LOCUS HUMPDK3R 1599 bp mRNA linear HUM 30-NOV-1995
DEFINITION Homo sapiens pyruvate dehydrogenase kinase isoenzyme 3 (PDK3) mRNA,
complete cds.
ACCESSION L42452
VERSION L42452.1
KEYWORDS isoenzyme 3; pyruvate dehydrogenase kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1599)
AUTHORS Gudi,R., Bowker-Kinley,M.M., Kedishvili,N.Y., Zhao,Y. and
Popov,K.M.
TITLE Diversity of the pyruvate dehydrogenase kinase gene family in
humans
JOURNAL J. Biol. Chem. 270 (48), 28989-28994 (1995)
PUBMED 7499431
COMMENT Original source text: Homo sapiens male adult liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1599
/db_xref="H-InvDB:HIT000193813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="male"
/cell_type="hepatocyte"
/tissue_type="liver"
/dev_stage="adult"
gene 1..1599
/gene="PDK3"
mRNA 1..1599
/gene="PDK3"
5'UTR 1..23
/gene="PDK3"
CDS 23..1243
/gene="PDK3"
/note="isoenzyme 3"
/codon_start=1
/product="pyruvate dehydrogenase kinase"
/protein_id="AAC42011.1"
/translation="MRLFRWLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKT
SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDP
QVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRIS
FRMLINQHTLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPEL
EVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTL
GKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLY
ARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNP
SSEPRDASKYKAKQ"
3'UTR 1244..1599
/gene="PDK3"
BASE COUNT 466 a 326 c 357 g 450 t
ORIGIN
1 gtggtgcgcc gcccgggcga ggatgcggct gttccggtgg ctgctgaagc agccggtgcc
61 caagcagatc gagcgctact cgcgcttttc gccgtcgccg ctctccatca aacaattcct
121 ggacttcggg agagataatg catgtgagaa aacttcatat atgtttctac gaaaggaact
181 tcctgtgcgg ctggctaaca caatgagaga agttaatctt ctgccggata atttacttaa
241 ccgcccttca gtgggattgg ttcagagttg gtatatgcag agttttcttg aacttttaga
301 atatgaaaat aagagccctg aggatccaca ggtcttggat aactttctac aagttctgat
361 taaagtcaga aatagacaca atgatgtggt tcctacaatg gcacaaggag tgattgaata
421 caaggagaag tttgggtttg atcctttcat tagcactaac atccaatatt ttctggatcg
481 gttttatacc aaccgcatct ctttccgcat gcttattaat cagcacacac ttctgtttgg
541 gggtgacact aatcctgttc atcctaaaca cataggaagt atcgatccca cctgtaacgt
601 ggcggatgtg gtgaaagatg catatgaaac agccaagatg ctgtgtgaac agtattacct
661 ggtagctcca gagctggaag ttgaagaatt caatgccaaa gcgccagaca aacctattca
721 ggtggtttat gtgccctcac atctgtttca tatgctattt gagttgttca agaactcaat
781 gagagcgaca gttgaactct atgaagacag aaaagagggc taccctgctg ttaaaaccct
841 cgttactttg ggtaaagaag acttatccat taagatcagt gacctaggtg gtggtgtccc
901 acttcgaaaa atagatcgtc tttttaacta catgtattct actgctccta ggcccagcct
961 ggagcctacc agagctgccc ctttggctgg atttggttat ggtttgccaa tttcccgtct
1021 gtatgctaga tattttcaag gagatctgaa actgtattcc atggaaggag tgggtactga
1081 tgctgtcatt tatttgaagg ctctttcaag tgagtcattt gagagacttc cagtttttaa
1141 taagtccgca tggcgccatt acaagaccac gcctgaagcc gatgattgga gcaatcccag
1201 cagtgaaccc agggatgctt caaaatacaa agcaaaacag taatatacca ccttgatttc
1261 cattacaaag tatctgattt gtctgaataa aggtgtccca ctcactgttc caggaattct
1321 tgcagtgtag aggtattcac aacagcaagc agggatttgg cctgccatca attttattta
1381 aaaagcaatt aagtttgcag tttgtcctca taaacgttgt aggttgaaac tgaaaaataa
1441 gttaaaatga tcaatcaaga taaaaggtga tctatccatc caatggaata ttatttggcc
1501 ttaaaaagga aggacatctg atatgtgctg caacatgggt gaatcttgaa gtcattatgc
1561 taagtgaaat aaaccagaca taaaaggaca aatacatcg
//