LOCUS HUMTRIP9G 1940 bp DNA linear HUM 15-MAR-1995
DEFINITION Homo sapiens thyroid receptor interactor (TRIP9) gene, complete
cds.
ACCESSION L40407
VERSION L40407.1
KEYWORDS TRIP9 gene; thyroid receptor interactor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1940)
AUTHORS Lee,J.W., Choi,H.S., Gyuris,J., Brent,R. and Moore,D.D.
TITLE Two classes of proteins dependent on either the presence or absence
of thyroid hormone for interaction with the thyroid hormone
receptor
JOURNAL Mol. Endocrinol. 9 (2), 243-254 (1995)
PUBMED 7776974
COMMENT Trip9 was isolated as interacting with the thyroid hormone receptor
in
the yeast 2-hybrid system. Interaction is dependent on the
presence of
hormone. Submitted sequence is full length or nearly full length
at
the 5' end and includes the apparently complete protein coding
region.
The fusion junction in the original yeast 2-hybrid isolate is at
position 569. Trip9 includes 6 copies of the motif commonly
referred
to as the ankyrin repeat. Two mRNAs of approximate 1.8 and 2.8 kb
are
detected by Northern blotting.
FEATURES Location/Qualifiers
source 1..1940
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/cell_line="Hela"
gene 53..1069
/gene="TRIP9"
CDS 53..1069
/gene="TRIP9"
/codon_start=1
/product="thyroid receptor interactor"
/protein_id="AAC41742.1"
/translation="MAGVACLGKAADADEWCDTGLGSLGPDAAAPGGPGLGAELGPGL
SWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAA
ILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDT
YLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHK
DVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRT
PLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDGGDEGVSQEERQGSPA
GGSG"
BASE COUNT 420 a 526 c 678 g 316 t
ORIGIN
1 aaagccagct acaggcgggc gactgcgggg ggcccctgag gcggcggggg ccatggctgg
61 ggtcgcgtgc ttgggaaaag ctgccgacgc agatgaatgg tgcgacacgg gcctgggctc
121 cctgggtccg gacgcagcgg cccccggagg acctgggttg ggcgcggagt tgggcccggg
181 gctgtcgtgg gctcccctcg tcttcggcta cgtcactgag gatggggaca cggcactgca
241 cttggctgtg attcatcagc atgaaccctt cctggatttt cttctaggct tctcggccgg
301 cactgagtac atggacctgc agaatgacct aggccagaca gccctgcacc tggcagccat
361 cctgggggag acatccacgg tggagaagct gtacgcagca ggcgccgggc tgtgtgtggc
421 ggagcgtagg ggccacacgg cgctgcacct ggcctgccgt gtgggggcac acgcctgtgc
481 ccgtgccctg cttcagcccc gcccccggcg ccccagggaa gcccccgaca cctacctcgc
541 tcagggccct gaccgtactc ccgacaccaa ccatacccct gtcgccttgt accccgattc
601 cgacttggag aaggaagaag aggagagtga ggaggactgg aagctgcagc tggaggctga
661 aaactacgag ggccacaccc cactccacgt ggccgttatc cacaaagatg tggagatggt
721 ccggctgctc cgagatgctg gagctgacct tgacaaaccg gagcccacgt gcggccggag
781 cccccttcat ttggcagtgg aggcccaggc agccgatgtg ctggagcttc tcctgagggc
841 aggcgcgaac cctgctgccc gcatgtacgg tggccgcacc ccactcggca gtgccatgct
901 ccggcccaac cccatcctcg cccgcctcct ccgtgcacac ggagcccctg agcccgaggg
961 cgaggatgag aaatccggcc cctgcagcag cagtagcgac agcgacggcg gagacgaggg
1021 cgtgagtcag gaggagagac agggcagccc agctgggggg tcaggataga ccggcagcaa
1081 gaagcccaag aagataatta ggcaccgacc ttgggctgct gttagagaac tcaggcggca
1141 cgccagtgac acggggcact agtcaggaga gacctggaca ggggtggtgg gaagagcttg
1201 ggcagaagtg gctgaaaaac taaggcagtg gcaaaggtag aactcaggca ggggtggaga
1261 aaagcgttgg tcgcagtgat tggtgaacac agcgggggtg ggtggtagcg ctgggggtga
1321 ttttaggcag caagaattgg agaactcaca ctgcgaaaag aaaaccttgg gtggcagtga
1381 tttgaacacc ggcagtgctg gggcaggacc cgagccagcg gtggggagag atatagtcag
1441 agaacccagc aatacagatc cgtccttggg caaggcgcgg tgctggatga tgggtgcgga
1501 ggaatttggg taaaggcaga gggaaggggt ggaggagggc cagctcagtt gccgaaactc
1561 tggagtggcg gctggctaga aattggtctg tagaaatgac cttgaaaatg gagttctggc
1621 caggtgcggt ggctcacgcc tgtaatccca gcactttggg aggccgaggc aggcagatca
1681 cgaggtcagg agttcgagac cagcctggcc aacatggcaa gaccctgtct ctactaaaaa
1741 tacaaaaatt agctgggcgt ggtggcgcat gcctataatc ccagctactt gggaggctga
1801 ggtaggagaa ttgcttgaac ctgggaggtg gaggttgcag tgaacctaga tcacgccact
1861 gcattccagc ctgggcaaca gagcgcatga tcagtcaacc gctcgaggga tcttccatag
1921 gatggtcaag acgcggacgt
//