LOCUS HUMARDE 1599 bp mRNA linear HUM 09-SEP-1994
DEFINITION Human arylacetamide deacetylase mRNA, complete cds.
ACCESSION L32179
VERSION L32179.1
KEYWORDS arylacetamide deacetylase; esterase; lipase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1599)
AUTHORS Probst,M.R., Beer,M., Beer,D., Jeno,P., Meyer,U.A. and Gasser,R.
TITLE Human liver arylacetamide deacetylase. Molecular cloning of a novel
esterase involved in the metabolic activation of arylamine
carcinogens with high sequence similarity to hormone-sensitive
lipase
JOURNAL J. Biol. Chem. 269 (34), 21650-21656 (1994)
PUBMED 8063807
COMMENT On Sep 13, 1994 this sequence version replaced gi:520826.
Original source text: Homo sapiens male adult liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1599
/db_xref="H-InvDB:HIT000192880"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="male"
/tissue_type="liver"
/dev_stage="adult"
mRNA 1..1599
5'UTR 1..85
CDS 86..1285
/codon_start=1
/product="arylacetamide deacetylase"
/protein_id="AAA35551.1"
/translation="MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQ
NLATFVELHGSSIFMDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEA
LRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDV
YNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLI
YPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSH
LFKFINWSSLLPERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPL
TYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFLGLKISHRLINQYI
EWLKENL"
3'UTR 1286..1599
polyA_site 1599
BASE COUNT 473 a 293 c 318 g 515 t
ORIGIN
1 cactgcttat taaagtacac tattcaggca tatcatgtag gtttactttc tgtgtttcta
61 gagaccaaga agcgggacgt tcaccatggg aagaaaatcg ctgtaccttc tgattgtggg
121 gatcctcata gcatattata tttatacgcc tctcccagat aacgttgagg agccatggag
181 aatgatgtgg ataaacgcac atctgaaaac tatacaaaat ttggctacat ttgtggagct
241 ccatgggagt tccattttta tggattcctt taaggttgtc gggagctttg atgaagtccc
301 accaacctca gatgaaaatg tcactgtgac tgagacaaaa ttcaacaaca ttcttgttcg
361 ggtatatgtg ccaaagagaa agtctgaagc actaagaagg gggttgtttt acatccatgg
421 tggaggctgg tgcgtgggaa gtgctgctct aagtggttat gacttgctgt caagatggac
481 agcagacaga cttgatgctg tcgtcgtatc aaccaactac agattagcac ctaagtatca
541 tttcccaatt caatttgaag atgtatataa tgccttaagg tggttcttac gtaaaaaagt
601 tcttgcaaaa tatggtgtga accctgagag aatcggtatt tctggagata gtgcaggagg
661 gaatttagct gcagcagtga ctcaacagct ccttgatgac ccagatgtca agatcaaact
721 caagatccag tctttaattt atcctgccct tcagcctctt gatgtagatt taccgtcata
781 tcaagaaaat tcaaattttc tatttctatc caaatcactc atggtcagat tctggagtga
841 atattttacc actgatagat cacttgaaaa agccatgctt tccagacaac atgtacctgt
901 ggaatcaagt catctcttca aatttattaa ttggagttcc ctgctccctg agaggtttat
961 aaaaggacat gtttataaca atccaaatta tggcagttct gagctggcta aaaaatatcc
1021 agggttccta gatgtgaggg cagccccttt gttggctgat gacaacaaat tacgtggctt
1081 acccctgacc tatgtcatca cctgtcaata tgatctctta agagatgatg gactcatgta
1141 tgtcacccga cttcgcaaca ctggggttca ggtgactcat aaccatgttg aggatggatt
1201 ccatggagca ttttcatttc tgggacttaa aattagtcac agacttataa atcagtatat
1261 tgagtggcta aaggaaaatc tatagtaaaa catgtagcta taacatattt taaaaataaa
1321 atctgaaaac ctcagaaaat ttcgattaga aattggtctt tcttagaatg gtctagttaa
1381 gttccacatg tagcataatt cttaaatagg cacttttctg tttttttttt cttactgtgg
1441 gatttcattt caattttcta cattgtctat ctgctttttc ggagattttc cttcttacac
1501 tgttaatctt attttaaaaa atattacatt cttgtatact ttatttttgt gagttggcta
1561 ctatttacga tgcaagagaa taaatgtgag caaagattg
//