LOCUS HUMCSBP1 3757 bp mRNA linear HUM 22-DEC-1994
DEFINITION Human CSaids binding protein (CSBP1) mRNA, complete cds.
ACCESSION L35263
VERSION L35263.1
KEYWORDS CSaids binding protein; protein kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3757)
AUTHORS Lee,J.C., Laydon,J.T., McDonnell,P.C., Gallagher,T.F., Kumar,S.,
Green,D.W., McNulty,D., Blumenthal,M.J., Heys,R.J.,
Landvatter,S.W., Strickler,J.E., McLaughlin,M.M., Siemens,I.,
Fisher,S.H., Livi,G.P., White,J.R., Adams,J.L. and Young,P.R.
TITLE A protein kinase involved in the regulation of inflammatory
cytokine biosynthesis
JOURNAL Nature 372 (6508), 739-746 (1994)
PUBMED 7997261
COMMENT Original source text: Homo sapiens (tissue library: lambda ZAP)
peripheral blood cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3757
/db_xref="H-InvDB:HIT000193222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="GM-CSF stimulated monocyte"
/tissue_type="peripheral blood"
/tissue_lib="lambda ZAP"
gene 1..3757
/gene="CSBP1"
mRNA 1..3757
/gene="CSBP1"
5'UTR 1..362
/gene="CSBP1"
CDS 363..1445
/gene="CSBP1"
/function="regulation of inflammatory cytokine
biosynthesis"
/codon_start=1
/product="CSaids binding protein"
/protein_id="AAA57455.1"
/translation="MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDT
KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDV
YLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE
DCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLT
GRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIG
ANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLI
DEWKSLTYDEVISFVPPPLDQEEMES"
3'UTR 1446..3757
/gene="CSBP1"
regulatory 2854..2859
/regulatory_class="polyA_signal_sequence"
/gene="CSBP1"
polyA_site 2874
/gene="CSBP1"
regulatory 3735..3740
/regulatory_class="polyA_signal_sequence"
/gene="CSBP1"
polyA_site 3757
/gene="CSBP1"
BASE COUNT 947 a 832 c 945 g 1033 t
ORIGIN
1 ggaaccgcga ccactggagc cttagcgggc gcagcagctg gaacgggagt actgcgacgc
61 agcccggagt cggccttgta ggggcgaagg tgcagggaga tcgcggcggg cgcagtcttg
121 agcgccggag cgcgtccctg cccttagcgg ggcttgcccc agtcgcaggg gcacatccag
181 ccgctgcggc tgacagcagc cgcgcgcgcg ggagtctgcg gggtcgcggc agccgcacct
241 gcgcgggcga ccagcgcaag gtccccgccc ggctgggcgg gcagcaaggg ccggggagag
301 ggtgcgggtg caggcggggg ccccacaggg ccaccttctt gcccggcggc tgccgctgga
361 aaatgtctca ggagaggccc acgttctacc ggcaggagct gaacaagaca atctgggagg
421 tgcccgagcg ttaccagaac ctgtctccag tgggctctgg cgcctatggc tctgtgtgtg
481 ctgcttttga cacaaaaacg gggttacgtg tggcagtgaa gaagctctcc agaccatttc
541 agtccatcat tcatgcgaaa agaacctaca gagaactgcg gttacttaaa catatgaaac
601 atgaaaatgt gattggtctg ttggacgttt ttacacctgc aaggtctctg gaggaattca
661 atgatgtgta tctggtgacc catctcatgg gggcagatct gaacaacatt gtgaaatgtc
721 agaagcttac agatgaccat gttcagttcc ttatctacca aattctccga ggtctaaagt
781 atatacattc agctgacata attcacaggg acctaaaacc tagtaatcta gctgtgaatg
841 aagactgtga gctgaagatt ctggattttg gactggctcg gcacacagat gatgaaatga
901 caggctacgt ggccactagg tggtacaggg ctcctgagat catgctgaac tggatgcatt
961 acaaccagac agttgatatt tggtcagtgg gatgcataat ggccgagctg ttgactggaa
1021 gaacattgtt tcctggtaca gaccatatta accagcttca gcagattatg cgtctgacag
