LOCUS HUMIFNAK 2479 bp mRNA linear HUM 05-APR-1996
DEFINITION Homo sapiens interferon receptor ifnar2-3 (splice variant IFNAR2-3)
mRNA, complete cds.
ACCESSION L41943
VERSION L41943.1
KEYWORDS cytokine receptor; helical cytokine receptor family; hematopoietin
receptor family; interferon receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2479)
AUTHORS Lutfalla,G., Holland,S.J., Cinato,E., Monneron,D., Reboul,J.,
Rogers,N.C., Smith,J.M., Stark,G.R., Gardiner,K., Mogensen,K.E.,
Kerr,I.M. and Uze,G.
TITLE Mutant U5A cells are complemented by an interferon-alpha beta
receptor subunit generated by alternative processing of a new
member of a cytokine receptor gene cluster
JOURNAL EMBO J. 14 (20), 5100-5108 (1995)
PUBMED 7588638
COMMENT Original source text: Homo sapiens lymphoblastoid cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2479
/db_xref="H-InvDB:HIT000193795"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="21q22.1"
/cell_line="Daudi"
/cell_type="B"
/tissue_type="lymphoblastoid"
gene 1..2479
/gene="IFNAR2"
mRNA 1..2479
/gene="IFNAR2"
/note="splice variant IFNAR2-3"
5'UTR 1..39
/gene="IFNAR2"
CDS 40..759
/gene="IFNAR2"
/standard_name="ifnar2-3"
/note="splice variant IFNAR2-3"
/codon_start=1
/product="interferon receptor"
/protein_id="AAB46414.1"
/translation="MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKIS
LRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRST
HEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEE
ELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQ
AVIKSPLKCTLLPPGQESEFS"
3'UTR 760..2479
/gene="IFNAR2"
BASE COUNT 677 a 549 c 605 g 648 t
ORIGIN
1 agatgtaaaa gtcaagagaa gactctaaaa atagcaaaga tgcttttgag ccagaatgcc
61 ttcatcttca gatcacttaa tttggttctc atggtgtata tcagcctcgt gtttggtatt
121 tcatatgatt cgcctgatta cacagatgaa tcttgcactt tcaagatatc attgcgaaat
181 ttccggtcca tcttatcatg ggaattaaaa aaccactcca ttgtaccaac tcactataca
241 ttgctgtata caatcatgag taaaccagaa gatttgaagg tggttaagaa ctgtgcaaat
301 accacaagat cattttgtga cctcacagat gagtggagaa gcacacacga ggcctatgtc
361 accgtcctag aaggattcag cgggaacaca acgttgttca gttgctcaca caatttctgg
421 ctggccatag acatgtcttt tgaaccacca gagtttgaga ttgttggttt taccaaccac
481 attaatgtga tggtgaaatt tccatctatt gttgaggaag aattacagtt tgatttatct
541 ctcgtcattg aagaacagtc agagggaatt gttaagaagc ataaacccga aataaaagga
601 aacatgagtg gaaatttcac ctatatcatt gacaagttaa ttccaaacac gaactactgt
661 gtatctgttt atttagagca cagtgatgag caagcagtaa taaagtctcc cttaaaatgc
721 accctccttc cacctggcca ggaatcagaa ttttcataac tttttagcct ggccatttcc
781 taacctgcca ccgttggaag ccatggatat ggtggaggtc atttacatca acagaaagaa
841 gaaagtgtgg gattataatt atgatgatga aagtgatagc gatactgagg cagcgcccag
901 gacaagtggc ggtggctata ccatgcatgg actgactgtc aggcctctgg gtcaggcctc
961 tgccacctct acagaatccc agttgataga cccggagtcc gaggaggagc ctgacctgcc
1021 tgaggttgat gtggagctcc ccacgatgcc aaaggacagc cctcagcagt tggaactctt
1081 gagtgggccc tgtgagagga gaaagagtcc actccaggac ccttttcccg aagaggacta
1141 cagctccacg gaggggtctg ggggcagaat taccttcaat gtggacttaa actctgtgtt
1201 tttgagagtt cttgatgacg aggacagtga cgacttagaa gcccctctga tgctatcgtc
1261 tcatctggaa gagatggttg acccagagga tcctgataat gtgcaatcaa accatttgct
1321 ggccagcggg gaagggacac agccaacctt tcccagcccc tcttcagagg gcctgtggtc
1381 cgaagatgct ccatctgatc aaagtgacac ttctgagtca gatgttgacc ttggggatgg
1441 ttatataatg agatgactcc aaaactattg aatgaacttg gacagacaag cacctacagg
1501 gttctttgtc tctgcatcct aacttgctgc cttatcgtct gcaagtgttc tccaagggaa
1561 ggaggaggaa actgtggtgt tcctttcttc caggtgacat cacctatgca cattcccagt
1621 atggggacca tagtatcatt cagtgcattg tttacatatt caaagtggtg cactttgaag
1681 gaagcacatg tgcacctttc ctttacacta atgcacttag gatgtttctg catcatgtct
1741 accagggagc agggttcccc acagtttcag aggtggtcca ggaccctatg atatttctct
1801 tctttcgttc tttttttttt ttttttgaga cagagtctcg ttctgtcgcc caagctggag
1861 cgcaatggtg tgatcttggc tcactgcaac atccgcctcc cgggttcagg tgattctcct
1921 gcctcagcct ccctcgcaag tagctgggat tacaggcgcc tgccaccatg cctagcaaat
1981 ttttgtattt ttagtggaga caggatttta ccatgttggc caggctggtc tcgaactcct
2041 gacctcaagt gatctgccct cctcagcctc gtaaagtgct gggattacag gggtgagccg
2101 ctgtgcctgg ctggccctgt gatatttctg tgaaataaat tgggccaggg tgggagcagg
2161 gaaagaaaag gaaaatagta gcaagagctg caaagcaggc aggaagggag gaggagagcc
2221 aggtgagcag tggagagaag gggggccctg cacaaggaaa cagggaagag ccatcgaagt
2281 ttcagtcggt gagccttggg cacctcaccc atgtcacatc ctgtctcctg caattggaat
2341 tccaccttgt ccagccctcc ccagttaaag tggggaagac agactttagg atcacgtgtg
2401 tgactaatac agaaaggaaa catggcgtcg gggagaggga taaaacctga atgccatatt
2461 ttaagttaaa aaaaaaaaa
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