LOCUS HUMPP2ABA 2448 bp mRNA linear HUM 09-SEP-1997
DEFINITION Homo sapiens protein phosphatase 2A B56-beta (PP2A) mRNA, complete
cds.
ACCESSION L42374
VERSION L42374.1
KEYWORDS B56-beta gene; protein phosphatase 2A B subunit; PP2A; B'/B56.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2448)
AUTHORS McCright,B. and Virshup,D.M.
TITLE Identification of a new family of protein phosphatase 2A regulatory
subunits
JOURNAL J. Biol. Chem. 270 (44), 26123-26128 (1995)
PUBMED 7592815
REFERENCE 2 (bases 1 to 2448)
AUTHORS McCright,B., Brothman,A.R. and Virshup,D.M.
TITLE Assignment of human protein phosphatase 2A regulatory subunit genes
b56alpha, b56beta, b56gamma, b56delta, and b56epsilon
(PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to
chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12
JOURNAL Genomics 36 (1), 168-170 (1996)
PUBMED 8812429
REFERENCE 3 (bases 1 to 2448)
AUTHORS Virshup,D.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-1997) HMBG, University of Utah, Bldg. 533, Rm
4480, Salt Lake City, UT 84112, USA
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2448
/db_xref="H-InvDB:HIT000193808"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..2448
/gene="PP2A"
mRNA 1..2448
/gene="PP2A"
5'UTR 1..325
/gene="PP2A"
CDS 326..1819
/gene="PP2A"
/note="similar to yeast RTS1"
/codon_start=1
/product="protein phosphatase 2A B56-beta"
/protein_id="AAC37602.1"
/translation="METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRS
HSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEV
KRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEP
SWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILH
RVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQ
FLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVM
FLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIED
NCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQE
QQKAQERQELWQGLEELRLRRLQGTQGAKEAPLQRLTPQVAASGGQS"
3'UTR 1820..2448
/gene="PP2A"
BASE COUNT 494 a 756 c 691 g 507 t
ORIGIN
1 ccgtcgccct ccctacgggc agcccccggg ggttggcgac cgaagtctag gttttcgaga
61 aagccagggt gggaacccta actggactct tcgggacccc caggaaggat ctgaggcctg
121 agccatcctc ctttctaccc tgtctgcccc ccaggactgg gcagttgcag gaggccctgg
181 gggggggccc aggactgtgg ttgtgccccc cccccaaagg ccggacagga tgggaccaag
241 ttagtctgtc cagtctcacc cagcacctcc caggcccaga gagaaccccc ggggctctga
301 aagcttgccc tgccgcctga ccgccatgga gacgaagctg ccccctgcaa gcacccccac
361 tagcccctcc tcccccgggc tgtcgcctgt gcccccaccc gacaaggtgg acggcttctc
421 ccgccgttcc ctccgcagag cccggccccg ccgctcccac agctcctctc agttccgcta
481 tcagagcaac cagcaagagc tcacaccgct gcccctgctc aaagatgtgc cggcttccga
541 gctgcacgag ctgctgagcc ggaagctggc ccagtgtggg gtgatgtttg acttcttgga
601 ctgtgtggcc gacctcaagg ggaaggaggt gaagcgggca gccctcaacg agctggtgga
661 gtgtgtgggg agcacccggg gtgtcctcat cgagcccgtc tacccagaca tcatccgcat
721 gatctcagtg aatatcttcc ggactctgcc gcccagtgag aaccctgaat ttgaccctga
781 agaggatgag cccaatcttg agccttcgtg gccacacctg cagctggtat atgagttttt
841 cctgcgtttc ttggagagcc cagacttcca gccctccgtg gccaagagat atgtggatca
901 aaagtttgtc ctgatgctcc tggagctatt tgatagtgag gatccccggg agcgtgagta
961 cctcaagacc atcctgcacc gggtctatgg caagttcctg ggtctccggg cctacatccg
1021 caaacagtgc aaccacatct tcctccggtt catctatgaa ttcgagcact tcaatggtgt
1081 ggctgagctg ctggagatcc taggaagcat catcaatggc tttgcgctgc ccctgaagac
1141 ggagcacaag cagttcctgg ttcgcgtcct gatccccctg cactctgtca agtcgctgtc
1201 tgtcttccat gcccagctgg catactgtgt ggtgcagttc ctggagaagg atgccactct
1261 gacagagcac gtgatccggg ggctgctcaa atactggcca aaaacctgca cccagaagga
1321 ggtgatgttt ctgggggaga tggaagagat tcttgatgtc atcgagccct cccagtttgt
1381 gaagatccag gagccccttt ttaagcaggt ggctcgctgt gtttccagcc cccatttcca
1441 ggttgcagag cgggctctgt atttctggaa caatgagtat atcctaagcc tcattgagga
1501 caactgccac actgtgctgc ctgctgtgtt tgggaccctc taccaagtct ccaaggagca
1561 ctggaaccaa accatcgtat cactgatcta caatgtgctc aagaccttca tggagatgaa
1621 tgggaagctg tttgatgagc tcacagcctc ctacaagctg gaaaagcagc aggagcagca
1681 gaaggcccag gagcgtcagg agttatggca aggtctggag gagctgcggc tacgccggct
1741 acaggggacc cagggggcca aggaggcccc cctccagcgg cttacacccc aggtggccgc
1801 cagtgggggt cagagctaga cagcacctca gaaggggaaa agctaaaccc agagctgtca
1861 gtccctctat cccttctcct gtccaggggc ccagagagaa acacacctac ccctggcctt
1921 gccagagtgg cttctgagga ctcccagccc agcccagctt tcactggggg gagacgagga
1981 gaggcaatgg tggtcttggc aacagaatgc tcagcccctc gtggcaggac ttgacaaggg
2041 caagcttgac caggaagctg ccatcaggga tcttcccctg ccccgcaaag ctaggctcca
2101 gctgcaggcg ggctcccacc ctctgctcct ggccttgggc aagggcactc agcgcctcgc
2161 ctgcccctgc cttggccaat gcgaggtcct tccttatccc caccatgggg tccatggtct
2221 atttattctc gcccagctca ccctctacac agacactgtc ctgggtgcac actcctccct
2281 tccctcgctg tgtacttcct tgtccccttt ttatttattg ggcaggggga gggggagggc
2341 acaggcaaga agagattcac agtgtcctgg ggtaaggggg ggttcacagt aatcatggtc
2401 tactcctctt tccgtggctg ggggtagact taataaagag agaaattc
//