggacatg gaccccaaag cccctcagca tgttgtgaac
1381 catctgccac cttatacaaa tgtcagcctc aagatgatcc taaccaatcc agagggaagg
1441 aaggagagtg aagagacaat tattcaaact gatgaagatg tgcctggtcc cgtaccagta
1501 aaatctcttc aaggaacatc ctttgaaaat aagatcttct tgaactggaa agaacctttg
1561 gatccaaatg gaatcatcac tcaatatgag atcagctata gcagtataag atcatttgat
1621 cctgcagttc cagtggctgg acctccccag actgtatcaa atttatggaa cagtacacac
1681 catgtcttta tgcatctcca ccctggaacc acgtaccagt ttttcataag agccagcacg
1741 gtcaaaggct ttggtccagc cacagccatc aatgtcacca ccaatatctc agctccaact
1801 ttacctgact atgaaggagt tgatgcctct ctcaatgaaa ctgccaccac aataactgta
1861 ttgttgagac cagcacaagc caaaggtgct cctatcagtg cttatcagat tgttgtggaa
1921 gaactgcacc cacaccgaac caagagagaa gccggagcca tggaatgcta ccaggttcct
1981 gtcacatacc aaaatgccat gagtgggggt gcaccgtatt actttgcctg cagaactccc
2041 cccggaaacc tacctgagcc tgccccgttc actgtgggtg acaatcggac ctaccaaggc
2101 ttttggaacc ctcctttggc tccgcgcaaa ggatacaaca tctatttcca ggcgatgacg
2161 agtgtggaga aggaaactaa aacccagtgc gtacgcattg ctacaaaagc agcagcaaca
2221 gaagaaccag aagtgatccc agatcccgcc aagcagacag acagagtggt gaaaatagca
2281 ggaattagtg ctggaatttt ggtgttcatc ctccttctcc tagttgtcat attaattgta
2341 aaaaagagca aacttgctaa aaaacgcaaa gatgccatgg ggaatacccg gcaggagatg
2401 actcacatgg tgaatgcaat ggatcgaagt tatgctgatc agagcactct gcatgcagaa
2461 gatcctcttt ccatcacctt catggaccaa cataacttta gtccaagata tgagaaccac
2521 agtgctacag cagagtccag tcgccttcta gacgtacctc gctacctctg tgaggggacg
2581 gaatcccctt accagacagg acagctgcat ccagccatca gggtagctga tttactgcag
2641 cacattaatc tcatgaagac atcagacagc tatgggttca aagaggaata tgagagcttt
2701 tttgaaggac agtcagcatc ttgggatgta gctaaaaaag atcaaaatag agcaaaaaac
2761 cgatatggaa acattatagc atatgatcac tccagagtga ttttgcaacc cgtagaggat
2821 gatccttcct cagattatat taatgccaac tatattgatg gctaccagag accaagtcat
2881 tacattgcaa cccaaggtcc cgttcatgaa acagtgtatg atttctggag gatgatttgg
2941 caagaacaat ctgcttgcat tgtgatggtt acaaatttag ttgaggttgg ccgggttaaa
3001 tgctataaat attggcctga tgatactgaa gtttatggtg acttcaaagt aacgtgtgta
3061 gaaatggaac cacttgctga atatgtagtt aggacattca ccctggaaag gagggggtac
3121 aatgaaatcc gtgaagttaa acagttccat ttcacgggct ggcctgacca tggagtgccc
3181 taccatgcta cagggctgct ttcctttatc cggcgagtca agttatcaaa ccctcccagt
3241 gctggcccca tcgttgtaca ttgcagtgct ggtgctggac gaactggctg ctacattgtg
3301 attgacatca tgctagacat ggctgaaaga gagggtgttg ttgatattta caattgtgtc
3361 aaagccttaa gatctcggcg tattaatatg gtccagacag aggaacagta catttttatt
3421 catgatgcca ttttagaagc ctgcttatgt ggagaaactg ccatacctgt ctgtgaattt
3481 aaagctgcat attttgatat gattagaata gactcccaga ctaactcttc acatctcaag
