LOCUS HUMEEAP 5028 bp mRNA linear HUM 10-OCT-1995
DEFINITION Human endosome-associated protein (EEA1) mRNA, complete cds.
ACCESSION L40157
VERSION L40157.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5028)
AUTHORS Mu,F.T., Callaghan,J.M., Steele-Mortimer,O., Stenmark,H.,
Parton,R.G., Campbell,P.L., McCluskey,J., Yeo,J.P., Tock,E.P. and
Toh,B.H.
TITLE EEA1, an early endosome-associated protein. EEA1 is a conserved
alpha-helical peripheral membrane protein flanked by cysteine
'fingers' and contains a calmodulin-binding IQ motif
JOURNAL J. Biol. Chem. 270 (22), 13503-13511 (1995)
PUBMED 7768953
COMMENT On Oct 10, 1995 this sequence version replaced gi:790791.
Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..5028
/db_xref="H-InvDB:HIT000193591"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pFM9.9"
/cell_line="HeLa"
/note="vector Lambda gt-11"
gene 1..5028
/gene="EEA1"
CDS 137..4369
/gene="EEA1"
/codon_start=1
/product="endosome-associated protein"
/protein_id="AAA79121.1"
/translation="MLRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICP
QCMKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEE
KWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDL
FEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRP
GIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLRSEL
SKGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKN
IQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLK
AEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD
KEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQ
NDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQL
QEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVN
ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQE
LNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSL
EVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESI
KQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELS
TVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKE
LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKK
KQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQ
LQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLE
QDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE
LKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE
EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR
RVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL
DNTTAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGN
IFCAECSAKNALTPSSKKPVRVCDACFNDLQG"
BASE COUNT 1966 a 863 c 1049 g 1150 t
ORIGIN
1 gaattccggc cgctcggccc gacctccttc ccggtcccct cccggcccag tccctcccgc
61 ccgcccaccc cgagtagtga gtggccccgc gcaggtctgg agagtcaccg cggcgggccc
121 gggtggtggt taaaccatgt taaggaggat tttacagagg actcctggga gagttggctc
181 tcaaggttct gatttagatt catcagcaac tcctataaac acagtggacg tcaataatga
241 aagctcttca gaaggtttca tatgtcccca gtgtatgaaa tctcttggat ctgctgatga
301 acttttcaaa cattatgaag ctgttcatga tgctggtaat gactcaggtc atggaggaga
361 gtctaatctt gctttgaagc gagatgatgt aacactgctc agacaagagg tccaagacct
421 acaggcttca cttaaggaag aaaaatggta ctcggaagaa ttaaagaagg aattagaaaa
481 atatcaaggg ctgcagcagc aagaggccaa acctgatggg ttggtgactg attcatcagc
541 agaactacag tctttggaac agcaattaga agaagcccaa acagaaaatt ttaatattaa
601 gcaaatgaaa gacttatttg aacagaaagc agcccaactt gctactgaaa ttgcagatat
661 aaagtcaaag tatgatgaag aaaggagtct tcgagaagct gctgaacaaa aagtgacacg
721 tctgacagaa gaattaaaca aagaggcaac tgtaattcaa gatctgaaga cggaactgct
781 tcagagacct ggtatagaag atgttgccgt gctaaagaaa gaactggtcc aagttcaaac
841 actaatggat aacatgacct tggaacgtga gcgagaatct gaaaaactca aagatgaatc
901 gaaaaaattc gagtcacaat atgctagctc agaggccaca ataagccagc taaggagtga
961 actgtccaaa ggcccccagg aagttcgtgt atatgtacag gaactacaaa aactgaaaag
1021 ttcagttaat gaattaacac aaaaaaatca gaccttgaca gaaaacttgc tgaaaaaaga
1081 acaagactat actaagttag aggagaaaca taatgaagaa tctgtgagta aaaagaatat
1141 tcaggcaacc cttcatcaaa aagacctaga ttgtcaacag cttcagtcaa gattgtctgc
1201 atctgaaacc tcactgcata gaatacatgt agaactaagt gaaaaaggag aagctactca
1261 aaagctcaaa gaagaattat ctgaggtaga gaccaagtac cagcatctaa aggcggagtt
1321 taagcagcta caacaacaga gagaagaaaa ggagcagcat gggttacaac tccaaagtga
1381 aattaatcaa ttacatagca aacttctgga gacagagcgc caactagggg aagctcatgg
1441 taggctgaag gaacagagac agctttcaag tgaaaagttg atggataaag aacaacaagt
