LOCUS HUMGABAT 1705 bp mRNA linear HUM 11-AUG-1995
DEFINITION Human 4-aminobutyrate aminotransferase (GABAT) mRNA, complete cds.
ACCESSION L32961
VERSION L32961.1
KEYWORDS 4-aminobutyrate aminotransferase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1705)
AUTHORS Osei,Y.D. and Churchich,J.E.
TITLE Screening and sequence determination of a cDNA encoding the human
brain 4-aminobutyrate aminotransferase
JOURNAL Gene 155 (2), 185-187 (1995)
PUBMED 7721088
COMMENT Original source text: Homo sapiens (tissue library: lambda ZAPII)
brain cortex cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1705
/db_xref="H-InvDB:HIT000193068"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain cortex"
/tissue_lib="lambda ZAPII"
gene 1..1705
/gene="GABAT"
5'UTR 1..98
/gene="GABAT"
CDS 99..1601
/gene="GABAT"
/EC_number="2.6.1.19"
/function="converts 4-aminobutyrate into succinic
semi-aldehyde"
/codon_start=1
/product="4-aminobutyrate aminotransferase"
/protein_id="AAA74449.1"
/translation="MASMLLAQRLACSFQHTYRLLVPGSRHISQAAAKVDVEFDYDGP
LMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISS
VPIGYSDPALVKLIQQPQNASMFVNRPALEILPPENFVEKLRQSLLSVAPKGMSQLIT
MACGSCSNENALKTIFMWYRSKERGQRGFSKEELETCMINQAPWCPDYSILSFMGSFH
GRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEAGCLEEVEDL
IVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHCCAFLVDEVQTGGGC
TGKFWAHEHWGLDDPADVMTFSKKMMTGGFFLKEEFRPNAPYRIFNTWLGDPSKNLLL
AEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIR
NKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK"
misc_binding 357
/gene="GABAT"
/bound_moiety="cofactor"
BASE COUNT 413 a 462 c 451 g 379 t
ORIGIN
1 ggctcactgc atctccggct cctggactca agcgattctc ctgcctcagg ctcccaaggt
61 ggcagcacgc aaagggtgtc cctgtccctc aaggggtcat ggcctccatg ttgctcgccc
121 agcggctggc ctgcagcttc cagcacacgt accgcctgct ggtgcctgga tccagacaca
181 ttagtcaagc tgcagccaaa gtcgacgttg aatttgatta tgatgggcct ctgatgaaga
241 cggaagtccc agggcctaga tctcaggagt taatgaaaca gctgaatata attcagaatg
301 cagaggctgt gcattttttc tgcaattacg aagagagccg aggcaattac ctggttgatg
361 tggacggcaa ccgaatgctg gatctttatt cccagatctc ctctgttccc ataggttaca
421 gcgacccggc cctcgtgaaa ctcatccaac agccacaaaa tgcgagcatg tttgtcaaca
481 gacccgccct cgaaatcctg cctccggaga actttgtgga gaagctccgg cagtccttgc
541 tctcggtggc tcccaaaggg atgtcccagc tcatcaccat ggcctgcggc tcctgctcca
601 atgaaaacgc cttaaagacc atcttcatgt ggtaccggag caaggaaaga gggcagaggg
661 gattctccaa agaggagctg gagacgtgca tgattaacca ggccccctgg tgccccgact
721 acagcatcct ctccttcatg ggttccttcc atgggaggac catgggttgc ttagcgacca
781 cgcactctaa agccattcac aagatcgata tcccttcctt tgactggccc atcgcaccgt
841 tcccacggct gaaataccct ctggaagagt ttgtgaaaga gaaccaacag gaagaggccg
901 gctgtctgga agaggttgag gatctgattg tgaaatatcg aaaaaagaag aagacggtgg
961 ccgggatcat cgtggagccc atccagtccg agggtggaga caaccatgca tccgatgact
1021 tctttcggaa gctgagagac atcgccagga agcactgctg cgccttcttg gtggacgagg
1081 tccagaccgg aggaggctgc acgggcaagt tctgggccca tgagcactgg ggcctggatg
1141 acccagcaga cgtgatgacc ttcagcaaga agatgatgac tgggggcttc ttcctcaagg
1201 aggagttcag gcctaatgct ccctaccgga tcttcaacac gtggctgggg gacccgtcca
1261 agaacctgtt gctggctgag gtcatcaaca tcatcaagcg ggaggacctg ctaaataatg
1321 cagcccatgc cgggaaggcc ctgctcacag gactgctgga cctccaggcc cggtaccccc
1381 agttcatcag cagggtgaga ggacgaggca ccttttgctc cttcgatact cccgatgatt
1441 ccatacggaa taagctcatt ttaattgcca gaaacaaagg tgtggtgttg ggtggctgtg
1501 gtgacaaatc cattcgtttc cgtcccacgc tggtgttcag ggatcaccac gctcacctgt
1561 tcctcaatat tttcagtgac atcttagcag acttcaagta aagaagccat ttccactaca
1621 gtgagaaagc ccggatccca acagttgtca aattgattag tttgcctaat tcatgttttc
1681 acttaaaagt atcagaggtg gaatt
//