LOCUS HUMPDEA 3705 bp mRNA linear HUM 09-DEC-1993
DEFINITION Human phosphodiesterase mRNA, complete cds.
ACCESSION L20965
VERSION L20965.1
KEYWORDS phosphodiesterase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3705)
AUTHORS Bolger,G., Michaeli,T., Martins,T., St John,T., Steiner,B.,
Rodgers,L., Riggs,M., Wigler,M. and Ferguson,K.
TITLE A family of human phosphodiesterases homologous to the dunce
learning and memory gene product of Drosophila melanogaster are
potential targets for antidepressant drugs
JOURNAL Mol. Cell. Biol. 13 (10), 6558-6571 (1993)
PUBMED 8413254
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3705
/db_xref="H-InvDB:HIT000192441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 116..2776
/codon_start=1
/product="phosphodiesterase"
/protein_id="AAA03588.1"
/translation="MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQ
QRGYSDSAERAERERQPHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGG
GSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKT
MSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVC
KATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEM
SRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQ
ITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLT
CIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLA
TPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVT
SSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERG
MEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSA
IRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLS
GVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSS
REEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAK
RACSACAGTFGEDTSALPAPGGGGSGGDPT"
BASE COUNT 787 a 1177 c 1037 g 704 t
ORIGIN
1 ggaattcccg gccgggcgca cccgcggggc cctgggctcg ctggcttgcg cgcagctgag
61 cggggtgtag gttggaaggg ccagggcccc tggggcgcaa gtgggggccg gcgccatgga
121 acccccgacc gtcccctcgg aaaggagcct gtctctgtca ctgcccgggc cccgggaggg
181 ccaggccacc ctgaagcctc ccccgcagca cctgtggcgg cagcctcgga cccccatccg
241 tatccagcag cgcggctact ccgacagcgc ggagcgcgcc gagcgggagc ggcagccgca
301 ccggcccata gagcgcgccg atgccatgga caccagcgac cggcccggcc tgcgcacgac
361 ccgcatgtcc tggccctcgt ccttccatgg cactggcacc ggcagcggcg gcgcgggcgg
421 aggcagcagc aggcgcttcg aggcagagaa tgggccgaca ccatctcctg gccgcagccc
481 cctggactcg caggcgagcc caggactcgt gctgcacgcc ggggcggcca ccagccagcg
541 ccgggagtcc ttcctgtacc gctcagacag cgactatgac atgtcaccca agaccatgtc
601 ccggaactca tcggtcacca gcgaggcgca cgctgaagac ctcatcgtaa caccatttgc
661 tcaggtgctg gccagcctcc ggagcgtccg tagcaacttc tcactcctga ccaatgtgcc
721 cgttcccagt aacaagcggt ccccgctggg cggccccacc cctgtctgca aggccacgct
781 gtcagaagaa acgtgtcagc agttggcccg ggagactctg gaggagctgg actggtgtct
841 ggagcagctg gagaccatgc agacctatcg ctctgtcagc gagatggcct cgcacaagtt
901 caaaaggatg ttgaaccgtg agctcacaca cctgtcagaa atgagcaggt ccggaaacca
961 ggtctcagag tacatttcca caacattcct ggacaaacag aatgaagtgg agatcccatc
1021 acccacgatg aaggaacgag aaaaacagca agcgccgcga ccaagaccct cccagccgcc
1081 cccgccccct gtaccacact tacagcccat gtcccaaatc acagggttga aaaagttgat
