LOCUS HUMPLCB4M 3707 bp mRNA linear HUM 05-JUN-1996
DEFINITION Homo sapiens phospholipase C beta 4 (PLCB4) mRNA, complete cds.
ACCESSION L41349
VERSION L41349.1
KEYWORDS phospholipase C-beta4.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3707)
AUTHORS Alvarez,R.A., Ghalayini,A.J., Xu,P., Hardcastle,A.,
Bhattacharya,S., Rao,P.N., Pettenati,M.J., Anderson,R.E. and
Baehr,W.
TITLE cDNA sequence and gene locus of the human retinal
phosphoinositide-specific phospholipase-C beta 4 (PLCB4)
JOURNAL Genomics 29 (1), 53-61 (1995)
PUBMED 8530101
REFERENCE 2 (bases 1 to 3707)
AUTHORS Alvarez,R.A.
TITLE Direct Submission
JOURNAL Submitted (06-APR-1995) Richard A. Alvarez, Ophthalmology, Univ.
Oklahoma, Oklahoma City, OK 73104, USA
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3707
/db_xref="H-InvDB:HIT000193761"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="retina"
/dev_stage="fetus"
gene 1..3707
/gene="PLCB4"
mRNA 1..>3707
/gene="PLCB4"
5'UTR 1..230
/gene="PLCB4"
CDS 231..3299
/gene="PLCB4"
/function="hydrolysis of pip2"
/standard_name="PLCb4"
/note="putative"
/codon_start=1
/product="phospholipase C beta 4"
/protein_id="AAB02027.1"
/translation="MNNNWNVCFFLFCPSITRTFASGKTEKVIFQALKELGLPSGKND
EIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRL
NEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQ
EMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEP
IITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFG
DLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESA
SPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLVTVEDE
QAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGY
LKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLN
QGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIG
TYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESLVFRKVILPDLAVLRIAVYDD
NNKLIGQRIPPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDAL
SDPKTFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSEL
RPTTTAALPSGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHS
TMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDH
KSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKL
SHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRL
AMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV"
3'UTR 3300..>3707
/gene="PLCB4"
BASE COUNT 1263 a 757 c 793 g 894 t
ORIGIN
1 gtgtgtccct ccagtgccgc ttgccccttg ttctcccaag caccaggggg acccctgtct
61 tagattcaag ttgcatcact agactaacag ctctgggaac agaggacact gaggactagt
121 ttgggaaatg aaaaacatct gcaatgagag gtaattttat tctcctcttc cttttaccct
181 agtctcactc tccatagtag gacctggatc tttgcatcag agaaaacata atgaacaata
241 actggaatgt gtgtttcttt cttttctgcc ctagtattac tagaacattt gcatcgggaa
301 aaacagaaaa ggtgatcttt caagcactca aggagttagg tcttcccagt ggaaagaatg
361 atgaaattga gcccacagca ttttcttatg aaaagttcta tgaactgaca caaaagattt
421 gtcctcggac agatatagaa gatcttttca aaaaaatcaa tggagacaaa actgattatt
481 taacggtaga ccaattagtg agctttctaa atgaacatca acgagatcct cgattgaatg
541 aaattttatt tccattttat gatgccaaaa gggcaatgca gatcattgag atgtatgaac
601 ctgatgaaga tttgaagaaa aaaggcctta tatcaagtga tgggttttgc agatatctga
661 tgtcagatga aaacgcccca gtcttcctag atcgtttaga actttaccaa gaaatggacc
721 atcctctggc tcactacttc atcagttctt cccataacac ttatctcact ggcagacagt
781 tcggcgggaa gtcttcggta gaaatgtaca gacaggttct cctggctggt tgcagatgtg
841 ttgaacttga ctgctgggat ggaaaaggtg aggaccaaga accaataata actcatggaa
