LOCUS HUMNRF1 2969 bp mRNA linear HUM 23-MAR-1994
DEFINITION Homo sapiens nuclear respiratory factor-1 (NRF-1) mRNA, complete
cds.
ACCESSION L22454
VERSION L22454.1
KEYWORDS nuclear respiratory factor-1; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1630)
AUTHORS Virbasius,C.A., Virbasius,J.V. and Scarpulla,R.C.
TITLE NRF-1, an activator involved in nuclear-mitochondrial interactions,
utilizes a new DNA-binding domain conserved in a family of
developmental regulators
JOURNAL Genes Dev. 7 (12A), 2431-2445 (1993)
PUBMED 8253388
REFERENCE 2 (bases 1 to 2969)
AUTHORS Virbasius,J.V.
TITLE Direct Submission
JOURNAL Submitted (27-JUL-1993) Joseph V. Virbasius, Northwestern
University Medical School, Cell, Molecular and Structural Biology,
303 E. Chicago Ave., Chicago, IL 60611, USA
COMMENT Original source text: Homo sapiens (human).
FEATURES Location/Qualifiers
source 1..2969
/db_xref="H-InvDB:HIT000192510"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
CDS 119..1630
/function="transcription factor"
/standard_name="NRF-1"
/experiment="experimental evidence, no additional details
recorded"
/codon_start=1
/product="nuclear respiratory factor-1"
/protein_id="AAA16918.1"
/translation="MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDS
PSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPS
IRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYK
SMILEDLESALAEHAPAPQEVNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTG
RGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGRE
DLLYAFEDQQTQTQATATHSIAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADA
SELPTTVTVAQVNYSAVADGEVEQNWATLQGGEMTIQTTQASEATQAVASLAEAAVAA
SQEMQQGATVTMALNSEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDANG
LVQIPVSMYQTVVTSLAQGNGPVQVAMAPVTTRISDSAVTMDGQAVEVVTLEQ"
BASE COUNT 767 a 697 c 804 g 701 t
ORIGIN
1 agcgctgccg cttctgagtt cctggtccag aactttacac agaaaaggtg ctcaaaggat
61 atttgtttaa tgaatgtggt atgctgacat ttaaacagga caaaacttgt agaacttcat
121 ggaggaacac ggagtgaccc aaaccgaaca tatggctacc atagaagcac atgcagtggc
181 ccagcaagtg cagcaggtcc atgtggctac ttacaccgag catagtatgc tgagtgctga
241 tgaagactcg ccttcttcgc ccgaggacac ctcttacgat gactcagata tactcaactc
301 cacagcagct gatgaggtga cagctcatct ggcagctgca ggtcctgtgg gaatggccgc
361 tgctgctgct gtggcaacag gaaagaaacg gaaacggcct catgtatttg agtctaatcc
421 atctatccgg aagaggcaac aaacacgttt gcttcggaaa cttcgagcca cgttagatga
481 atatactact cgtgtgggac agcaagctat tgtcctctgt atctcaccct ccaaacctaa
541 ccctgtcttt aaagtgtttg gtgcagcacc tttggagaat gtggtgcgta agtacaagag
601 catgatcctg gaagacctgg agtctgctct ggcagaacac gcccctgcgc cacaggaggt
661 taactcagaa ctgccgcctc tcaccatcga cggaattcca gtctctgtgg acaaaatgac
721 ccaggcccag cttcgggcat ttatcccaga gatgctcaag tactctacag gtcggggaaa
781 accaggctgg gggaaagaaa gctgcaagcc catctggtgg cctgaagata tcccctgggc
841 aaatgtccgg agtgatgtcc gcacagaaga gcaaaagcag agggtttcat ggacccaggc
901 actacggacc atagttaaaa actgttataa acagcatggg cgggaagacc ttttgtatgc
961 ctttgaagat cagcaaacgc aaacacaggc cacagccaca catagtatag ctcatcttgt
1021 accatcacag actgtagtcc agacttttag taaccctgat ggcactgtct cacttatcca
1081 ggttggtacg ggggcaacag tagccacatt ggctgatgct tcagaattgc caaccacggt
1141 caccgttgcc caagtgaatt attctgccgt ggctgatgga gaggtggaac aaaattgggc
1201 cacgttacag ggaggtgaga tgaccatcca gacgacgcaa gcatcagagg ccacccaggc
1261 ggtggcatcg ttggcagagg ccgcagtggc agcttctcag gagatgcagc agggagctac
1321 agtcactatg gcgcttaaca gcgaagctgc cgcccatgct gtcgccaccc tggctgaggc
1381 caccttacaa ggtgggggac agatcgtctt gtctggggaa accgcagcag ccgtcggagc
1441 acttactgga gtccaagatg ctaatggcct ggtccagatc cctgtgagca tgtaccagac
1501 tgtggtgacc agcctcgccc agggcaacgg accagtgcag gtggccatgg cccctgtgac
1561 caccaggata tcagacagcg cagtcaccat ggacggccaa gctgtggagg tggtgacatt
1621 ggaacagtga catacagcca tattatggca tcgttttcta gtctacttca aaatttttta
1681 cacgtttgca gaggtgcaat caaatggaat taagtctctc gactttggaa ggaaagtttt
1741 gttaaccttt tttttttaaa aggaagaaag cggattttgg aattgcattt tttaaagcac
1801 cactcttgat tttctgggat tggtgaagaa actgcattgt caatttcact gtcccaaaaa
1861 agccaaattg tggcaggact tctttctgcg gaaatgtgtg tgtatactta tgtgtgtgca
1921 tgtgtgagtg tgaatatatg tatatgtgta catatggaca tacacattta caatatatat
1981 aaagtatata tatacatata tatatatatg tatgaaaccc gcatggaatt atctgtatga
2041 aatcaaggtg cgctgtggaa acaataattc acccagttta gtgggtggta gggtacgtgg
2101 ccagacacag tcacccagtt tttgttcata ccagggtcat gcgttgagct actgacaaac
2161 tcaggcggag gtgaccatgc ccttcaccaa agctgcctcc cagtggccac acagaactct
2221 ccctgctgga ctcacctgag gaaagaggct ccagcatggg gtgggtcaga gatgtgcttg
2281 caaggtccag ggactgcgtg gtctgccagc tgagatgctc ctcgggctgg cccaggtgct
2341 gaccttgcca caggcagatg aatgtcttga aagctcccgg gcctcagcct cccatctcct
2401 ctccttccca ggaatccttg atctcatgac tattaaatgt tgctctggtt taaggtcagt
2461 cctgaattgc tcgtatatat gaactgaagg taaccgaagt attaggggtt tgaggagtcg
2521 tcgtgtaagt gtgcttgtgt gtgtgcgtgc atggtggggg agaggatggg aagggggcgg
2581 gggcagtgga agggaaagga aggaaagaaa aatcgtccta gaccaggata cacccgtggg
2641 agcaattttc tctactgtct gtagcttcac agaggaggcg ctggaatgaa caagaagaga
2701 catctggtct gtggccacag caccctgaac gcccctgatc ttgtgtgatc ttggaagcta
2761 agcttggttg ggcccggtca gtacgcagaa gggaagaagg gacacctggc catagaaaac
2821 agctgagggt gtttgctgtg ttcctggatc aggccctgct tcagaaggga ctcctggagg
2881 cccatgttcc ttgatgcaac ctcctggccc aggccgggag cagcttgcct cctcagaggt
2941 gttgactatc tgggtgttct tggtaacaa
//