LOCUS HUMEMMPRIN 1490 bp mRNA linear HUM 22-JAN-1997
DEFINITION Human extracellular matrix metalloproteinase inducer gene, complete
cds.
ACCESSION L20471
VERSION L20471.1
KEYWORDS extracellular matrix metalloproteinase inducer.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1490)
AUTHORS DeCastro,R., Zhang,Y., Guo,H., Kataoka,H., Gordon,M.K., Toole,B.
and Biswas,G.
TITLE Human keratinocytes express EMMPRIN, an extracellular matrix
metalloproteinase inducer
JOURNAL J. Invest. Dermatol. 106 (6), 1260-1265 (1996)
PUBMED 8752667
FEATURES Location/Qualifiers
source 1..1490
/db_xref="H-InvDB:HIT000192422"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="keratinocyte"
CDS 46..855
/note="EMMPRIN"
/codon_start=1
/product="extracellular matrix metalloproteinase inducer"
/protein_id="AAB41120.1"
/translation="MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLN
DSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLH
GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFV
SSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAE
VLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS"
sig_peptide 46..108
/note="EMMPRIN"
mat_peptide 109..852
/product="extracellular matrix metalloproteinase inducer"
/note="EMMPRIN; transmenbrane domain = bp 661-732;
extracellular domain, bp 109-660."
BASE COUNT 281 a 465 c 440 g 304 t
ORIGIN
1 cggcggttgg aggttgtacg cggattccgg cgaggaatag gaatcatggc ggctgcgctg
61 ttcgtgctgc tgggattcgc gctgctgggc acccacggag cctccggggc tgctggcaca
121 gtcttcacta ccgtagaaga ccttggctcc aagatactcc tcacctgctc cttgaatgac
181 agcgccacag aggtcacagg gcaccgctgg ctgaaggggg gcgtggtgct gaaggaggac
241 gcgctgcccg gccagaaaac ggagttcaag gtggactccg acgaccagtg gggagagtac
301 tcctgcgtct tcctccccga gcccatgggc acggccaaca tccagctcca cgggcctccc
361 agagtgaagg ccgtgaagtc gtcagaacac atcaacgagg gggagacggc catgctggtc
421 tgcaagtcag agtccgtgcc acctgtcact gactgggcct ggtacaagat cactgactct
481 gaggacaagg ccctcatgaa cggctccgag agcaggttct tcgtgagttc ctcgcagggc
541 cggtcagagc tacacattga gaacctgaac atggaggccg atcccggcca gtaccggtgc
601 aacggcacca gctccaaggg ctccgaccag gccatcatca cgctccgcgt gcgcagccac
661 ctggccgccc tctggccctt cctgggcatc gtggctgagg tgctggtgct ggtcaccatc
721 atcttcatct acgagaagcg ccggaagccc gaggacgtcc tggatgatga cgacgccggc
781 tctgcacccc tgaagagcag cgggcagcac cagaatgaca aaggcaagaa cgtccgccag
841 aggaactctt cctgaggcag gtggcccgag gacgctccct gctccgcgtc tgcgccgccg
901 ccggagtcca ctcccagtgc ttgcaagatt ccaagttctc acctcttaaa gaaaacccac
961 cccgtagatt cccatcatac acttccttct tttttaaaaa agttgggttt tctccattca
1021 ggattctgtt ccttaggatt ttttccttct gaagtgtttc acgagagccc gggagctgct
1081 gccctgcggc cccgtctgtg gctttcagcc tctgggtctg agtcatggcc gggtgggcgg
1141 cacagccttc tccactggcc ggagtcagtg ccaggtcctt gccctttgtg gaaagtcaca
1201 ggtcacacga ggggccccgt gtcctgcctg tctgaagcca atgctgtctg gttgcgccat
1261 ttttgtgctt ttatgtttaa ttttatgagg gccacgggtc tgtgttcgac tcagcctcag
1321 ggacgactct gacctcttgg ccacagagga ctcaacttgc ccacaccgag ggcgaccccg
1381 tcacagcctc aagtcactcc caagccccct ccttgtctgt gcatccgggg gcagctctgg
1441 agggggtttg ctggggaact ggcgccatcg ccgggactcc agaaccgccg
//