901 aagcaatgtg tacagatatc ctttttaagg atgtaattca agccatcaag gaaactgcat
961 ttgtcacatc agaatatcct gtaattctct cctttgaaaa tcactgcagc aaatatcaac
1021 agtacaagat gtccaaatat tgcgaagatc tatttgggga tctcctgttg aaacaagcac
1081 ttgaatcaca tccactggaa ccaggcagac ctttgccatc ccccaatgac ctcaaaagaa
1141 aaatactcat aaaaaacaag cggctgaaac ctgaagttga aaaaaaacag ctggaagctt
1201 tgagaagcat gatggaagct ggagaatctg cctccccagc aaacatctta gaggacgata
1261 atgaagagga gatcgaaagt gctgaccaag aggaggaagc tcaccccgaa ttcaaatttg
1321 gaaatgaact ttctgctgat gacttgggtc acaaggaagc tgttgcaaat agcgtcaaga
1381 agggcctggt cactgtagaa gatgagcagg cgtggatggc atcttataaa tatgtaggtg
1441 ctaccactaa tatccatcca tatttgtcca caatgatcaa ctatgcccag cctgtaaagt
1501 ttcaaggttt ccatgtggca gaagaacgca atattcatta taacatgtct tcttttaatg
1561 aatcagtcgg tcttggctac ttgaagacac atgcaattga atttgtcaat tataacaaac
1621 ggcaaatgag tcgcatttac cccaagggag gccgagtcga ttccagtaat tacatgcctc
1681 agattttctg gaacgctggc tgccagatgg tttcactgaa ctatcaaacc ccagatttag
1741 cgatgcaatt gaatcaggga aaatttgagt ataatggatc gtgcgggtac cttctcaaac
1801 cagatttcat gaggcggcct gatcgaacat ttgacccctt ctctgaaacg cctgttgatg
1861 gggttattgc agccacttgc tcagtgcagg ttatatcagg tcaattctta tcagataaga
1921 aaattggcac ctacgtagag gtggatatgt atgggttgcc cactgacacc atacgtaagg
1981 aattccgaac tcgcatggtt atgaataatg gactcaatcc agtttacaat gaagagtcac
2041 ttgtatttcg gaaggtgatc ctgccggacc tggctgtctt gagaatagct gtgtatgatg
2101 ataacaacaa gctgattggc cagaggattc ctccgcttga tggcctccaa gccggatatc
2161 gacacatttc ccttcgaaat gagggaaata aaccattatc actaccaaca attttctgca
2221 atattgttct taaaacatat gtgcctgatg gatttggaga tatcgtggat gctttatcag
2281 atccaaagac atttctctca attacagaaa agagagcaga ccaaatgaga gctatgggca
2341 ttgagactag tgacatagcc gacgtgccca gtgacacttc caaaaatgac aagaaaggaa
2401 aggccaacac cgccaaagca aatgtgaccc ctcagagtag ctctgagctc agaccaacca
2461 ccacggctgc cctgccgtct ggtgtggaag ccaagaaagg tattgaactt atccctcaag
2521 taaggataga agacttaaag cagatgaagg cttacttgaa gcatttaaag aaacagcaga
2581 aggagctaaa ttctttaaag aagaaacatg caaaggaaca cagtaccatg cagaagttac
2641 actgcacgca agttgacaaa attgtggcac agtatgacaa agagaagtcg actcatgaga
2701 aaatcctaga gaaggcaatg aagaagaaag ggggaagtaa ttgtcttgaa atgaagaaag
2761 aaacagaaat taaaattcag acgctgacat cagatcacaa atctaaggtc aaggagattg
2821 tagcacagca cacaaaggaa tggtcagaaa tgatcaatac tcacagtgct gaggagcaag
2881 aaatccgaga cctgcacctc agccagcagt gtgagctgct gaaaaagcta ctcatcaatg
2941 cccacgagca gcaaacccag cagctgaaac tgtcccatga cagggaaagc aaggaaatgc
3001 gagcacacca ggctaagatt tctatggaaa atagcaaagc catcagccaa gataaatcta
3061 tcaagaataa agcagaacgg gaaaggcgag tcagggagtt aaacagcagc aacactaaaa
3121 agtttctgga agaaagaaag agacttgcca tgaagcagtc caaagaaatg gatcagttga
3181 aaaaagtcca gcttgaacat ctagaattcc tagagaaaca gaatgagcag gcgaaggaga
3241 tgcagcagat ggtgaaattg gaagccgaga tggaccgcag accagcaaca gtagtatgaa
3301 actccaaaat gcaaactgaa gcagcaaacc cacaaagcat caaaagactc actcacaaaa
3361 cttctgaaca caaactccat ggatgaaagc tgtttatttt gtttccttta tgtgtaaaca
3421 agatgatatc tgaaaccaga gagacttgga atgtctgact gacttctatt taacagcttg
3481 agtattgcat ttccttggcc aaacaaaaat agctacaaat ccacaaaaat ttactattcc
3541 agtaaggcag agtccaacca ttgataatac aacttaaaca tgtttgctat aaaataccat
3601 cacaagtaaa tgagcttggt gtgaacaact cttcctttgt gatgccttag gacatgttgt
3661 aactgcaggc aaaacaaaca aaacagtgca ttagcaattt catagca
//