LOCUS HUMA1ARA 1401 bp mRNA linear HUM 19-JUN-1995
DEFINITION Human alpha-1C-adrenergic receptor mRNA, complete cds.
ACCESSION L31774
VERSION L31774.1
KEYWORDS alpha-1C-adrenergic receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Hirasawa,A., Horie,K., Tanaka,T., Takagaki,K., Murai,M., Yano,J.
and Tsujimoto,G.
TITLE Cloning, functional expression and tissue distribution of human
cDNA for the alpha 1C-adrenergic receptor
JOURNAL Biochem. Biophys. Res. Commun. 195 (2), 902-909 (1993)
PUBMED 8396931
REFERENCE 2 (sites)
AUTHORS Tseng-Crank,J.C., Goetz,A., Saussy,D., Roberson,K.M., Hazum,S.,
Haizlip,J., Godinot,N., Wisely,B., Robertson,C.N. and Kost,T.A.
TITLE The adrenergic receptor subtypes and benign prostatic hyperplasia:
Cloning and functional expression of the human a1C receptor
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1401)
AUTHORS Schwinn,D.A., Johnston,G.I., Page,S.O., Mosley,M.J., Wilson,K.H.,
Worman,N.P., Campbell,S., Fidock,M.D., Furness,L.M.,
Parry-Smith,D.J., Peter,B. and Bailey,D.S.
TITLE Cloning and pharmacological characterization of human alpha-1
adrenergic receptors: sequence corrections and direct comparison
with other species homologues
JOURNAL J. Pharmacol. Exp. Ther. 272 (1), 134-142 (1995)
PUBMED 7815325
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1401
/db_xref="H-InvDB:HIT000192841"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..1401
/codon_start=1
/product="alpha-1C-adrenergic receptor"
/protein_id="AAB59486.1"
/translation="MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGN
ILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIW
AAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIG
PLFGWRQPAPEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGL
KSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGI
VVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFK
KAFQNVLRIQCLRRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTD
GVCEWKFFSSMPRGSARITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVP
TIKVHTISLSENGEEV"
misc_difference 127
/note="conflict"
/citation=[2]
/replace=""
misc_difference 386..387
/note="conflict"
/citation=[2]
/replace=""
misc_difference 1039
/note="conflict"
/citation=[2]
/replace=""
misc_difference 1075
/note="conflict"
/citation=[2]
/replace=""
misc_difference 1291
/note="conflict"
/citation=[1]
/replace=""
misc_difference 1324
/note="conflict"
/citation=[2]
/replace=""
BASE COUNT 288 a 442 c 360 g 311 t
ORIGIN
1 atggtgtttc tctcgggaaa tgcttccgac agctccaact gcacccaacc gccggcaccg
61 gtgaacattt ccaaggccat tctgctcggg gtgatcttgg ggggcctcat tcttttcggg
121 gtgctgggta acatcctagt gatcctctcc gtagcctgtc accgacacct gcactcagtc
181 acgcactact acatcgtcaa cctggcggtg gccgacctcc tgctcacctc cacggtgctg
241 cccttctccg ccatcttcga ggtcctaggc tactgggcct tcggcagggt cttctgcaac
301 atctgggcgg cagtggatgt gctgtgctgc accgcgtcca tcatgggcct ctgcatcatc
361 tccatcgacc gctacatcgg cgtgagctac ccgctgcgct acccaaccat cgtcacccag
421 aggaggggtc tcatggctct gctctgcgtc tgggcactct ccctggtcat atccattgga
481 cccctgttcg gctggaggca gccggccccc gaggacgaga ccatctgcca gatcaacgag
541 gagccgggct acgtgctctt ctcagcgctg ggctccttct acctgcctct ggccatcatc
601 ctggtcatgt actgccgcgt ctacgtggtg gccaagaggg agagccgggg cctcaagtct
661 ggcctcaaga ccgacaagtc ggactcggag caagtgacgc tccgcatcca tcggaaaaac
721 gccccggcag gaggcagcgg gatggccagc gccaagacca agacgcactt ctcagtgagg
781 ctcctcaagt tctcccggga gaagaaagcg gccaaaacgc tgggcatcgt ggtcggctgc
841 ttcgtcctct gctggctgcc ttttttctta gtcatgccca ttgggtcttt cttccctgat
901 ttcaagccct ctgaaacagt ttttaaaata gtattttggc tcggatatct aaacagctgc
961 atcaacccca tcatataccc atgctccagc caagagttca aaaaggcctt tcagaatgtc
1021 ttgagaatcc agtgtctccg cagaaagcag tcttccaaac atgccctggg ctacaccctg
1081 cacccgccca gccaggccgt ggaagggcaa cacaaggaca tggtgcgcat ccccgtggga
1141 tcaagagaga ccttctacag gatctccaag acggatggcg tttgtgaatg gaaatttttc
1201 tcttccatgc cccgtggatc tgccaggatt acagtgtcca aagaccaatc ctcctgtacc
1261 acagcccggg tgagaagtaa aagctttttg caggtctgct gctgtgtagg gccctcaacc
1321 cccagccttg acaagaacca tcaagttcca accattaagg tccacaccat ctccctcagt
1381 gagaacgggg aggaagtcta g
//