LOCUS HUMMKK3A 2030 bp mRNA linear HUM 28-FEB-1995
DEFINITION Homo sapiens MAP kinase kinase 3 (MKK3) mRNA, complete cds.
ACCESSION L36719
VERSION L36719.1
KEYWORDS MAP kinase kinase; mitogen activated protein kinase; protein
kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2030)
AUTHORS Derijard,B., Raingeaud,J., Barrett,T., Wu,I.H., Han,J.,
Ulevitch,R.J. and Davis,R.J.
TITLE Independent human MAP-kinase signal transduction pathways defined
by MEK and MKK isoforms
JOURNAL Science 267 (5198), 682-685 (1995)
PUBMED 7839144
COMMENT Original source text: Homo sapiens brain cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2030
/db_xref="H-InvDB:HIT000193270"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/note="vector lamda ZAPII"
gene 1..2030
/gene="MKK3"
mRNA 1..2030
/gene="MKK3"
5'UTR 1..337
/gene="MKK3"
CDS 338..1294
/gene="MKK3"
/function="protein kinase"
/codon_start=1
/product="MAP kinase kinase 3"
/protein_id="AAC41718.1"
/translation="MSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRG
AYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALF
REGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHR
DVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNV
KSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQC
LRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKKILGEDS"
3'UTR 1292..2030
/gene="MKK3"
BASE COUNT 415 a 610 c 576 g 429 t
ORIGIN
1 tggctggcaa tggccttgct gacctcgagc cgggcccacg tggggacctt tggagcacag
61 cctacgatcc tggtgcaagg ccggtggatg cagaggccag tccatatacc acccaggcct
121 gcgaggagcg tggtccccac ccatccagcc catatgtgca agtgcccttg acagagaggc
181 tggtcatatc catggtgacc atttatgggc cacaacaggt ccccatctgc gcagtgaacc
241 ctgtgctgag caccttgcag acgtgatctt gcttcgtcct gcagcactgt gcggggcagg
301 aaaatccaag aggaagaagg atctacggat atcctgcatg tccaagccac ccgcacccaa
361 ccccacaccc ccccggaacc tggactcccg gaccttcatc accattggag acagaaactt
421 tgaggtggag gctgatgact tggtgaccat ctcagaactg ggccgtggag cctatggggt
481 ggtagagaag gtgcggcacg cccagagcgg caccatcatg gccgtgaagc ggatccgggc
541 caccgtgaac tcacaggagc agaagcggct gctcatggac ctggacatca acatgcgcac
601 ggtcgactgt ttctacactg tcaccttcta cggggcacta ttcagagagg gagacgtgtg
661 gatctgcatg gagctcatgg acacatcctt ggacaagttc taccggaagg tgctggataa
721 aaacatgaca attccagagg acatccttgg ggagattgct gtgtctatcg tgcgggccct
781 ggagcatctg cacagcaagc tgtcggtgat ccacagagat gtgaagccct ccaatgtcct
841 tatcaacaag gagggccatg tgaagatgtg tgactttggc atcagtggct acttggtgga
901 ctctgtggcc aagacgatgg atgccggctg caagccctac atggcccctg agaggatcaa
961 cccagagctg aaccagaagg gctacaatgt caagtccgac gtctggagcc tgggcatcac
1021 catgattgag atggccatcc tgcggttccc ttacgagtcc tgggggaccc cgttccagca
1081 gctgaagcag gtggtggagg agccgtcccc ccagctccca gccgaccgtt tctcccccga
1141 gtttgtggac ttcactgctc agtgcctgag gaagaacccc gcagagcgta tgagctacct
1201 ggagctgatg gagcacccct tcttcacctt gcacaaaacc aagaagacgg acattgctgc
1261 cttcgtgaag aagatcctgg gagaagactc ataggggctg ggcctcggac cccactccgg
1321 ccctccagag ccccacagcc ccatctgcgg gggcagtgct cacccacacc ataagctact
1381 gccatcctgg cccagggcat ctgggaggaa ccgagggggc tgctcccacc tggctctgtg
1441 gcgagccatt tgtcccaagt gccaaagaag cagaccattg gggctcccag ccaggccctt
1501 gtcggcccca ccagtgcctc tccctgctgc tcctaggacc cgtctccagc tgctgagatc
1561 ctggactgag ggggcctgga tgccccctgt ggatgctgct gcccctgcac agcaggctgc
1621 cagtgcctgg gtggatgggc caccgccttg cccagcctgg atgccatcca agttgtatat
1681 ttttttaatc tctcgactga atggactttg cacactttgg cccagggtgg ccacacctct
1741 atcccggctt tggtgcgggg tacacaagag gggatgagtt gtgtgaatac cccaagactc
1801 ccatgaggga gatgccatga gccgcccaag gccttcccct ggcactggca aacagggcct
1861 ctgcggagca cactggctca cccagtcctg cccgccaccg ttatcggtgt cattcacctt
1921 tcgtgttttt tttaatttat cctctgttga ttttttcttt tgctttatgg gtttggcttg
1981 tttttcttgc atggtttgga gctgatcgct tctcccccac cccctagggg
//