LOCUS HUMEPOHYDB 1777 bp mRNA linear HUM 07-NOV-1994
DEFINITION Homo sapiens p53/HEH epoxide hydrolase (EPHX) mRNA, complete cds.
ACCESSION L25879
VERSION L25879.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1777)
AUTHORS Hassett,C., Aicher,L., Sidhu,J.S. and Omiecinski,C.J.
TITLE Human microsomal epoxide hydrolase: genetic polymorphism and
functional expression in vitro of amino acid variants
JOURNAL Hum. Mol. Genet. 3 (3), 421-428 (1994)
PUBMED 7516776
COMMENT Original source text: Homo sapiens (tissue library: lambda gt11
obtained from Clontech) female adult liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1777
/db_xref="H-InvDB:HIT000192649"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1p11-qter"
/sex="female"
/tissue_type="liver"
/dev_stage="adult"
/tissue_lib="lambda gt11 obtained from Clontech"
gene 1..1777
/gene="EPHX"
CDS 197..1564
/gene="EPHX"
/EC_number="3.3.2.9"
/codon_start=1
/product="epoxide hydrolase"
/protein_id="AAA52390.1"
/db_xref="GDB:G00-119-876"
/translation="MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAARE
DDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFD
WKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKI
IPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQ
EFYIQGGDWGSLICTNMAQLVPSHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTE
RDVELLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTN
TEFRYLEDGGLERKFSLDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKV
YVPTGFSAFPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLS
VLERQ"
regulatory 1562..1564
/regulatory_class="terminator"
/gene="EPHX"
regulatory 1759..1764
/regulatory_class="polyA_signal_sequence"
/gene="EPHX"
/note="noncanonical poly A signal sequence"
BASE COUNT 397 a 524 c 458 g 398 t
ORIGIN
1 acaggccctt agagcatcgc caggtgcaga gctccacagc tctctttccc aaggagtaat
61 cagagggtga gaacgtggag cctggtggac aggtgaaagc actgggatct ttctgcccag
121 aaaggggaaa gttgcacatt tatatcctag agggaagcga cagcagtgct tctccctgtg
181 ctgaggtaca ggagccatgt ggctagaaat cctcctcact tcagtgctgg gctttgccat
241 ctactggttc atctcccggg acaaagagga aactttgcca cttgaagatg ggtggtgggg
301 gccaggcacg aggtccgcag ccagggagga cgacagcatc cgccctttca aggtggaaac
361 gtcagatgag gagatccacg acttacacca gaggatcgat aagttccgtt tcaccccacc
421 tttggaggac agctgcttcc actatggctt caactccaac tacctgaaga aagtcatctc
481 ctactggcgg aatgaatttg actggaagaa gcaggtggag attctcaaca gataccctca
541 cttcaagact aaaattgaag ggctggacat ccacttcatc cacgtgaagc ccccccagct
601 gcccgcaggc cataccccga agcccttgct gatggtgcac ggctggcccg gctctttcta
661 cgagttttat aagatcatcc cactcctgac tgaccccaag aaccatggcc tgagcgatga
721 gcacgttttt gaagtcatct gcccttccat ccctggctat ggcttctcag aggcatcctc
781 caagaagggg ttcaactcgg tggccaccgc caggatcttt tacaagctga tgctgcggct
841 gggcttccag gaattctaca ttcaaggagg ggactggggg tccctgatct gcactaatat
901 ggcccagctg gtgcccagcc acgtgaaagg cctgcacttg aacatggctt tggttttaag
961 caacttctct accctgaccc tcctcctggg acagcgtttc gggaggtttc ttggcctcac
1021 tgagagggat gtggagctgc tgtaccccgt caaggagaag gtattctaca gcctgatgag
1081 ggagagcggc tacatgcaca tccagtgcac caagcctgac accgtaggct ctgctctgaa
1141 tgactctcct gtgggtctgg ctgcctatat tctagagaag ttttccacct ggaccaatac
1201 ggaattccga tacctggagg atggaggcct ggaaaggaag ttctccctgg acgacctgct
1261 gaccaacgtc atgctctact ggacaacagg caccatcatc tcctcccagc gcttctacaa
1321 ggagaacctg ggacagggct ggatgaccca gaagcatgag cggatgaagg tctatgtgcc
1381 cactggcttc tctgccttcc cttttgagct attgcacacg cctgaaaagt gggtgaggtt
1441 caagtaccca aagctcatct cctattccta catggttcgt gggggccact ttgcggcctt
1501 tgaggagccg gagctgctcg cccaggacat ccgcaagttc ctgtcggtgc tggagcggca
1561 atgacccacc cctctccccc cgcctgccac ctccccccac aagtgccctc caggcttttc
1621 ttggggaaga tacccctttt ctgaggaatg agtttgcctc cgtcccctgc ccatgctggg
1681 agcccacgct caccccctca cccctccaag ctcactcccc aacccccaac tccgtgtggt
1741 aagcaacatg gctttgatga taaacgactt tactcta
//