LOCUS HUMI1R 3590 bp mRNA linear HUM 11-MAR-1996
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase (IRAK) mRNA,
complete cds.
ACCESSION L76191
VERSION L76191.1
KEYWORDS interleukin 1 receptor; protein kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3590)
AUTHORS Cao,Z., Henzel,W.J. and Gao,X.
TITLE IRAK: a kinase associated with the interleukin-1 receptor
JOURNAL Science 271 (5252), 1128-1131 (1996)
PUBMED 8599092
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3590
/db_xref="H-InvDB:HIT000193971"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..3590
5'UTR 1..79
CDS 80..2218
/codon_start=1
/product="interleukin-1 receptor-associated kinase"
/protein_id="AAC41949.1"
/translation="MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQ
FAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAW
HPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGL
VPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPSPFCWPLCEISRGTHNFSEELKI
GEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAG
YCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLP
EEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALR
STQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRR
PPMTQVYERLEKLQAVVAGVPGHLEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAA
PSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGD
TAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALD
SLQLLSSSSLPGLGLEQDRQGPEESDEFQS"
3'UTR 2219..3590
BASE COUNT 712 a 1112 c 1129 g 637 t
ORIGIN
1 cgcggacccg gccggcccag gcccgcgccc gccgcggccc tgagaggccc cggcaggtcc
61 cggcccggcg gcggcagcca tggccggggg gccgggcccg ggggagcccg cagcccccgg
121 cgcccagcac ttcttgtacg aggtgccgcc ctgggtcatg tgccgcttct acaaagtgat
181 ggacgccctg gagcccgccg actggtgcca gttcgccgcc ctgatcgtgc gcgaccagac
241 cgagctgcgg ctgtgcgagc gctccgggca gcgcacggcc agcgtcctgt ggccctggat
301 caaccgcaac gcccgtgtgg ccgacctcgt gcacatcctc acgcacctgc agctgctccg
361 tgcgcgggac atcatcacag cctggcaccc tcccgccccg cttccgtccc caggcaccac
421 tgccccgagg cccagcagca tccctgcacc cgccgaggcc gaggcctgga gcccccggaa
481 gttgccatcc tcagcctcca ccttcctctc cccagctttt ccaggctccc agacccattc
541 agggcctgag ctcggcctgg ttccaagccc tgcttccctg tggcctccac cgccatctcc
601 agccccttct tctaccaagc caggcccaga gagctcagtg tccctcctgc agggagcccg
661 cccctctccg ttttgctggc ccctctgtga gatttcccgg ggcacccaca acttctcgga
721 ggagctcaag atcggggagg gtggctttgg gtgcgtgtac cgggcggtga tgaggaacac
781 ggtgtatgct gtgaagaggc tgaaggagaa cgctgacctg gagtggactg cagtgaagca
841 gagcttcctg accgaggtgg agcagctgtc caggtttcgt cacccaaaca ttgtggactt
901 tgctggctac tgtgctcaga acggcttcta ctgcctggtg tacggcttcc tgcccaacgg
961 ctccctggag gaccgtctcc actgccagac ccaggcctgc ccacctctct cctggcctca
1021 gcgactggac atccttctgg gtacagcccg ggcaattcag tttctacatc aggacagccc
1081 cagcctcatc catggagaca tcaagagttc caacgtcctt ctggatgaga ggctgacacc
1141 caagctggga gactttggcc tggcccggtt cagccgcttt gccgggtcca gccccagcca