1141 gcatagtaac agcctgaaca actctaacat tccccgattt ggggtgaaga ccgatcaaga
1201 agagctcctg gcccaagaac tggagaacct gaacaagtgg ggcctgaaca tcttttgcgt
1261 gtcggattac gctggaggcc gctcactcac ctgcatcatg tacatgatat tccaggagcg
1321 ggacctgctg aagaaattcc gcatcccggt ggacacgatg gtgacataca tgctgacgct
1381 ggaggatcac taccacgctg acgtggccta ccataacagc ctgcacgcag ctgacgtgct
1441 gcagtccacc cacgtactgc tggccacgcc tgcactagat gcagtgttca cggacctgga
1501 gattctcgcc gccctcttcg cggctgccat ccacgatgtg gatcaccctg gggtctccaa
1561 ccagttcctc atcaacacca attcggagct ggcgctcatg tacaacgatg agtcggtgct
1621 cgagaatcac cacctggccg tgggcttcaa gctgctgcag gaggacaact gcgacatctt
1681 ccagaacctc agcaagcgcc agcggcagag cctacgcaag atggtcatcg acatggtgct
1741 ggccacggac atgtccaagc acatgaccct cctggctgac ctgaagacca tggtggagac
1801 caagaaagtg accagctcag gggtcctcct gctagataac tactccgacc gcatccaggt
1861 cctccggaac atggtgcact gtgccgacct cagcaacccc accaagccgc tggagctgta
1921 ccgccagtgg acagaccgca tcatggccga gttcttccag cagggtgacc gagagcgcga
1981 gcgtggcatg gaaatcagcc ccatgtgtga caagcacact gcctccgtgg agaagtctca
2041 ggtgggtttt attgactaca ttgtgcaccc attgtgggag acctgggcgg accttgtcca
2101 cccagatgcc caggagatct tggacacttt ggaggacaac cgggactggt actacagcgc
2161 catccggcag agcccatctc cgccacccga ggaggagtca agggggccag gccacccacc
2221 cctgcctgac aagttccagt ttgagctgac gctggaggag gaagaggagg aagaaatatc
2281 aatggcccag ataccgtgca cagcccaaga ggcattgact gcgcagggat tgtcaggagt
2341 cgaggaagct ctggatgcaa ccatagcctg ggaggcatcc ccggcccagg agtcgttgga
2401 agttatggca caggaagcat ccctggaggc cgagctggag gcagtgtatt tgacacagca
2461 ggcacagtcc acaggcagtg cacctgtggc tccggatgag ttctcgtccc gggaggaatt
2521 cgtggttgct gtaagccaca gcagcccctc tgccctggct cttcaaagcc cccttctccc
2581 tgcttggagg accctgtctg tttcagagca tgccccgggc ctcccgggcc tcccctccac
2641 ggcggccgag gtggaggccc aacgagagca ccaggctgcc aagagggctt gcagtgcctg
2701 cgcagggaca tttggggagg acacatccgc actcccagct cctggtggcg gggggtcagg
2761 tggagaccct acctgatccc cagacctctg tccctgttcc cctccactcc tcccctcact
2821 cccctgctcc cccgaccacc tcctcctctg cctcaaagac tcttgtcctc ttgtccctcc
2881 tgagaaaaaa gaaaacgaaa agtggggttt ttttctgttt tctttttttc ccctttcccc
2941 ctgcccccac ccacggggcc tttttttgga ggtgggggct ggggaatgag gggctgaggt
3001 cccggaagga ttttattttt ttgaatttta attgtaacat ttttagaaaa agaacaaaaa
3061 aagaaaaaaa aaagaaagaa acacagcaac tgtagatgct cctgttcctg gttcccgctt
3121 tccacttcca aatccctccc ctcaccttcc cccactgccc cccaagttcc aggctcagtc
3181 ttccagccgc ctggggagtc tctacctggg cccaagcagg tgtggggcct ccttctgggc
3241 ttttcttctg aatttagagg atttctagaa cgtggtcagg aatagccatt ctaggcgggg
3301 ctggggccag ggtggggggc agtcactgtg ggaggtccca gctccagccc ccctctggtt
3361 tgctgcctcc tctcccctct aaaaaagtct tccgcttgat tttgcacaat cccggcgata
3421 ctcctggcga tactgactag aagtcaggga gctgggggag ctgttcactt taggatacgg
3481 ggggatggaa gggagcgttc acaccgccag cctcgggcct gggatttgag gagggcccta
3541 gacctcctcc actctccatc ccctttccct tccactttgg gttcactttg aattttctcc
3601 gttttttggg gcagtggctc tgatccactc acccccccgc cccgtaagtt atagccactg
3661 tggaaagtag tatgaaagtt cctcaagaaa ctaaaaatgg aattc
//