LOCUS HUMTYRKINA 2564 bp mRNA linear HUM 22-AUG-1995
DEFINITION Human tyrosine kinase (TXK) mRNA, complete cds.
ACCESSION L27071
VERSION L27071.1
KEYWORDS cytoplasmic protein; tyrosine kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2564)
AUTHORS Haire,R.N., Ohta,Y., Lewis,J.E., Fu,S.M., Kroisel,P. and
Litman,G.W.
TITLE TXK, a novel human tyrosine kinase expressed in T cells shares
sequence identity with Tec family kinases and maps to 4p12
JOURNAL Hum. Mol. Genet. 3 (6), 897-901 (1994)
PUBMED 7951233
REFERENCE 2 (bases 1 to 2564)
AUTHORS Litman,G.W.
TITLE Direct Submission
JOURNAL Submitted (08-JUN-1994) Gary W. Litman, All Children's Hospital,
801 6th Street South, St. Petersburg, FL 33701, USA
COMMENT On Aug 22, 1995 this sequence version replaced gi:684985.
Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2564
/db_xref="H-InvDB:HIT000192714"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4p12"
/cell_type="mononuclear"
/tissue_type="blood"
/dev_stage="adult"
gene 1..2564
/gene="TXK"
5'UTR 1..86
/gene="TXK"
CDS 87..1670
/gene="TXK"
/codon_start=1
/product="tyrosine kinase"
/protein_id="AAA74557.1"
/translation="MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQ
HRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLA
LRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQA
EHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAER
HAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKE
IGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCI
QRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLA
ARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVW
SFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPE
GRPTFAELLRAVTEIAETW"
3'UTR 1671..2564
/gene="TXK"
BASE COUNT 775 a 486 c 570 g 733 t
ORIGIN
1 gatttcagtt gaaagatgtg tttttgtgag tagagcaccg cagaagaact gaagactgtt
61 gtgtgctccc cgcagaaggg gctaccatga tcctttcctc ctataacacc atccagtcgg
121 ttttctgttg ctgctgttgc tgttcagtgc agaagcgaca aatgagaaca cagataagcc
181 tgagcacaga tgaagagctt ccagaaaaat acacccagca tcgcaggccg tggctcagcc
241 aattgtcaaa taagaagcaa tccaacacgg gccgtgtgca gccgtcaaaa cgaaagccac
301 tgcctcccct cccaccctct gaggttgctg aagagaagat ccaagtcaag gcactttatg
361 attttctgcc cagagaaccc tgtaatttag ccttaaggag agcagaagaa tacctgatac
421 tggagaaata caatcctcac tggtggaagg caagagaccg tttggggaat gaaggcttaa
481 tcccaagcaa ctatgtgact gaaaacaaaa taactaattt agaaatatat gagtggtacc
541 atagaaacat taccagaaat caggcagaac atctattgag acaagagtct aaagaaggtg
601 catttattgt cagagattca agacatttag gatcctacac aatttccgta tttatgggag
661 ctagaagaag tacggaggct gccataaaac attatcagat aaaaaagaat gactcaggac
721 agtggtatgt ggctgaaaga cacgcctttc aatcaatccc tgagttaatc tggtatcacc
781 agcacaatgc agccggtctc atgactcgtc tccgatatcc agttgggctg atgggcagtt
841 gtttaccagc cacagctggg tttagctacg aaaagtggga gatagatcca tctgagttgg
901 cttttataaa ggagattgga agcggtcagt ttggagtggt ccatttaggt gaatggcggt
961 cacatatcca ggtagctatc aaggccatca atgaaggctc catgtctgaa gaggatttca
1021 ttgaagaggc caaagtgatg atgaaattat ctcattcaaa gctagtgcaa ctttatggag
1081 tctgtataca gcggaagccc ctttacattg tgacagagtt catggaaaat ggctgcctgc
1141 ttaactatct cagggagaat aaaggaaagc ttaggaagga aatgctactg agtgtatgcc
1201 aggatatatg tgaaggaatg gaatatctgg agaggaatgg ctatattcat agggatttgg
1261 cggcaaggaa ttgtttggtc agttcaacat gcatagtaaa aatttcagac tttggaatga
1321 caaggtacgt tttggatgat gagtatgtca gttcttttgg agccaagttc ccaatcaagt
1381 ggtcccctcc tgaagttttt cttttcaata agtacagcag taaatctgat gtctggtcat
1441 ttggagtttt aatgtgggaa gtttttacag aaggaaaaat gccttttgaa aataagtcaa
1501 atttgcaagt cgtggaagct atttctgaag gcttcaggct atatcgccct cacctggcac
1561 caatgtccat atatgaagtc atgtacagct gctggcatga gaaacctgaa ggccgcccta
1621 catttgcgga gctgctgcgg gctgtcacag agattgcgga aacctggtga ccggaaacag
1681 aatgccaacc caaagagtca tcttgcaaaa ctgtcattta ttgtgaatat cttcaccata
1741 tggggtcact tatggtgaat atctttcttc agagttgctg actcttgaaa acagtgcaaa
1801 gatcacagtt tttaaaagtt ttaaaaattt aagaatattc acacaatcgt ttttctatgt
1861 gtgagaggga tttgcacact cttatttttc tgtaaaatat ttcacatccc aaatgtgaag
1921 aagtgaaaaa gacttcgcag cagtcttcat tgtggtgctc ttcatgatca tagccccagg
1981 aacccttgag gttcttcttc acaaggctga gagtgcttcc ttcttgaaga cgagtgtcat
2041 tcatcacttc agtgatccat gcatagaata tgaaaataaa ttcttccaac tcatgggata
2101 aaggggactc ccttgaagaa tttcatgttt ttgggctgta tagctcttta cagaaaatgc
2161 acctttataa atcacatgaa tgttagtatt ctggaaatgt cttttgttaa tataatcttc
2221 ccatgttatt taacaaattg tttttgcaca tatctgatta tattgaaagc agtttttttg
2281 cattcgagtt ttaaacactg ttataaaatg tagccaaagc tcacctttga acagatcccg
2341 gtgacattct atttccagga aaatccggaa cctgatttta gttctgtgat tttacacttt
2401 ttacatgtga gattggacag tttcagaggc cttattttgt catactaagt gtctcctgta
2461 attttcagga agatgatttg ttctttccag aagaggagac aaaagcaaga tagccaaatg
2521 tgacatcaag ctccattgtt tcggaaatcc aggattttga attc
//