LOCUS HUMHVRP 1640 bp mRNA linear HUM 16-FEB-1995
DEFINITION Human helodermin-preferring VIP receptor (VIP2/PACAP receptor)
mRNA, complete cds.
ACCESSION L36566
VERSION L36566.1
KEYWORDS PACAP receptor; VIP receptor; helodermin-preferring VIP receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1640)
AUTHORS Svoboda,M., Tastenoy,M., Van Rampelbergh,J., Goossens,J.F., De
Neef,P., Waelbroeck,M. and Robberecht,P.
TITLE Molecular cloning and functional characterization of a human VIP
receptor from SUP-T1 lymphoblasts
JOURNAL Biochem. Biophys. Res. Commun. 205 (3), 1617-1624 (1994)
PUBMED 7811244
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1640
/db_xref="H-InvDB:HIT000193259"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="SUP T1 lymphoblast"
/clone_lib="lamda ZAP II"
CDS 163..1479
/function="VIP and PACAP receptor"
/note="human VIP2 receptor was previously called
'helodermin-preferring VIP receptor'; transmembrane
domains are located at positions: 637-696; 772-844;
880-948; 1003-1071; 1147-1209; 1243-1302.; Potential
glycosylation sites are located at :334-336; 424-426;
436-438."
/codon_start=1
/protein_id="AAC37569.1"
/translation="MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCTELLRS
QTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETF
PDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNY
IHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFF
WLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTND
HSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLI
PLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRS
RCPTPSASRDYRVCGSSFSHNGSEGALQFHRASRAQSFLQTETSVI"
sig_peptide 163..231
/note="putative; putative"
mat_peptide 232..1476
/product="unnamed"
/function="VIP and PACAP receptor"
BASE COUNT 315 a 512 c 461 g 352 t
ORIGIN
1 cgggacgagg gggcggcccc cgcgctcggg gcgctcggct acagctgcgg ggcccgaggt
61 ctccgcgcac tcgctcccgg cccatgctgg aggcggcgga acccggggga cctaggacgg
121 aggcggcggg cgctgggcgg cccccggcac gctgagctcg ggatgcggac gctgctgcct
181 cccgcgctgc tgacctgctg gctgctcgcc cccgtgaaca gcattcaccc agaatgccga
241 tttcatctgg aaatacagga ggaagaaaca aaatgtacag agcttctgag gtctcaaaca
301 gaaaaacaca aagcctgcag tggcgtctgg gacaacatca cgtgctggcg gcctgccaat
361 gtgggagaga ccgtcacggt gccctgccca aaagtcttca gcaattttta cagcaaagca
421 ggaaacataa gcaaaaactg tacgagtgac ggatggtcag agacgttccc agatttcgtc
481 gatgcctgtg gctacagcga cccggaggat gagagcaaga tcacgtttta tattctggtg
541 aaggccattt ataccctggg ctacagtgtc tctctgatgt ctcttgcaac aggaagcata
601 attctgtgcc tcttcaggaa gctgcactgc accaggaatt acatccacct gaacctgttc
661 ctgtccttca tcctgagagc catctcagtg ctggtcaagg acgacgttct ctactccagc
721 tctggcacgt tgcactgccc tgaccagcca tcctcctggg tgggctgcaa gctgagcctg
781 gtcttcctgc agtactgcat catggccaac ttcttctggc tgctggtgga ggggctctac
841 ctccacaccc tcctggtggc catgctcccc cctagaaggt gcttcctggc ctacctcctg
901 atcggatggg gcctccccac cgtctgcatc ggtgcatgga ctgcggccag gctctactta
961 gaagacaccg gttgctggga tacaaacgac cacagtgtgc cctggtgggt catacgaata
1021 ccgattttaa tttccatcat cgtcaatttt gtccttttca ttagtattat acgaattttg
1081 ctgcagaagt taacatcccc agatgtcggc ggcaacgacc agtctcagta caagaggctg
1141 gccaagtcca cgctcctgct tatcccgctg ttcggcgtcc actacatggt gtttgccgtg
1201 tttcccatca gcatctcctc caaataccag atactgtttg agctgtgcct cgggtcgttc
1261 cagggcctgg tggtggccgt cctctactgt ttcctgaaca gtgaggtgca gtgcgagctg
1321 aagcgaaaat ggcgaagccg gtgcccgacc ccgtccgcga gccgggatta cagggtctgc
1381 ggttcctcct tctcccacaa cggctcggag ggcgccctgc agttccaccg cgcgtcccga
1441 gcccagtcct tcctgcaaac ggagacctcg gtcatctagc cccacccctg cctgtcggac
1501 gcggcgggag gcccacggtt cggggcttct gcggggctga gacgccggct tcctccttcc
1561 agatgcccga gcaccgtgtc gggcaggtca gcgcggtcct gactccgtca agctggttgt
1621 ccactaaacc ccatacctgg
//