LOCUS HUMECPC 1284 bp mRNA linear HUM 13-MAR-1995
DEFINITION Homo sapiens endothelial cell protein C/APC receptor (EPCR) mRNA,
complete cds.
ACCESSION L35545
VERSION L35545.1
KEYWORDS endothelial cell protein C/APC receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1284)
AUTHORS Fukudome,K. and Esmon,C.T.
TITLE Identification, cloning, and regulation of a novel endothelial cell
protein C/activated protein C receptor
JOURNAL J. Biol. Chem. 269 (42), 26486-26491 (1994)
PUBMED 7929370
COMMENT Original source text: Homo sapiens endothelial cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1284
/db_xref="H-InvDB:HIT000193231"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="endothelial"
gene 1..1284
/gene="EPCR"
mRNA 1..1284
/gene="EPCR"
CDS 25..741
/gene="EPCR"
/note="amino acid feature: transmembrane domain, bp 655 ..
729"
/codon_start=1
/product="endothelial cell protein C/APC receptor"
/protein_id="AAA63647.1"
/translation="MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWY
QGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQ
ERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGV
VTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVG
GFIIAGVAVGIFLCTGGRRC"
sig_peptide 25..69
/gene="EPCR"
/note="putative"
mat_peptide 70..738
/gene="EPCR"
/product="endothelial cell protein C/APC receptor"
polyA_site 1275
/gene="EPCR"
BASE COUNT 322 a 325 c 341 g 296 t
ORIGIN
1 caggtccgga gcctcaactt caggatgttg acaacattgc tgccgatact gctgctgtct
61 ggctgggcct tttgtagcca agacgcctca gatggcctcc aaagacttca tatgctccag
121 atctcctact tccgcgaccc ctatcacgtg tggtaccagg gcaacgcgtc gctgggggga
181 cacctaacgc acgtgctgga aggcccagac accaacacca cgatcattca gctgcagccc
241 ttgcaggagc ccgagagctg ggcgcgcacg cagagtggcc tgcagtccta cctgctccag
301 ttccacggcc tcgtgcgcct ggtgcaccag gagcggacct tggcctttcc tctgaccatc
361 cgctgcttcc tgggctgtga gctgcctccc gagggctcta gagcccatgt cttcttcgaa
421 gtggctgtga atgggagctc ctttgtgagt ttccggccgg agagagcctt gtggcaggca
481 gacacccagg tcacctccgg agtggtcacc ttcaccctgc agcagctcaa tgcctacaac
541 cgcactcggt atgaactgcg ggaattcctg gaggacacct gtgtgcagta tgtgcagaaa
601 catatttccg cggaaaacac gaaagggagc caaacaagcc gctcctacac ttcgctggtc
661 ctgggcgtcc tggtgggcgg tttcatcatt gctggtgtgg ctgtaggcat cttcctgtgc
721 acaggtggac ggcgatgtta attactctcc agccccgtca gaaggggctg gattgatgga
781 ggctggcaag ggaaagtttc agctcactgt gaagccagac tccccaactg aaacaccaga
841 aggtttggag tgacagctcc tttcttctcc cacatctgcc cactgaagat ttgagggagg
901 ggagatggag aggagaggtg gacaaagtac ttggtttgct aagaacctaa gaacgtgtat
961 gctttgctga attagtctga taagtgaatg tttatctatc tttgtggaaa acagataatg
1021 gagttggggc aggaagccta tgcgccatcc tccaaagaca gacagaatca cctgaggcgt
1081 tcaaaagata taaccaaata aacaagtcat ccacaatcaa aatacaacat tcaatacttc
1141 caggtgtgtc agacttggga tgggacgctg atataatagg gtagaaagaa gtaacacgaa
1201 gaagtggtgg aaatgtaaaa tccaagtcat atggcagtga tcaattatta atcaattaat
1261 aatattaata aatttcttat attt
//