LOCUS HUMMTINFB 2481 bp mRNA linear HUM 22-MAY-1995
DEFINITION Human nuclear-encoded mitochondrial initiation factor 2 mRNA,
complete cds.
ACCESSION L34600
VERSION L34600.1
KEYWORDS initiation factor; initiation factor 2; mitochondrial protein;
protein synthesis.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2481)
AUTHORS Ma,L. and Spremulli,L.L.
TITLE Cloning and sequence analysis of the human mitochondrial
translational initiation factor 2 cDNA
JOURNAL J. Biol. Chem. 270 (4), 1859-1865 (1995)
PUBMED 7829522
COMMENT Original source text: Homo sapiens liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2481
/db_xref="H-InvDB:HIT000193166"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
CDS 271..2454
/note="initiation factor 2 for mitochondrial protein
synthesis"
/codon_start=1
/product="initiation factor 2"
/protein_id="AAA67038.1"
/translation="MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVW
TAQLCAWPWPTDVLNGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEEL
ARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVR
KNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIG
AFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHA
KDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMAL
AEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKC
WAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYE
QEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEK
RERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDISANDVNLAET
FDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVG
EASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDD
ISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGF"
BASE COUNT 836 a 419 c 605 g 621 t
ORIGIN
1 ggcacgagca gaatccaggg gcccggggct gtagattcct tgacaaggat atcctagcgg
61 cgaaacaaca ccgtactggg agtcagaacg tctgggttct agtcttgact gccattaact
121 agcggtatga cattggagaa gcttttttga cccttctgga tttccgtttc cttttctgta
181 aaatgaggag cttggaagat ccggaaaatg aggcccatag gaaacaagtg acttgctgag
241 tccagataac actgactgtc agagagaaac atgaaccaga agctactgaa gttggagaac
301 ttgctacgat ttcacactat ttataggcaa ctgcacagtc tgtgtcaaag aagagcatta
361 agacagtgga ggcatgggtt ttcatctgct taccctgtgt ggacagctca actgtgtgcc
421 tggccctggc caacagatgt gctcaatggg gctgctttat ctcagtatag gcttctagta
481 acaaaaaagg aagaaggacc atggaaatct cagttatctt caacaaaatc taaaaaggtg
541 gtagaagtat ggattggaat gactattgag gaactggcca gggcaatgga aaaaaacaca
601 gattatgtat atgaagcttt attgaacact gatattgaca tagattcact ggaagcagac
661 tcacatttag atgaagtctg gatcaaagaa gtgataacga aggcagggat gaagttaaag
721 tggagtaaat taaaacagga caaagtcaga aaaaataaag atgctgtaag aaggccccag
781 gcagatccag ctttattaac cccaaggtcc ccagttgtta ctataatggg ccatgttgat
841 cacgggaaaa cgacattact tgacaaattt cgaaaaactc aagtggcagc agtggaaact
901 ggaggcatca ctcagcacat tggtgccttt cttgtctctc tgccttctgg ggaaaagata
961 acttttcttg atactccagg acatgctgct ttctcagcaa tgagagccag aggtgctcag
1021 gtcactgaca ttgtcgtatt ggttgtagct gcagatgatg gagtgatgaa acaaactgta
1081 gaatctattc agcatgccaa agatgcacag gttcctatta tccttgccgt aaataaatgt
1141 gacaaagctg aggctgatcc tgagaaagtg aaaaaagagc tgctggctta cgatgtggta
1201 tgtgaagatt atggaggtga tgttcaagca gtgcctgtct ccgcacttac gggcgataat
1261 ctgatggctt tggcagaagc aacagttgct cttgcagaaa tgttagaatt gaaagcagat
1321 cccaatggtc cagtggaagg aacagtaata gagtctttca cagacaaagg aagaggtctt
1381 gttactacag ctataattca aagaggaact ttaagaaaag gctctgttct ggttgctgga
1441 aaatgttggg caaaagtacg cttaatgttt gatgaaaatg gaaaaacaat tgatgaggcc
1501 tatcccagca tgccagtggg aattacaggc tggagagacc ttccttctgc aggagaagaa
1561 attcttgaag tagaatctga gccaagggca cgtgaagttg ttgactggag gaaatatgaa
1621 caagaacagg agaaaggtca ggaggatctg aaaataatag aagaaaagcg aaaggaacac
1681 aaagaagcac atcagaaagc ccgtgagaag tatggccatc tactgtggaa gaagagatca
1741 attctacggt ttttagaaag aaaagaacaa atacccttaa agccaaaaga gaaaagggaa
1801 agagattcaa atgtactttc tgtgattatt aaaggtgatg ttgatggttc tgttgaggcc
1861 attttgaaca ttatagatac ctatgatgct tcacacgagt gtgaactaga attagtacat
1921 tttggagtgg gtgatataag tgcaaatgat gttaaccttg ctgaaacatt tgatggtgtt
1981 atatatggct ttaatgtgaa tgcaggcaat gttatccaac agtcagctgc aaaaaaagga
2041 gtaaaaatta aacttcacaa aataatttac cgtcttgttg aagatttgca agaggaactg
2101 agcagcagat taccctgtgc tgtggaagag cacccagtag gtgaggcatc tatactagct
2161 accttctctg taacagaagg gaagaaaaaa gttcctgtgg ctggctgcag agtccaaaag
2221 ggacagttag aaaaacaaaa aaaatttaaa ctaacccgta atggacatgt aatttggaag
2281 ggctcattaa cctcattgaa acaccataaa gatgacattt caattgtcaa aacgggaatg
2341 gattgtggtc tcagtttaga tgaagacaat atggaatttc aagtgggaga cagaattgtt
2401 tgttatgaag aaaagcaaat tcaagccaag acttcttggg atccaggatt ttaaaattac
2461 attaaaaatg taaataactc a
//