LOCUS HUMTRIP1M 1289 bp mRNA linear HUM 15-MAR-1995
DEFINITION Homo sapiens thyroid receptor interactor (TRIP1) mRNA, complete
cds.
ACCESSION L38810
VERSION L38810.1
KEYWORDS ATPase; TRIP1 gene; homologue; sug1 gene; thyroid receptor
interactor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1289)
AUTHORS Lee,J.W., Choi,H.S., Gyuris,J., Brent,R. and Moore,D.D.
TITLE Two classes of proteins dependent on either the presence or absence
of thyroid hormone for interaction with the thyroid hormone
receptor
JOURNAL Mol. Endocrinol. 9 (2), 243-254 (1995)
PUBMED 7776974
REFERENCE 2 (sites)
AUTHORS Lee,J.W., Ryan,F., Swaffield,J.C., Johnston,S.A. and Moore,D.D.
TITLE Interaction of thyroid-hormone receptor with a conserved
transcriptional mediator
JOURNAL Nature 374 (6517), 91-94 (1995)
PUBMED 7870181
COMMENT Original source text: Homo sapiens cDNA to mRNA.
Trip1 was isolated as interacting with the thyroid hormone receptor
in the
yeast two hybrid system. Interaction is dependent on the presence
of
thyroid hormone. Trip1 shares strong sequence similarity with the
yeast
transcriptional mediator SUG1 and contains a CAD region. Submitted
sequence is full length or nearly full length.
FEATURES Location/Qualifiers
source 1..1289
/db_xref="H-InvDB:HIT000193400"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1289
/gene="TRIP1"
mRNA <19..1289
/gene="TRIP1"
/product="thyroid receptor interactor"
CDS 19..1239
/gene="TRIP1"
/codon_start=1
/product="thyroid receptor interactor"
/protein_id="AAC41735.1"
/translation="MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRR
LQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKN
IDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKE
IKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSE
LVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGSSEVQRQMLEL
LNQLDGFEATKNIKVIMATNRIDMLDSALLRPGRIDRKIEFPPPNEEARLDILKIHSR
KMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQ
KDSEKNMSIKKLWK"
3'UTR 1240..1289
/gene="TRIP1"
regulatory 1267..1272
/regulatory_class="polyA_signal_sequence"
/gene="TRIP1"
/note="putative"
polyA_site 1289
/gene="TRIP1"
BASE COUNT 353 a 278 c 386 g 272 t
ORIGIN
1 tgctgctgaa gagagaagat ggcgcttgac ggaccagagc agatggagct ggaggagggg
61 aaggcaggca gcggactccg ccaatattat ctgtccaaga ttgaagaact ccagctgatt
121 gtgaatgata agagccaaaa cctccggagg ctgcaggcac agaggaacga actaaatgct
181 aaagttcgcc tattgcggga ggagctacag ctgctgcagg agcagggctc ctatgtgggg
241 gaagtagtcc gggccatgga taagaagaaa gtgttggtca aggtacatcc tgaaggtaaa
301 tttgttgtag acgtggacaa aaacattgac atcaatgatg tgacacccaa ttgccgggtg
361 gctctaagga atgacagcta cactctgcac aagatcctgc ccaacaaggt agacccatta
421 gtgtcactga tgatggtgga gaaagtacca gattcaactt atgagatgat tggtggactg
481 gacaaacaga tcaaggagat caaagaagtg atcgagctgc ctgttaagca tcctgagctc
541 ttcgaagcac tgggcattgc tcagcccaag ggagtgctgc tgtatggacc tccaggcact
601 gggaagacac tgttggcccg ggctgtggct catcatacgg actgtacctt tattcgtgtc
661 tctggctctg aattggtaca gaaattcata ggggaagggg caagaatggt gagggagctg
721 tttgtcatgg cacgggaaca tgctccatct atcatcttca tggacgaaat cgactccatc
781 ggctcctcgc ggctggaggg gggttctgga gggagcagtg aagtgcagcg ccagatgctg
841 gagttgctca accagctcga cggctttgag gccaccaaga acatcaaggt tatcatggct
901 actaatagga ttgatatgct ggactcggca ctgcttcgcc cagggcgcat tgacagaaaa
961 attgaattcc caccccccaa tgaggaggcc cggctggaca ttttgaagat tcattctcgg
1021 aagatgaacc tgacccgggg gatcaacctg agaaaaattg ctgagctcat gccaggagca
1081 tcaggggctg aagtgaaggg cgtgtgcacg gaagctggca tgtatgccct gcgagaacgg
1141 cgagtccatg tcactcagga ggactttgag atggcagtag ccaaggtcat gcagaaggac
1201 agtgagaaaa acatgtccat caagaaatta tggaagtgag tggacagcct ttgtgtgtat
1261 ctctccaata aagctctgtg ggccaagtc
//