LOCUS HUMFE65 2654 bp mRNA linear HUM 31-DEC-1997
DEFINITION Homo sapiens stat-like protein (Fe65) mRNA, complete cds.
ACCESSION L77864
VERSION L77864.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2654)
AUTHORS Bressler,S.L., Gray,M.D., Sopher,B.L., Hu,Q., Hearn,M.G.,
Pham,D.G., Dinulos,M.B., Fukuchi,K., Sisodia,S.S., Miller,M.A.,
Disteche,C.M. and Martin,G.M.
TITLE cDNA cloning and chromosome mapping of the human Fe65 gene:
interaction of the conserved cytoplasmic domains of the human
beta-amyloid precursor protein and its homologues with the mouse
Fe65 protein
JOURNAL Hum. Mol. Genet. 5 (10), 1589-1598 (1996)
PUBMED 8894693
REFERENCE 2 (bases 1 to 2654)
AUTHORS Hu,Q., Kukull,W.A., Bressler,S.L., Gray,M.D., Cam,J.A., Larson,E.,
Martin,G.M. and Deeb,S.S.
TITLE The human FE65 gene: genomic structure and intronic polymorphisms
associated with sporadic dementia of the alzheimer type
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2654)
AUTHORS Hu,Q.
TITLE Direct Submission
JOURNAL Submitted (31-DEC-1997) Pathology, University of Washington, 1959
N.E. Pacific Ave., Seattle, WA 98195, USA
REMARK Sequence update by submitter
COMMENT On Dec 31, 1997 this sequence version replaced gi:1929896.
GSDB:S:75831.
FEATURES Location/Qualifiers
source 1..2654
/db_xref="H-InvDB:HIT000194047"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/clone_lib="Stratagene #936206"
/dev_stage="fetal"
gene <1..2654
/gene="Fe65"
5'UTR <1..100
/gene="Fe65"
CDS 101..2233
/gene="Fe65"
/codon_start=1
/product="stat-like protein"
/protein_id="AAB93631.1"
/translation="MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATA
VGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQE
PEMAPLGPKGLIHLYSELELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEE
EEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAAS
DEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTG
TTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEP
EEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSV
AVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPQSQALLHAQPIISI
RVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRN
ARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGAL
ESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFI
MAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVA
RRVGWTVRRGVQSLWGSLKPKRLGAHTP"
3'UTR 2234..2643
/gene="Fe65"
polyA_site 2643
/gene="Fe65"
BASE COUNT 580 a 801 c 797 g 476 t
ORIGIN
1 atgttgtgat ggagaagccg cggcggagcc cgaaccccgc agcctgagcc acctccgtca
61 tctgggcccg gggcctcacc gcgcaggagc tgccaaggcc atgtctgttc catcatcact
121 gagccagtcg gccattaatg ccaacagcca cggaggcccc gcactgagcc tacccctgcc
181 tctgcacgct gcccacaacc agctgctcaa cgccaagctg caggccacag ctgtgggacc
241 caaggacctg cgcagcgcca tgggggaggg tggtgggcct gagccaggcc ctgccaatgc
301 caagtggcta aaagagggcc agaaccagct ccggcgggcc gccacggccc accgtgacca
361 gaatcgcaat gtgaccttga ccttggcgga ggaggccagc caggagcctg agatggcacc
421 cttgggcccc aaaggcctga tacacctgta ctctgagctg gagctctcag ctcacaacgc
481 agccaaccga ggcctacgag gacctggcct gatcatcagc actcaagagc aggggccaga
541 tgagggagag gagaaggcgg ccggggaggc cgaggaggag gaggaggatg atgatgatga
601 agaggaggag gaggacttat cttctccccc agggctgcct gagcccctgg agagtgtgga
661 ggcccccccc aggccccaag cccttacaga tggcccccgg gaacacagca agagtgccag
721 cctcctgttt ggcatgcgga acagtgcagc cagtgatgag gactcaagct gggctacctt
781 atctcagggc agcccctcct atggctcccc agaggacaca gattccttct ggaaccccaa
841 cgccttcgag acggattccg acctgccggc tggatggatg agggtccagg acacctcagg
901 gacctattac tggcacatcc caacagggac cacccagtgg gaaccccccg gccgggcctc
961 cccctcacag gggagcagcc cccaagagga gtcccagctc acctggacag gttttgctca
1021 tggagaaggc tttgaggatg gagaattttg gaaggatgaa cccagtgatg aggccccaat
1081 ggagctggga ctgaaggaac ctgaggaggg gacgttgacc ttcccagctc agagcctcag
1141 cccagagccg ttgccccaag aggaggagaa gcttccccca cggaatacca acccagggat
1201 caagtgtttc gccgtgcgct ccctaggctg ggtagagatg accgaggagg agctggcccc
1261 tggacgcagc agtgtggcag tcaacaattg catccgtcag ctctcttacc acaaaaacaa
1321 cctgcatgac cccatgtctg ggggctgggg ggaaggaaag gatctgctac tgcagctgga
1381 ggatgagaca ctaaagctag tggagccaca gagccaggca ctgctgcacg cccaacccat
1441 catcagcatc cgcgtgtggg gcgtcgggcg ggacagtgga agagagaggg actttgccta
1501 cgtagctcgt gataagctga cccagatgct caagtgccac gtgtttcgct gtgaggcacc
1561 tgccaagaac atcgccacca gcctgcatga gatctgctct aagatcatgg ccgaacggcg
1621 taatgcccgc tgcttggtaa atggactctc cctggaccac tctaaacttg tggatgtccc
1681 tttccaagtg gaattcccag cgcctaagaa tgagttggtc cagaagttcc aagtctatta
1741 cctggggaat gtacctgttg ctaaacctgt tggggtagat gtgattaatg gggccctcga
1801 gtcagtcctg tcctccagca gccgtgaaca atggacccca agtcatgtca gtgtggcccc
1861 tgctaccctc accatcttgc accagcagac agaggcagtg ctgggagagt gtcgggtgcg
1921 tttcctctcc ttcctggccg tgggcagaga tgtccacacg tttgcattca tcatggctgc
1981 cggcccagcc tccttctgct gccacatgtt ctggtgcgag cccaatgctg ccagcctctc
2041 agaggctgtg caggctgcgt gcatgcttcg ctaccagaag tgtctggatg cccgttccca
2101 ggcctccacc tcctgcctcc cagcaccccc tgctgagtct gtggcacggc gtgtagggtg
2161 gactgtccgc aggggtgttc agtcgctgtg gggctccctg aagcccaaac ggctgggggc
2221 ccatacccca tgaagaagcc cccaccttcc cttccacctg attgtgttgg gccccaggga
2281 actaaagggt gtgggtcagg gaggggtcta gaggctattc ctaggcctca ggcctcccaa
2341 atatgcccct ccccagtagg tacggttccc tgcctaggag ctggggaggg agagatctaa
2401 tcccttcaag gaagtgataa cactggagtg gtaacaagag gagcaggaag caaggccagc
2461 cctggttctc catccccatg tgtttcaggt ggaacaggag gaactggtcc aggccaggcc
2521 tcatcctcct ggacccagca ggggcagaag gaggaaggga ctggtccagg catgggtccc
2581 ttccccctgc tccatgggca cctctgctgt attgatatca ctaataaagt ctgtctgcac
2641 tgcaaaaaaa aaaa
//