LOCUS HUMPGE2REP 1515 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human prostaglandin receptor (PGE-2) mRNA, complete cds.
ACCESSION L26976
VERSION L26976.1
KEYWORDS prostaglandin receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1515)
AUTHORS Yang,J., Xia,M., Goetzl,E.J. and An,S.
TITLE Cloning and expression of the EP3-subtype of human receptors for
prostaglandin E2
JOURNAL Biochem. Biophys. Res. Commun. 198 (3), 999-1006 (1994)
PUBMED 8117308
COMMENT On Apr 19, 1994 this sequence version replaced gi:435051.
Original source text: Homo sapiens adult kidney cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1515
/db_xref="H-InvDB:HIT000192709"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="kidney"
/dev_stage="adult"
gene 1..1515
/gene="PGE2-R"
CDS 140..1312
/gene="PGE2-R"
/function="binding to PGE2, decreasing cAMP"
/standard_name="PGE2-R, EP3"
/note="putative"
/codon_start=1
/product="prostaglandin receptor"
/protein_id="AAA60076.1"
/translation="MKETRGYGGDAPFCTRLNHSYTGMWAPDGSAEARGNLTRPPGSG
EDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVG
QLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIR
APHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNG
TSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRI
TTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRL
ASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER"
BASE COUNT 277 a 467 c 408 g 363 t
ORIGIN
1 gatcgtgtag gccggccgca ccatgggggg cagcccagcc cagccgcggt aaacgccgac
61 ctccgccgcc gcccgcgccg cgtctgcccc ctccgctgcg gctctctgga cgccatcccc
121 tcctcacctc gaagccaaca tgaaggagac ccggggctac ggaggggatg cccccttctg
181 cacccgcctc aaccactcct acacaggcat gtgggcgccc gacggttccg ccgaggcgcg
241 gggcaacctc acgcgccctc cagggtctgg cgaggattgc ggatcggtgt ccgtggcctt
301 cccgatcacc atgctgctca ctggtttcgt gggcaacgca ctggccatgc tgcttgtgtc
361 gcgcagctac cggcgccggg agagcaagcg caagaagtcc ttcctgctgt gcatcggctg
421 gctggcgctc accgacctgg tcgggcagct tctcaccacc ccggtcgtca tcgtcgtgta
481 cctgtccaag cagcgttggg agcacatcga cccgtcgggg cggctctgca cctttttcgg
541 gctgaccatg actgttttcg ggctctcctc gttgttcatc gccagcgcca tggcggtcga
601 gcgggcgctg gccatcaggg cgccgcactg gtatgcgagc cacatgaaga cgcgtgccac
661 ccgcgctgtg ctgctcggcg tgtggctggc cgtgctcgcc ttcgccctgc tgccggtgct
721 gggcgtgggc cagtacaccg tccagtggcc cgggacgtgg tgcttcatca gcaccgggcg
781 agggggcaac gggactagct cttcgcataa ctggggcaac cttttcttcg cctctgcctt
841 tgccttcctg gggctcttgg cgctgacagt caccttttcc tgcaacctgg ccaccattaa
901 ggccctggtg tcccgctgcc gggccaaggc cacggcatct cagtccagtg cccagtgggg
961 ccgcatcacg accgagacgg ccattcagct tatggggatc atgtgcgtgc tgtcggtctg
1021 ctggtctccg ctcctgataa tgatgttgaa aatgatcttc aatcagacat cagttgagca
1081 ctgcaagaca cacacggaga agcagaaaga atgcaacttc ttcttaatag ctgttcgcct
1141 ggcttcactg aaccagatct tggatccttg ggtttacctg ctgttaagaa agatccttct
1201 tcgaaagttt tgccagatca ggtaccacac aaacaactat gcatccagct ccacctcctt
1261 accctgccag tgttcctcaa ccttgatgtg gagcgaccat ttggaaagat aatgaaagaa
1321 cggagttgga cattttattg caattcctgc ttccctgaat ttgcatattt cttcccacct
1381 gagaaggata attatatatt ttaatttgga ttatttcttc attttatctt ttatttaatg
1441 attgttttgt cagtaatacc catggagatc aaatttatta ttataatcca tgcctctgaa
1501 tattagattg gtttc
//