LOCUS HUMGCSL 1610 bp mRNA linear HUM 14-APR-1995
DEFINITION Homo sapiens gamma-glutamylcysteine synthetase light subunit mRNA,
complete cds.
ACCESSION L35546
VERSION L35546.1
KEYWORDS gamma-glutamylcysteine synthetase; gamma-glutamylcysteine
synthetase light subunit.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1610)
AUTHORS Gipp,J.J., Bailey,H.H. and Mulcahy,R.T.
TITLE Cloning and sequencing of the cDNA for the light subunit of human
liver gamma-glutamylcysteine synthetase and relative mRNA levels
for heavy and light subunits in human normal tissues
JOURNAL Biochem. Biophys. Res. Commun. 206 (2), 584-589 (1995)
PUBMED 7826375
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1610
/db_xref="H-InvDB:HIT000193232"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="male"
/tissue_type="liver"
mRNA 1..1610
5'UTR 1..253
CDS 254..1078
/codon_start=1
/product="gamma-glutamylcysteine synthetase light subunit"
/protein_id="AAA65028.1"
/translation="MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELH
DCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNS
SSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIV
AIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPK
ELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS"
3'UTR 1079..1610
regulatory 1588..1593
/regulatory_class="polyA_signal_sequence"
polyA_site 1610
BASE COUNT 435 a 378 c 355 g 442 t
ORIGIN
1 ggcacgaggc tgcggccgca gtagccggag ccggagccgc agccaccggt gccttccttt
61 cccgccgccg cccagccgcc gtccggcctc cctcgggccc gagcgcagac caggctccag
121 ccgcgcggcg ccggcagcct cgcgctccct ctcgggtctc tctcgggcct cgggcaccgc
181 gtcctgtggg cggccgcctg cctgcccgcc cgcccgcagc cccttgcctg ccggcccctg
241 ggcggcccgt gccatgggca ccgacagccg cgcggccaag gcgctcctgg cgcgggcccg
301 caccctgcac ctgcagacgg ggaacctgct gaactggggc cgcctgcgga agaagtgccc
361 gtccacgcac agcgaggagc ttcatgattg tatccaaaaa accttgaatg aatggagttc
421 ccaaatcaac ccagatttgg tcagggagtt tccagatgtc ttggaatgca ctgtatctca
481 tgcagtagaa aagataaatc ctgatgaaag agaagaaatg aaagtttctg caaaactgtt
541 cattgtagaa tcaaactctt catcatcaac tagaagtgca gttgacatgg cctgttcagt
601 ccttggagtt gcacagctgg attctgtgat cattgcttca cctcctattg aagatggagt
661 taatctttcc ttggagcatt tacagcctta ctgggaggaa ttagaaaact tagttcagag
721 caaaaagatt gttgccatag gtacctctga tctagacaaa acacagttgg aacagctgta
781 tcagtgggca caggtaaaac caaatagtaa ccaagttaat cttgcctcct gctgtgtgat
841 gccaccagat ttgactgcat ttgctaaaca atttgacata cagctgttga ctcacaatga
901 tccaaaagaa ctgctttctg aagcaagttt ccaagaagct cttcaggaaa gcattcctga
961 cattcaagcg cacgagtggg tgccgctgtg gctactgcgg tattcggtca ttgtgaaaag
1021 tagaggaatt atcaaatcaa aaggctacat tttacaagct aaaagaaggg gttcttaact
1081 gacttaggag cataacttac ctgtaatttc cttcaatatg agagaaaatt gagatgtgta
1141 aaatctagtt actgcctgta aatggtgtca ttgaggcaga tattctttcg tcatatttga
1201 cagtatgttg tctgtcaagt tttaaatact tatcttgcct ccatatcaat ccattctcat
1261 gaacctctgt attgctttcc ttaaactatt gttttctaat tgaaattgtc tataaagaaa
1321 atacttgcaa tatatttttc ctttattttt atgactaata taaatcaaga aaatttgttg
1381 ttagatatat tttggcctag gtatcagggt aatgtatata catatttttt atttccaaaa
1441 aaaattcatt aattgcttct taactcttat tataaccaag caatttaatt acaattgtta
1501 aaactgaaat actggaagaa gatatttttc ctgtcattga tgagatatat cagagtaact
1561 ggagtagctg ggatttacta gtagtgtaaa taaaattcac tcttcaatac
//