LOCUS HUMB56DA 3048 bp mRNA linear HUM 09-SEP-1997
DEFINITION Homo sapiens protein phosphatase 2A B56-delta (PP2A) mRNA, complete
cds.
ACCESSION L76702
VERSION L76702.1
KEYWORDS protein phosphatase 2A; PP2A; regulatory subunit B56/B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3048)
AUTHORS Tanabe,O., Nagase,T., Murakami,T., Nozaki,H., Usui,H., Nishito,Y.,
Hayashi,H., Kagamiyama,H. and Takeda,M.
TITLE Molecular cloning of a 74-kDa regulatory subunit (B' or delta) of
human protein phosphatase 2A
JOURNAL FEBS Lett. 379 (1), 107-111 (1996)
PUBMED 8566219
REFERENCE 2 (bases 1 to 3048)
AUTHORS McCright,B., Brothman,A.R. and Virshup,D.M.
TITLE Assignment of human protein phosphatase 2A regulatory subunit genes
b56alpha, b56beta, b56gamma, b56delta, and b56epsilon
(PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to
chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12
JOURNAL Genomics 36 (1), 168-170 (1996)
PUBMED 8812429
REFERENCE 3 (bases 1 to 3048)
AUTHORS McCright,B., Rivers,A.M., Audlin,S. and Virshup,D.M.
TITLE The B56 family of protein phosphatase 2A (PP2A) regulatory subunits
encodes differentiation-induced phosphoproteins that target PP2A to
both nucleus and cytoplasm
JOURNAL J. Biol. Chem. 271 (36), 22081-22089 (1996)
PUBMED 8703017
REFERENCE 4 (bases 1 to 3048)
AUTHORS Virshup,D.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-1997) HMBG, University of Utah, Bldg. 533, RM
4480, Salt Lake City, UT 84112, USA
COMMENT Original source text: Homo sapiens fetal brain cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3048
/db_xref="H-InvDB:HIT000193999"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..3048
/gene="PP2A"
mRNA 1..3048
/gene="PP2A"
/experiment="experimental evidence, no additional details
recorded"
5'UTR 1..187
/gene="PP2A"
CDS 188..1996
/gene="PP2A"
/experiment="experimental evidence, no additional details
recorded"
/note="similar to yeast RTS1"
/codon_start=1
/product="protein phosphatase 2A B56-delta"
/protein_id="AAB69751.1"
/translation="MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEAQPQPQPQP
QPQAQSQPPSSNKRPSNSTPPPTQLSKIKYSGGPQIVKKERRQSSSRFNLSKNRELQK
LPALKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSR
DVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFL
RFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYI
RRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVK
SLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIE
PSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPAL
YRNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQK
IEELARLNPQYPMFRAPPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEK
VLLRRKSELPQDVYTIKALEAHKRAEEFLTASQEAL"
3'UTR 1997..3048
/gene="PP2A"
BASE COUNT 750 a 855 c 808 g 635 t
ORIGIN
1 ccttcaatgt gaagctaata tctcctatag catagttaat gtttattcaa caaatattca
61 tgcagcggag tcaagaacac accacgatgg cggagaaagg aagagacgcc gagcggccga
121 gtgcggccga gcaaagccgg agccggagcg gggccgcagg agacgggccg ggtccggacg
181 ggccgagatg ccctataaac tgaaaaagga gaaggagccc cccaaggttg ccaaatgcac
241 agccaagcct agcagctcgg gcaaggatgg tggaggcgag aacactgagg aggcccagcc
301 gcagccccag ccccagcccc agccccaagc ccagtctcag ccaccgtcat ccaacaagcg
