LOCUS HUMB56EA 3270 bp mRNA linear HUM 09-SEP-1997
DEFINITION Homo sapiens protein phosphatase 2A B56-epsilon (PP2A) mRNA,
complete cds.
ACCESSION L76703
VERSION L76703.1
KEYWORDS protein phosphatase 2A; PP2A; regulatory subunit B56/B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3270)
AUTHORS McCright,B., Brothman,A.R. and Virshup,D.M.
TITLE Assignment of human protein phosphatase 2A regulatory subunit genes
b56alpha, b56beta, b56gamma, b56delta, and b56epsilon
(PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to
chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12
JOURNAL Genomics 36 (1), 168-170 (1996)
PUBMED 8812429
REFERENCE 2 (bases 1 to 3270)
AUTHORS McCright,B., Rivers,A.M., Audlin,S. and Virshup,D.M.
TITLE The B56 family of protein phosphatase 2A (PP2A) regulatory subunits
encodes differentiation-induced phosphoproteins that target PP2A to
both nucleus and cytoplasm
JOURNAL J. Biol. Chem. 271 (36), 22081-22089 (1996)
PUBMED 8703017
REFERENCE 3 (bases 1 to 3270)
AUTHORS Virshup,D.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-1997) HMBG, University of Utah, Bldg. 533, RM
4480, Salt Lake City, UT 84112, USA
COMMENT Original source text: Homo sapiens fetal brain cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3270
/db_xref="H-InvDB:HIT000194000"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..3270
/gene="PP2A"
mRNA 1..3270
/gene="PP2A"
/experiment="experimental evidence, no additional details
recorded"
5'UTR 1..567
/gene="PP2A"
CDS 568..1971
/gene="PP2A"
/experiment="experimental evidence, no additional details
recorded"
/note="similar to yeast RTS1"
/codon_start=1
/product="protein phosphatase B56-epsilon"
/protein_id="AAB69752.1"
/translation="MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIE
LTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITI
SRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIR
FLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIR
KQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRS
LSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEP
SQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLY
RISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKL
EDLELKRGLRRDGIIPT"
3'UTR 1972..3270
/gene="PP2A"
BASE COUNT 971 a 708 c 701 g 890 t
ORIGIN
1 cgccgcccgg tgatattgac aataggagag agaaaggggc attgactggg acccaccgcg
61 ggtagcgaaa ggtggctctg gcagcggcgg ctccagctcc tgcggctcct cctccttatt
121 ctgtcccctt ctcttgctgc cgctgcagat ccagtcttcc tccctccctt ccccccctcc
181 ccacgtcgtc gccgccgccg ccgggtccgg ggcaacgagc tgaggcgccg cccgccagga
241 atgtgagcga ggagccaccg gcggagccgc aacggggtcg gtgccgattt gatgggacgg
301 gcccgcgggg gaggatcgtg aggccgccgc cgccaccgga acgctgaggt tcgggtccgg
361 ccgtgaggcc tagaggctcc gccgccgcgg aaccggaggg accccgtacc ggacagccgt
421 cgccccaggc tccccgcagc tgcccggacc tccccctgca cgtcccggtc ccgccgcccg
481 cccccgctgc ggccacctcg cccgtctccc gcccctccaa gccacagatc atcttcggat
541 tcttccccag aagcttcaag tagggatatg tcctcagcac caactactcc tccatcagtg
601 gataaagtag acggattttc tcggaagtcc gtcagaaaag ccagacagaa gaggtcgcaa