1201 gagcagcatg gtggcccgga cacagacagt gcggggcacc ctggcctacc tgcccgagga
1261 gtacatcaag acgggaaggc tggctgtgga cacggacacc ttcagctttg gggtggtagt
1321 gctagagacc ttggctggtc agagggctgt gaagacgcac ggtgccagga ccaagtatct
1381 gaaagacctg gtggaagagg aggctgagga ggctggagtg gctttgagaa gcacccagag
1441 cacactgcaa gcaggtctgg ctgcagatgc ctgggctgct cccatcgcca tgcagatcta
1501 caagaagcac ctggacccca ggcccgggcc ctgcccacct gagctgggcc tgggcctggg
1561 ccagctggcc tgctgctgcc tgcaccgccg ggccaaaagg aggcctccta tgacccaggt
1621 gtacgagagg ctagagaagc tgcaggcagt ggtggcgggg gtgcccgggc atttggaggc
1681 cgccagctgc atcccccctt ccccgcagga gaactcctac gtgtccagca ctggcagagc
1741 ccacagtggg gctgctccat ggcagcccct ggcagcgcca tcaggagcca gtgcccaggc
1801 agcagagcag ctgcagagag gccccaacca gcccgtggag agtgacgaga gcctaggcgg
1861 cctctctgct gccctgcgct cctggcactt gactccaagc tgccctctgg acccagcacc
1921 cctcagggag gccggctgtc ctcaggggga cacggcagga gaatcgagct gggggagtgg
1981 cccaggatcc cggcccacag ccgtggaagg actggccctt ggcagctctg catcatcgtc
2041 gtcagagcca ccgcagatta tcatcaaccc tgcccgacag aagatggtcc agaagctggc
2101 cctgtacgag gatggggccc tggacagcct gcagctgctg tcgtccagct ccctcccagg
2161 cttgggcctg gaacaggaca ggcaggggcc cgaagaaagt gatgaatttc agagctgatg
2221 tgttcacctg ggcagatccc ccaaatccgg aagtcaaagt tctcatggtc agaagttctc
2281 atggtgcacg agtcctcagc actctgccgg cagtgggggt gggggcccat gcccgcgggg
2341 gagagaagga ggtggccctg ctgttctagg ctctgtgggc ataggcaggc agagtggaac
2401 cctgcctcca tgccagcatc tgggggcaag gaaggctggc atcatccagt gaggaggctg
2461 gcgcatgttg ggaggctgct ggctgcacag acccgtgagg ggaggagagg ggctgctgtg
2521 caggggtgtg gagtagggag ctggctcccc tgagagccat gcagggcgtc tgcagcccag
2581 gcctctggca gcagctcttt gcccatctct ttggacagtg gccaccctgc acaatggggc
2641 cgacgaggcc tagggccctc ctacctgctt acaatttgga aaagtgtggc cgggtgcggt
2701 ggctcacgcc tgtaatccca gcactttggg aggccaaggc aggaggatcg ctggagccca
2761 gtaggtcaag accagccagg gcaacatgat gagaccctgt ctctgccaaa aaatttttta
2821 aactattagc ctggcgtggt agcgcacgcc tgtggtccca gctgctgggg aggctgaagt
2881 aggaggatca tttatgcttg ggaggtcgag gctgcagtga gtcatgattg tatgactgca
2941 ctccagcctg ggtgacagag caagaccctg tttcaaaaag aaaaaccctg ggaaaagtga
3001 agtatggctg taagtctcat ggttcagtcc tagcaagaag cgagaattct gagatcctcc
3061 agaaagtcga gcagcaccca cctccaacct cgggccagtg tcttcaggct ttactgggga
3121 cctgcgagct ggcctaatgt ggtggcctgc aagccaggcc atccctgggc gccacagacg
3181 agctccgagc caggtcaggc ttcggaggcc acaagctcag cctcaggccc aggcactgat
3241 tgtggcagag gggccactac ccaaggtcta gctaggccca agacctagtt acccagacag
3301 tgagaagccc ctggaaggca gaaaagttgg gagcatggca gacagggaag ggaaacattt
3361 tcagggaaaa gacatgtatc acatgtcttc agaagcaagt caggtttcat gtaaccgagt
3421 gtcctcttgc gtgtccaaaa gtagcccagg gctgtagcac aggcttcaca gtgattttgt
3481 gttcagccgt gagtcacact acatgccccc gtgaagctgg gcattggtga cgtccaggtt
3541 gtccttgagt aataaaaacg tatgttccct aaaaaaaaaa aaaggaattc
//