LOCUS HUMHTK 1953 bp mRNA linear HUM 18-APR-1995
DEFINITION Homo sapiens hepatoma transmembrane kinase ligand (HTK ligand)
mRNA, complete cds.
ACCESSION L38734
VERSION L38734.1
KEYWORDS HTK ligand; hepatoma transmembrane receptor ligand; transmembrane
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1953)
AUTHORS Bennett,B.D., Zeigler,F.C., Gu,Q., Fendly,B., Goddard,A.D.,
Gillett,N. and Matthews,W.
TITLE Molecular cloning of a ligand for the EPH-related receptor
protein-tyrosine kinase Htk
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (6), 1866-1870 (1995)
PUBMED 7534404
COMMENT Original source text: Homo sapiens fetal brain cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1953
/db_xref="H-InvDB:HIT000193399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..1953
/gene="HTK"
mRNA 1..1953
/gene="HTK"
/product="hepatoma transmembrane kinase ligand"
CDS 32..1033
/gene="HTK"
/note="704..781 transmembrane domain"
/codon_start=1
/product="hepatoma transmembrane kinase ligand"
/protein_id="AAC41752.1"
/translation="MAVRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLP
GQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCA
KPDQDIKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKI
LMKVGQDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGN
NILGSEVALFAGIASGCIIFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPK
RSGNNNGSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV"
sig_peptide 32..115
/gene="HTK"
mat_peptide 116..1030
/gene="HTK"
/product="HTK ligand"
BASE COUNT 511 a 502 c 522 g 418 t
ORIGIN
1 ctcgaggcgc ggagctggga gtggcttcgc catggctgtg agaagggact ccgtgtggaa
61 gtactgctgg ggtgttttga tggttttatg cagaactgcg atttccaaat cgatagtttt
121 agagcctatc tattggaatt cctcgaactc caaatttcta cctggacaag gactggtact
181 atacccacag ataggagaca aattggatat tatttgcccc aaagtggact ctaaaactgt
241 tggccagtat gaatattata aagtttatat ggttgataaa gaccaagcag acagatgcac
301 tattaagaag gaaaataccc ctctcctcaa ctgtgccaaa ccagaccaag atatcaaatt
361 caccatcaag tttcaagaat tcagccctaa cctctggggt ctagaatttc agaagaacaa
421 agattattac attatatcta catcaaatgg gtctttggag ggcctggata accaggaggg
481 aggggtgtgc cagacaagag ccatgaagat cctcatgaaa gttggacaag atgcaagttc
541 tgctggatca accaggaata aagatccaac aagacgtcca gaactagaag ctggtacaaa
601 tggaagaagt tcgacaacaa gtccctttgt aaaaccaaat ccaggttcta gcacagacgg
661 caacagcgcc ggacattcgg ggaacaacat cctcggttcc gaagtggcct tatttgcagg
721 gattgcttca ggatgcatca tcttcatcgt catcatcatc acgctggtgg tcctcttgct
781 gaagtaccgg aggagacaca ggaagcactc gccgcagcac acgaccacgc tgtcgctcag
841 cacactggcc acacccaagc gcagcggcaa caacaacggc tcagagccca gtgacattat
901 catcccgcta aggactgcgg acagcgtctt ctgccctcac tacgagaagg tcagcgggga
961 ctacgggcac ccggtgtaca tcgtccagga gatgcccccg cagagcccgg cgaacattta
1021 ctacaaggtc tgagagggac cctggtggta cctgtgcttt cccagaggac acctaatgtc
1081 ccgatgcctc ccttgagggt ttgagagccc gcgtgctgga gaattgactg aagcacagca
1141 ccgggggaga gggacactcc tcctcggaag agcccgtcgc gctggacagc ttacctagtc
1201 ttgtagcatt cggccttggt gaacacacac gctccctgga agctggaaga ctgtgcagaa
1261 gacgcccatt cggactgctg tgccgcgtcc cacgtctcct cctcgaagcc atgtgctgcg
1321 gtcactcagg cctctgcaga agccaaggga agacagtggt ttgtggacga gagggctgtg
1381 agcatcctgg caggtgcccc aggatgccac gcctggaagg gccggcttct gcctggggtg
1441 catttccccc gcagtgcata ccggacttgt cacacggacc tcgggctagt taaggtgtgc
1501 aaagatctct agagtttagt ccttactgtc tcactcgttc tgttacccag ggctctgcag
1561 cacctcacct gagacctcca ctccacatct gcatcactca tggaacactc atgtctggag
1621 tcccctcctc cagccgctgg caacaacagc ttcagtccat gggtaatccg ttcatagaaa
1681 ttgtgtttgc taacaaggtg ccctttagcc agatgctagg ctgtctgcga agaaggctag
1741 gagttcatag aagggagtgg ggctggggaa agggctggct gcaattgcag ctcactgctg
1801 ctgcctctga aacagaaagt tggaaaggaa aaaagaaaaa agcaattagg tagcacagca
1861 ctttggtttt gctgagatcg aagaggccag taggagacac gacagcacac acagtggatt
1921 ccagtgcatg gggaggcggt cgacgagctc gag
//