LOCUS HUMIFNAJ 2897 bp mRNA linear HUM 05-APR-1996
DEFINITION Homo sapiens interferon receptor ifnar2-2 (splice variant IFNAR2-2)
mRNA, complete cds.
ACCESSION L41942
VERSION L41942.1
KEYWORDS cytokine receptor; helical cytokine receptor family; hematopoietin
receptor family; interferon receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2897)
AUTHORS Lutfalla,G., Holland,S.J., Cinato,E., Monneron,D., Reboul,J.,
Rogers,N.C., Smith,J.M., Stark,G.R., Gardiner,K., Mogensen,K.E.,
Kerr,I.M. and Uze,G.
TITLE Mutant U5A cells are complemented by an interferon-alpha beta
receptor subunit generated by alternative processing of a new
member of a cytokine receptor gene cluster
JOURNAL EMBO J. 14 (20), 5100-5108 (1995)
PUBMED 7588638
COMMENT Original source text: Homo sapiens lymphoblastoid cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2897
/db_xref="H-InvDB:HIT000193794"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="21q22.1"
/cell_line="Daudi"
/cell_type="B"
/tissue_type="lymphoblastoid"
gene 1..2897
/gene="IFNAR2"
mRNA 1..2897
/gene="IFNAR2"
/note="splice variant IFNAR2-2"
5'UTR 1..326
/gene="IFNAR2"
CDS 327..1874
/gene="IFNAR2"
/standard_name="ifnar2-2"
/note="splice variant IFNAR2-2"
/codon_start=1
/product="interferon receptor"
/protein_id="AAB46413.1"
/translation="MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKIS
LRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRST
HEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEE
ELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQ
AVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSL
PKVLNFHNFLAWPFPNLPPLEAMDMVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSG
GGYTMHGLTVRPLGQASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLS
GPCERRKSPLQDPFPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLS
SHLEEMVDPEDPDNVQSNHLLASGEGTQPTFPSPSSEGLWSEDAPSDQSDTSESDVDL
GDGYIMR"
3'UTR 1875..2897
/gene="IFNAR2"
BASE COUNT 771 a 674 c 719 g 733 t
ORIGIN
1 cccgcactaa agacgcttct tcccggcggg taggaatccc gccggcgagc cgaacagttc
61 cccgagcgca gcccgcggac caccacccgg ccgcacgggc cgcttttgtc ccccgcccgc
121 cgcttctgtc cgagaggccg cccgcgaggc gcatcctgac cgcgagcgtc gggtcccaga
181 gccgggcgcg gctggggccc gaggctagca tctctcggga gccgcaaggc gagagctgca
241 aagtttaatt agacacttca gaattttgat cacctaatgt tgatttcaga tgtaaaagtc
301 aagagaagac tctaaaaata gcaaagatgc ttttgagcca gaatgccttc atcttcagat
361 cacttaattt ggttctcatg gtgtatatca gcctcgtgtt tggtatttca tatgattcgc
421 ctgattacac agatgaatct tgcactttca agatatcatt gcgaaatttc cggtccatct
481 tatcatggga attaaaaaac cactccattg taccaactca ctatacattg ctgtatacaa
541 tcatgagtaa accagaagat ttgaaggtgg ttaagaactg tgcaaatacc acaagatcat
601 tttgtgacct cacagatgag tggagaagca cacacgaggc ctatgtcacc gtcctagaag
661 gattcagcgg gaacacaacg ttgttcagtt gctcacacaa tttctggctg gccatagaca
721 tgtcttttga accaccagag tttgagattg ttggttttac caaccacatt aatgtgatgg
781 tgaaatttcc atctattgtt gaggaagaat tacagtttga tttatctctc gtcattgaag
841 aacagtcaga gggaattgtt aagaagcata aacccgaaat aaaaggaaac atgagtggaa
901 atttcaccta tatcattgac aagttaattc caaacacgaa ctactgtgta tctgtttatt
961 tagagcacag tgatgagcaa gcagtaataa agtctccctt aaaatgcacc ctccttccac
1021 ctggccagga atcagaatca gcagaatctg ccaaaatagg aggaataatt actgtgtttt
1081 tgatagcatt ggtcttgaca agcaccatag tgacactgaa atggattggt tatatatgct
1141 taagaaatag cctccccaaa gtcttgaatt ttcataactt tttagcctgg ccatttccta
1201 acctgccacc gttggaagcc atggatatgg tggaggtcat ttacatcaac agaaagaaga
1261 aagtgtggga ttataattat gatgatgaaa gtgatagcga tactgaggca gcgcccagga
1321 caagtggcgg tggctatacc atgcatggac tgactgtcag gcctctgggt caggcctctg
1381 ccacctctac agaatcccag ttgatagacc cggagtccga ggaggagcct gacctgcctg
1441 aggttgatgt ggagctcccc acgatgccaa aggacagccc tcagcagttg gaactcttga
1501 gtgggccctg tgagaggaga aagagtccac tccaggaccc ttttcccgaa gaggactaca
1561 gctccacgga ggggtctggg ggcagaatta ccttcaatgt ggacttaaac tctgtgtttt
1621 tgagagttct tgatgacgag gacagtgacg acttagaagc ccctctgatg ctatcgtctc
1681 atctggaaga gatggttgac ccagaggatc ctgataatgt gcaatcaaac catttgctgg
1741 ccagcgggga agggacacag ccaacctttc ccagcccctc ttcagagggc ctgtggtccg
1801 aagatgctcc atctgatcaa agtgacactt ctgagtcaga tgttgacctt ggggatggtt
1861 atataatgag atgactccaa aactattgaa tgaacttgga cagacaagca cctacagggt
1921 tctttgtctc tgcatcctaa cttgctgcct tatcgtctgc aagtgttctc caagggaagg
1981 aggaggaaac tgtggtgttc ctttcttcca ggtgacatca cctatgcaca ttcccagtat
2041 ggggaccata gtatcattca gtgcattgtt tacatattca aagtggtgca ctttgaagga
2101 agcacatgtg cacctttcct ttacactaat gcacttagga tgtttctgca tcatgtctac
2161 cagggagcag ggttccccac agtttcagag gtggtccagg accctatgat atttctcttc
2221 tttcgttctt tttttttttt ttttgagaca gagtctcgtt ctgtcgccca agctggagcg
2281 caatggtgtg atcttggctc actgcaacat ccgcctcccg ggttcaggtg attctcctgc
2341 ctcagcctcc ctcgcaagta gctgggatta caggcgcctg ccaccatgcc tagcaaattt
2401 ttgtattttt agtggagaca ggattttacc atgttggcca ggctggtctc gaactcctga
2461 cctcaagtga tctgccctcc tcagcctcgt aaagtgctgg gattacaggg gtgagccgct
2521 gtgcctggct ggccctgtga tatttctgtg aaataaattg ggccagggtg ggagcaggga
2581 aagaaaagga aaatagtagc aagagctgca aagcaggcag gaagggagga ggagagccag
2641 gtgagcagtg gagagaaggg gggccctgca caaggaaaca gggaagagcc atcgaagttt
2701 cagtcggtga gccttgggca cctcacccat gtcacatcct gtctcctgca attggaattc
2761 caccttgtcc agccctcccc agttaaagtg gggaagacag actttaggat cacgtgtgtg
2821 actaatacag aaaggaaaca tggcgtcggg gagagggata aaacctgaat gccatatttt
2881 aagttaaaaa aaaaaaa
//