3541 gatgaatttc agactctgaa ttcagtcacc cctcgactac aagctgaaga ctgcagtata
3601 gcgtgcctgc caaggaacca tgacaagaac cgtttcatgg acatgctgcc acctgacaga
3661 tgtctgcctt ttttaattac aattgatggg gagagcagta actacatcaa tgctgctctt
3721 atggacagct acaggcaacc agctgctttc atcgtcacac aataccctct gccaaacact
3781 gtaaaagact tctggagatt agtgtatgat tatggctgta cctccattgt gatgttaaac
3841 gaagtcgact tgtcccaggg ctgccctcag tactggccag aggaagggat gctacgatat
3901 ggccccatcc aagtggaatg tatgtcttgt tcaatggact gtgatgtgat caaccggatt
3961 tttaggatat gcaatctaac aagaccacag gaaggttatc tgatggtgca acagtttcag
4021 tacctaggat gggcttctca tcgagaagtg cctggatcca aaaggtcatt cttgaaactg
4081 atacttcagg tggaaaagtg gcaggaggaa tgcaaggagg gggaaggccg gacgattatc
4141 cactgcctaa atggtggcgg gcgaagtggc atgttctgtg ctataggcat cgttgttgaa
4201 atggtgaaac ggcaaaatgt tgtcgatgtt ttccatgcag taaagacact gaggaacagc
4261 aagccaaaca tggtggaagc cccggagcaa taccgtttct gctatgatgt agctttggag
4321 tacctggaat catcttagtt gggtgagact ctttaaagtg catccatgaa gaaacctgtc
4381 catctattga gccagcagct gttgtacctg ttacacttgt gcagaaagat tttaatgtgg
4441 ggggtgggag acttttacat ttgagaggta aaagtatttt ttttatgaag ttgtgtatct
4501 taataaaaag gactgaatta gtttttatta ctatattaaa gcatcaacat ttcatgccac
4561 ataaattata tttaataaga accagattga aatgagaacg tattggtgtt tgtacagtga
4621 acatgccacc ttttttctca tggtttcagt agagcagcta ccacatgttg catgagttca
4681 tactttctac gtggcatttt tctccctttc taaaatgaaa gctgatgaat cttaaaagga
4741 agaagaaaag aaaagctgtg caaattcata gtaaagttcg ttttttatat gtttccagtg
4801 tagcagatct ctatataaat atataaatat atataactgg cttattttct tttaatgtgc
4861 aatgatggct ggatcattta aagttctttt tagaaaataa cataagccaa agactcaagt
4921 gtaaatatgt ctatatggag aaagcacatt atatttattg gttacttaca ttcctttttt
4981 gatggctaaa atactaccac cacacaatca tctttttttc ctgaagaaag ctttttcttt
5041 agctaaaatc aattgtaaac gatttttgta gattattttt tgtatgtttt agtgtaagta
5101 gaagataaac tttttattca taaaccagga agcaatgttc tttatagtga ttctcttgtg
5161 tacatgcttg tgaattaaat ttgtgtaaaa tcccttggca attgggtctt ttaatatagg
5221 accaaattaa aacattttgc tgaatatgta tagtttttca caatttcatt aggtaaataa
5281 tggtttggtg atacattgag aaatgtacac attaaaaggc cttgctgaca acttgcacaa
5341 tgttgaacat agcctttaag catcatttaa attttaaagg aatggagttt ttcagcctgt
5401 ggcccagcac tggtcaagaa aacaagatgg caacatatat gctttcaggg tcaaatttga
5461 gcaaactgta aactgtcagg gtgataaaat gtttctcttg atgtttacat gcacaagctt
5521 tgcgttctga ctataaaaag tgtgaacaaa tcaatgccag attcctgttt tgcgcattgt
5581 catgggattc ttaagtgaac ctttctaaat gtggtcttgt tcacatgctc cacgtagctg
5641 taacttcaca tcatcagctt gcagtttgta attgactaaa gcattccagt gtcctctttc
5701 tagattgcca gctcatgaca tggtgcttat aaagatttaa ttaaagtaag aatgaaataa
5761 agtttttata attat
//