LOCUS HUMFRIZ 1923 bp mRNA linear HUM 24-MAY-1996
DEFINITION Human frizzled gene product mRNA, complete cds.
ACCESSION L37882
VERSION L37882.1
KEYWORDS frizzled gene; polarity gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1923)
AUTHORS Zhao,Z., Lee,C.C., Baldini,A. and Caskey,C.T.
TITLE A human homologue of the Drosophila polarity gene frizzled has been
identified and mapped to 17q21.1
JOURNAL Genomics 27 (2), 370-373 (1995)
PUBMED 7558010
FEATURES Location/Qualifiers
source 1..1923
/db_xref="H-InvDB:HIT000193353"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.1"
/tissue_type="ovary"
/clone_lib="fz-2"
gene 1..1923
/gene="frizzled"
CDS 133..1830
/gene="frizzled"
/function="development"
/note="polarity gene; putative"
/codon_start=1
/protein_id="AAB46397.1"
/translation="MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISI
PLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTV
LEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGA
PALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGE
RDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYP
ERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMML
YFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQ
IDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGT
KTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPA
HYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV"
BASE COUNT 306 a 671 c 590 g 356 t
ORIGIN
1 cgagtaaagt ttgcaaagag gcgcgggagg cggcagccgc agcgaggagg cggcggggaa
61 gaagcgcagt ctccgggttg ggggcggggg cggggggggc gccaaggagc cgggtggggg
121 gcggcggcca gcatgcggcc ccgcagcgcc ctgccccgcc tgctgctgcc gctgctgctg
181 ctgcccgccg ccgggccggc ccagttccac ggggagaagg gcatctccat cccggaccac
241 ggcttctgcc agcccatctc catcccgctg tgcacggaca tcgcctacaa ccagaccatc
301 atgcccaacc ttctgggcca cacgaaccag gaggacgcag gcctagaggt gcaccagttc
361 tatccgctgg tgaaggtgca gtgctcgccc gaactgcgct tcttcctgtg ctccatgtac
421 gcacccgtgt gcaccgtgct ggaacaggcc atcccgccgt gccgctctat ctgtgagcgc
481 gcgcgccagg gctgcgaagc cctcatgaac aagttcggtt ttcagtggcc cgagcgcctg
541 cgctgcgagc acttcccgcg ccacggcgcc gagcagatct gcgtcggcca gaaccactcc
601 gaggacggag ctcccgcgct actcaccacc gcgccgccgc cgggactgca gccgggtgcc
661 gggggcaccc cgggtggccc gggcggcggc ggcgctcccc cgcgctacgc cacgctggag
721 caccccttcc actgcccgcg cgtcctcaag gtgccatcct atctcagcta caagtttctg
781 ggcgagcgtg attgtgctgc gccctgcgaa cctgcgcggc ccgatggttc catgttcttc
841 tcacaggagg agacgcgttt cgcgcgcctc tggatcctca cctggtcggt gctgtgctgc
901 gcttccacct tcttcactgt caccacgtac ttggtagaca tgcagcgctt ccgctaccca
961 gagcggccta tcatttttct gtcgggctgc tacaccatgg tgtcggtggc ctacatcgcg
1021 ggcttcgtgc tccaggagcg cgtggtgtgc aacgagcgct tctccgagga cggttaccgc
1081 acggtggtgc agggcaccaa gaaggagggc tgcaccatcc tcttcatgat gctctacttc
1141 ttcagcatgg ccagctccat ctggtgggtc atcctgtcgc tcacctggtt cctggcagcc
1201 ggcatgaagt ggggccacga ggccatcgag gccaactctc agtacttcca cctggccgcc
1261 tgggccgtgc cggccgtcaa gaccatcacc atcctggcca tgggccagat cgacggcgac
1321 ctgctgagcg gcgtgtgctt cgtaggcctc aacagcctgg acccgctgcg gggcttcgtg
1381 ctagcgccgc tcttcgtgta cctgttcatc ggcacgtcct tcctcctggc cggcttcgtg
1441 tcgctcttcc gcatccgcac catcatgaag cacgacggca ccaagaccga aaagctggag
1501 cggctcatgg tgcgcatcgg cgtcttctcc gtgctctaca cagtgcccgc caccatcgtc
1561 atcgcttgct acttctacga gcaggccttc cgcgagcact gggagcgctc gtgggtgagc
1621 cagcactgca agagcctggc catcccgtgc ccggcgcact acacgccgcg catgtcgccc
1681 gacttcacgg tctacatgat caaatacctc atgacgctca tcgtgggcat cacgtcgggc
1741 ttctggatct ggtcgggcaa gacgctgcac tcgtggagga agttctacac tcgcctcacc
1801 aacagccgac acggtgagac caccgtgtga gggacgcccc caggccggaa ccgcgcggcg
1861 ctttcctccg cccggggtgg ggcccctaca gactccgtat tttatttttt taaataaaaa
1921 agc
//