1501 ggctgattta caactcaaac tttctcggtt agaagagcag ttgaaggaaa aagttacaaa
1561 ttctacagaa ttgcagcatc aattagataa aacaaagcaa cagcatcaag aacaacaggc
1621 tcttcagcaa agcaccacgg caaaacttcg agaagctcag aatgatttgg aacaagttct
1681 acgtcaaatt ggcgaaaagg accaaaagat ccagaacctt gaagctttat tacagaagag
1741 taaagaaaat atttcattac tagaaaaaga aagagaagat ctttatgcaa aaattcaggc
1801 tggtgaagga gagactgctg ttcttaacca gttacaagaa aaaaaccata cactacagga
1861 cgaagtaact caactaacag agaacgtgaa gaatcagtca gaaagtcata aacaagccca
1921 ggagaatttg catgaccagg tacaagagca gaaggcacat cttagagctg cacaagaccg
1981 tgtcctttcc ctagaaacta gtgtcaatga attaaatagt caattaaatg aaagcaagga
2041 gaaggtctcc cagcttgaca tacagattaa agccaaaacc gaactattac tatcagcaga
2101 agcagcaaaa actgctcaaa gagctgatct tcagaatcat ttggacacag ctcaaaatgc
2161 attacaagat aaacaccagg agttaaataa gattactact cagttggatc aggtcactgc
2221 aaagttacaa gacaagcaag aacattgcag tcagctggaa agtcatctta aagaatataa
2281 agagaaatac ctctctttag aacagaaaac cgaagagcta gaaggtcaaa ttaagaaact
2341 agaagctgat agtcttgaag ttaaagcaag caaggagcag gctttgcaag atctacaaca
2401 gcaaagacag ctgaacacag atttagagct cagagccaca gaattgagta aacaacttga
2461 aatggagaag gaaatagtat ccagtacaag attggatcta cagaaaaaat ctgaagccct
2521 tgaaagtatc aagcaaaagc ttaccaagca agaggaagaa aaacaaatcc tgaaacaaga
2581 ttttgaaact ttaagtcaag aaacaaagat tcagcatgag gaattgaata acagaattca
2641 aacaacagta acagaactac aaaaagtgaa aatggagaaa gaagctttaa tgacagagct
2701 ttctacagta aaggacaaac tatcaaaagt ttctgattct ttgaaaaact ctaaaagtga
2761 atttgaaaag gagaatcaga aaggaaaagc cgctatatta gacttggaaa aaacttgcaa
2821 agaattaaag catcaacttc aagtgcagat ggaaaacaca cttaaggaac agaaggaact
2881 gaaaaagtca cttgaaaaag agaaggaggc ttctcatcag ttgaaattgg aactcaattc
2941 aatgcaggaa caacttatac aggcccagaa tactttaaaa caaaatgaaa aagaagagca
3001 acaacttcag gggaacataa atgagctaaa gcaatcaagt gaacagaaga aaaaacaaat
3061 tgaagcactc caaggagagc ttaaaattgc tgttttacag aagacagagc ttgagaataa
3121 actacagcag cagttaacac aggcagccca ggaacttgca gcagagaaag agaaaatatc
3181 agtattacaa aacaactatg aaaaaagtca ggaaactttc aaacagcttc aatctgattt
3241 ctatgggagg gaatctgaac ttctagccac caggcaagat cttaagtctg tagaagagaa
3301 gctttctcta gcacaggagg acttgatttc aaacagaaat caaattggaa atcaaaataa
3361 attgattcaa gaactgaaga ctgccaaggc tacattggag caggattcag caaagaaaga
3421 acagcaattg caggagcgat gtaaagcact acaagacatt cagaaagaaa agtcactgaa
3481 agaaaaagaa ctggtaaatg agaagtctaa attggcagag atagaagaaa ttaaatgtag
3541 acaagaaaaa gaaatcacta aactaaacga agaactcaag tcccacaaac tagaaagcat
3601 aaaggagata acaaatctta aagatgctaa acagcttcta attcagcaga aattagaact
3661 tcaaggaaaa gcggactccc tgaaggcagc tgttgaacag gagaagagaa atcagcagat
3721 actaaaagac caggtgaaaa aggaagaaga ggagctgaag aaagaattta ttgagaaaga
3781 agctaagttg cattccgaaa taaaagaaaa ggaagtagga atgaagaagc atgaagaaaa
3841 tgaggctaaa cttaccatgc agattacagc attaaatgaa aacttaggca ctgtgaagaa
3901 ggagtggcaa tctagtcaac ggagagttag tgagcttgag aaacaaacgg atgacttacg
3961 gggtgaaatt gcagtattag aagcaacggt tcagaataat caagatgaaa ggagagcact
4021 actggaaaga tgtcttaaag gagaaggtga aatagaaaag cttcaaacca aagtattaga
4081 attgcaaaga aagctggata atacaactgc agtgcaggag ctgggcagag aaaaccaatc
4141 acttcagatc aaacatacac aagcgttgaa tagaaagtgg gccgaagaca atgaagtaca
4201 aaactgtatg gcctgtggga aaggcttttc agtaacagtg agacggcatc actgccgaca
4261 gtgtggaaat atcttctgtg ctgaatgttc agccaaaaat gccttaactc cttcctccaa
4321 gaagcctgtt cgtgtctgtg atgcatgttt caatgacttg caaggataat gggttatcac
4381 aacttcagag taatattaca ctaacattag attttataat gtacttaata gaggtcttgg
4441 actactattt ggtttggaca cttggttgca atactagacc aaataggaat tagtatattt
4501 tggaatgtta tggatatcaa gtaaaactct tctatttttg tgagacttgg gcttatcatc
4561 tttcattact tttttcccat ttagcccctg gaatagcttt catgccaagt ttagaattag
4621 ccaatgaaat gtaaataaac tttggacaga aaatagcaat gtattttttt aatataattt
4681 cattattcac aaatgaagaa tgcaattcca tagcttactt ctttctccta aatttaatgt
4741 acaaaaatgt acatggatga tattatcact tgttgctgtt tttgcgacaa tagcacatta
4801 attatattaa atattctctt tgtgaagtta tgcacagaac tgtaacactt tcctctgcct
4861 ttttctctta tatgtgggtt catggttcag ttcgattgtt atgttatgaa tttactactt
4921 gggtgttcta aatacagttt atcttaaaat atgtagtaat atgaattcaa aaatggtttt
4981 tgttttaaca atattaatta aattttcttg ggtgatttta tggaattc
//