361 tcccagcaat agcacgccgc cccccacgca gctcagcaaa atcaagtact caggggggcc
421 ccagattgtc aagaaggagc gacggcaaag ctcctcccgc ttcaacctca gcaagaatcg
481 ggagctgcag aagcttcctg ccctgaaaga ttcgccaacc caggagcggg aggagctgtt
541 tatccagaag ctacgccagt gctgtgtcct ctttgacttc gtgtcagacc cactcagtga
601 cctcaaattc aaggaggtga agcgggcagg actcaacgag atggtggagt acatcaccca
661 tagccgtgat gttgtcactg aggccattta ccctgaggct gtcaccatgt tttcagtgaa
721 cctcttccgg acgctgccac cttcatcgaa tcccacaggg gctgagtttg acccagagga
781 agatgagccc accctggaag ctgcttggcc acatctccag ctcgtgtatg agttcttctt
841 acgtttcctt gagtctcctg atttccagcc aaacatagcc aagaagtaca tcgaccagaa
901 gtttgtactt gctctcctag acctatttga cagtgaggat cctcgagagc gggacttcct
961 caagaccatt ttgcatcgca tctatggcaa gtttttgggg ctccgggctt atatccgtag
1021 gcagatcaac cacatcttct acaggttcat ctacgagacg gagcatcaca acgggattgc
1081 tgagctcctg gagatcctgg gcagcatcat caatggcttt gctctgcccc ttaaagaaga
1141 gcacaagatg ttcctcatcc gtgtcctact tccccttcac aaggtcaagt ccctgagtgt
1201 ctaccaccct cagctggcat actgtgtggt acaattcctg gagaaggaga gcagtctgac
1261 tgagccggta attgtgggac ttctcaagtt ttggcccaag acccacagcc ccaaggaggt
1321 gatgttcttg aatgagctgg aggagattct ggacgtcatt gaaccttctg agttcagcaa
1381 agtgatggaa cccctcttcc gccagctggc caagtgtgtc tctagccccc atttccaggt
1441 ggcagagcgt gctctctatt actggaacaa tgagtacatc atgagcctga taagtgacaa
1501 tgctgcccga gtcctcccca tcatgttccc tgcactctac aggaactcca agagccactg
1561 gaacaagaca atccatggac tgatctataa tgccctgaag ttgtttatgg aaatgaatca
1621 gaagctgttt gatgactgca cacaacaata caaggcagag aagcagaagg gccggttccg
1681 aatgaaggaa agggaagaga tgtggcaaaa aatcgaggag ctggcccggc ttaatcccca
1741 gtatcccatg ttccgagccc ctccaccact gccccctgtg tactcgatgg agacagagac
1801 ccccacagct gaggacatcc agcttctgaa gaggactgtg gagactgagg ctgttcagat
1861 gctaaaagac atcaagaagg agaaagtgct gctgcggagg aagtcggagc tgccccagga
1921 cgtgtacacc atcaaggcac tggaggcgca caagcgggcg gaagagttcc taactgccag
1981 ccaggaggct ctctgacccc tcacgttcct accacagggc cacagcccac acagccctgg
2041 gacactgccc tggccctcca tactctgctc cctactggct gtcttggggg aaggcagcgc
2101 ctctctagct actcaaggga gggggatgtg ggcacttgaa gcagggacac ccacagaatg
2161 gtccctcttc tccccaaaag gtgttcatgc ctccctgtgg ctagtacagg ctgagcacta
2221 agatgcttag tgctcagaca acctggggat gcctgtcccc tacctgctcc tcacccacag
2281 ctacctgagg ctgctctgag aagtacacac aggaatacat acgctcctct attcttccct
2341 tcatcctcat ttgaacgcca ggtatctccc ctcctctctc tcccctgcag aggcatgtag
2401 ggaacagcag gagattattc tcaccaaagt tatgtcaagc cccattggtc ccagagtagc
2461 tgaagggaag ccaacccccc tgcagcacaa ataggccccc cagtcccagc cgtgtgctgg
2521 cagatagggt tgtattattt cttcttaccc catgcctgac caagggaggt caaaaggaga
2581 aaagtatagg ctgtggacaa taactgatga atatagggcc cagatggacc aagtggggcc
2641 ggggagggat gaataaacac cctaccccgt gccctgtctt tggtgagcag cagccctggg
2701 gtcacagaca tggaagggac caccctgggg ctgactgctt ttctgtgctg ttggttccca
2761 aaactagaaa gaaggaagca gggagcggtg ccccaagcat ggctcctgcc aacacctatt
2821 tatttccttg tttgtgctat gctgggcagg ccttctcttg tcccttatag gtaccttgga
2881 ggggccaggg gctgaggaag gccggaccca ggttccaggg gcgcaggcag tgcggctttt
2941 ggctgtgtac atagggtgct ttattctcca cagagtgata catgctaagg tgggttgggc
3001 ttggaccgat gtccccatat gtacagaact gaataaagtg ggtctctg
//