661 agttcctcac agtttaggtc tcaaggcaag cctattgagt taacacctct gccgctgcta
721 aaagacgttc catcctcaga gcagcctgaa ctgttcctaa agaaacttca gcagtgctgt
781 gtcatttttg acttcatgga cacgctatct gatcttaaaa tgaaagaata caagcgctcc
841 actcttaatg aactggtgga ctacattaca ataagcagag gctgtttgac agagcagact
901 taccctgaag tagttagaat ggtatcttgc aatatattca gaactctccc tcctagtgac
961 agcaatgaat ttgatccaga agaagatgaa cctacccttg aggcatcgtg gccacactta
1021 cagcttgtat atgaattttt catacgattt ttggaaagcc aagaattcca acccagcatt
1081 gccaaaaaat atatagatca gaaatttgta ttacagcttc tggagctatt tgacagcgaa
1141 gaccctcggg aacgggacta cttaaaaaca gtcttacaca gaatttatgg caagtttctt
1201 ggtcttagag catttatccg aaaacagatt aacaatattt ttctaaggtt tgtttatgaa
1261 acagaacact tcaatggtgt agctgaactg ctggaaatat taggaagtat tatcaatggc
1321 tttgctttac ctcttaaggc agaacacaaa cagtttctgg tgaaagtatt gatcccttta
1381 cacactgtca ggagcttatc actcttccat gcacagctgg catattgtat agtacagttt
1441 ctggagaaag atccttcact cacagaacca gttattaggg ggttaatgaa attttggcct
1501 aaaacatgta gtcaaaaaga ggtcatgttc cttggggaac tggaagaaat attggatgtg
1561 attgaacctt cacaatttgt taaaatccaa gaacctttgt ttaaacaaat cgccaagtgt
1621 gtatctagcc cccattttca ggtggcagaa agagcactct attattggaa taatgaatac
1681 atcatgagtt tgatagaaga aaactctaac gtcatccttc ccatcatgtt ttccagcctt
1741 tataggattt caaaagaaca ttggaatccg gctattgtgg cgttggtgta caatgtgttg
1801 aaggcattta tggaaatgaa cagcaccatg tttgacgagc tgacagccac atacaagtca
1861 gatcgtcagc gtgagaaaaa gaaagaaaag gagcgtgaag aattgtggaa aaaattggag
1921 gatctggagt taaagagagg tcttagacgt gatggaataa ttccaactta acaaaaacaa
1981 tgacaacaac attactaacc tgtggagtca cacgtttatg tagtagaaga tggagcaaca
2041 gttttctgta ttgtgcaact ttacagtaga tttcaccttt gtttcattat tacagcagca
2101 ctgtatatac ctgtctctaa gtaaaggaaa aaacaaaata aggacttcaa tccaaagttt
2161 ggacagtaga tggacttctc agaactttgc aaacataatc attgttctca ccctctttta
2221 aaaaaaaaaa atcggtcttc aaagatctgt tgatgaaatt gctatgttaa aattccatta
2281 tcgggagttc cttatttatc actagcagag agtatgatac aattttcaaa tgtgaacaat
2341 cttaaattta gcttgtcttt ctgctaagct gttaaatgta tttatagtaa aggaagaaaa
2401 aaagactgtc atttccttat aagtttgtgt aacatcctcc tctggataac ttgactgtaa
2461 tttaacatct ttttcttttg cacatcttcc tgagttgaat gtccacgtgg aatggggtca
2521 tgaattataa aagtccctga taaaagtttt gtttactggg gtgaacatct ttccagtaac
2581 caggtagtcc tggtactcct ttagttttaa aattaggagt taagagagaa gaggtgataa
2641 acatagtagg gaagggaata tcggattcat gcatcagttt atggtgaatc caaatcaatg
2701 tcttgaatcc tttgaaaaca ggcactggga catcacaggc ttcagtacct gaccagtatt
2761 agttgcatat atcattgaac acacatacca gagatgtttt agaaatgtga gaaaaacatc
2821 cttttggacc atttgaaata agaaagacaa acactaaaca atacaaccat gaaattgatc
2881 accgggattg caaatctaat tgggaaaaga gttgagcaaa cagcttggac tgtttggagt
2941 tgttgcctta ctttttaata tgtatttata aagtattcca gcaaaagagg atgtagcctc
3001 tgggaaaaaa caaacatgtt acagtgtttt ttgtagattc tcgttctata tctcatcaca
3061 gcgccagccc tgtttttagc cggaaaggat tcaggataaa cattattatg cattctgaat
3121 tggatgcata ttcctaacta ctgtatttgt taccaaaagt ggttctacaa atgctactga
3181 aaaaaatctg gaaattccta atgtcctgag tattaataat aaagtttaaa aatgctttta
3241 tatcaaaggt gcatcgtgac caaattgttt
//