1081 gaacaccccc cgcttatctc attaacagga tgccaagcca tgaggcaaga aactatattc
1141 agtctttgac tcagatgccg aagatgaact ttgcgaatgt atttattggt gccaatcccc
1201 tggctgtcga cttgctggag aagatgcttg tattggactc agataagaga attacagcgg
1261 cccaagccct tgcacatgcc tactttgctc agtaccacga tcctgatgat gaaccagtgg
1321 ccgatcctta tgatcagtcc tttgaaagca gggacctcct tatagatgag tggaaaagcc
1381 tgacctatga tgaagtcatc agctttgtgc caccacccct tgaccaagaa gagatggagt
1441 cctgagcacc tggtttctgt tctgttgatc ccacttcact gtgaggggaa ggccttttca
1501 cgggaactct ccaaatatta ttcaagtgcc tcttgttgca gagatttcct ccatggtgga
1561 agggggtgtg cgtgcgtgtg cgtgcgtgtt agtgtgtgtg catgtgtgtg tctgtctttg
1621 tgggagggta agacaatatg aacaaactat gatcacagtg actttacagg aggttgtgga
1681 tgctccaggg cagcctccac cttgctcttc tttctgagag ttggctcagg cagacaagag
1741 ctgctgtcct tttaggaata tgttcaatgc aaagtaaaaa aatatgaatt gtccccaatc
1801 ccggtcatgc ttttgccact ttggcttctc ctgtgacccc accttgacgg tggggcgtag
1861 acttgacaac atcccacagt ggcacggaga gaaggcccat accttctggt tgcttcagac
1921 ctgacaccgt ccctcagtga tacgtacagc caaaaaggac caactggctt ctgtgcacta
1981 gcctgtgatt aacttgctta gtatggttct cagatcttga cagtatattt gaaactgtaa
2041 atatgtttgt gccttaaaag gagagaagaa agtgtagata gttaaaagac tgcagctgct
2101 gaagttctga gccgggcaag tcgagagggc tgttggacag ctgcttgtgg gcccggagta
2161 atcaggcagc cttcataggc ggtcatgtgt gcatgtgagc acatgcgtat atgtgcgtct
2221 ctctttctcc ctcaccccca ggtgttgcca tttctctgct tacccttcac ctttggtgca
2281 gaggtttctt gaatatctgc cccagtagtc agaagcaggt tcttgatgtc atgtacttcc
2341 tgtgtactct ttatttctag cagagtgagg atgtgttttg cacgtcttgc tatttgagca
2401 tgcacagctg cttgtcctgc tctcttcagg aggccctggt gtcaggcagg tttgccagtg
2461 aagacttctt gggtagttta gatcccatgt cacctcagct gatattatgg caagtgatat
2521 cacctctctt cagcccctag tgctattctg tgttgaacac aattgatact tcaggtgctt
2581 ttgatgtgaa aatcatgaaa agaggaacag gtggatgtat agcattttta ttcatgccat
2641 ctgttttcaa ccaactattt ttgaggaatt atcatgggaa aagaccaggg cttttcccag
2701 gaatatccca aacttcggaa acaagttatt ctcttcactc ccaataacta atgctaagaa
2761 atgctgaaaa tcaaagtaaa aaattaaagc ccataaggcc agaaactcct tttgctgtct
2821 ttctctaaat atgattactt taaaataaaa aagtaacaag gtgtcttttc cactcctatg
2881 gaaaagggtc ttcttggcag cttaacattg acttcttggt ttggggagaa ataaattttg
2941 tttcagaatt ttgtatattg taggaatccc tttgagaatg tgattccttt tgatggggag
3001 aaagggcaaa ttattttaat attttgtatt ttcaacttta taaagataaa atatcctcag
3061 gggtggagaa gtgtcgtttt cataacttgc tgaatttcag gcattttgtt ctacatgagg
3121 actcatatat ttaagccttt tgtgtaataa gaaagtataa agtcacttcc agtgttggct
3181 gtgtgacaga atcttgtatt tgggccaagg tgtttccatt tctcaatcag tgcagtgata
3241 catgtactcc agagggacag ggtggacccc ctgagtcaac tggagcaaga aggaaggagg
3301 cagactgatg gcgattccct ctcacccggg actctccccc tttcaaggaa agtgaacctt
3361 taaagtaaag gcctcatctc ctttattgca gttcaaatcc tcaccatcca cagcaagatg
3421 aattttatca gccatgtttg gttgtaaatg ctcgtgtgat ttcctacaga aatactgctc
3481 tgaatatttt gtaataaagg tctttgcaca tgtgaccaca tacgtgttag gaggctgcat
3541 gctctggaag cctggactct aagctggagc tcttggaaga gctcttcggt ttctgagcat
3601 aatgctccca tctcctgatt tctctgaaca gaaaacaaaa gagagaatga gggaaattgc
3661 tattttattt gtattcatga acttggctgt aatcagttat gccgtatagg atgtcagaca
3721 ataccactgg ttaaaataaa gcctattttt caaattt
//