LOCUS HUMVLDLR 3656 bp mRNA linear HUM 28-NOV-1994
DEFINITION Human very low density lipoprotein receptor mRNA, complete cds.
ACCESSION L20470
VERSION L20470.1
KEYWORDS very low density lipoprotein receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3656)
AUTHORS Gafvels,M.E., Caird,M., Britt,D., Jackson,C.L., Patterson,D. and
Strauss,J.F. III.
TITLE Cloning of a cDNA encoding a putative human very low density
lipoprotein/apolipoprotein E receptor and assignment of the gene to
chromosome 9pter-p23
JOURNAL Somat. Cell Mol. Genet. 19 (6), 557-569 (1993)
PUBMED 8128315
COMMENT Original source text: Homo sapiens (library: lambda ZAP) adult
skeletal muscle cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3656
/db_xref="H-InvDB:HIT000192421"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="9pter-p23"
/tissue_type="skeletal muscle"
/dev_stage="adult"
/tissue_lib="lambda ZAP"
5'UTR 1..391
CDS 392..3013
/codon_start=1
/product="very low density lipoprotein receptor"
/protein_id="AAA53684.1"
/translation="MGTSALWAVWLLLALCWAPRESGATGTGRKAKCEPSQFQCTNGR
CITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSD
ESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFT
CSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADC
SDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSR
TCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDI
SKVCNQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELIDRK
TCGDIDECQNPGICSQICINLKGGYKCECSRAYQMDLATGVCKAVGKEPSLIFTNRRD
IRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKM
IDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGTKRKFLFNSDLREPASIAVDPL
SGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQWPNGITLDLIKSRLYWLDSKLHML
SSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSEHATLV
NNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCLPAPQINDHSPKYTCSCPSGY
NVEENGRDCQSTATTVTYSETKDTNTTEISATSGLVPGGINVTTAVSEVSVPPKGTSA
AWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASV
GHTYPAISVVSTDDDLA"
sig_peptide 392..472
3'UTR 3014..3614
regulatory 3609..3614
/regulatory_class="polyA_signal_sequence"
BASE COUNT 990 a 843 c 907 g 916 t
ORIGIN
1 ctctgcgggc cgcgggtgcg ggtcgtcgct accggctctc tccgttctgt gctctcttct
61 gctctcggct ccccaccccc tctcccttcc ctcctctccc cttgcctccc ctcctctgca
121 gcgcctgcat tattttctgc ccgcagctcg gcttgcactg ctgctgcagc ccggggaggt
181 ggctgggtgg gtggggagga gactgtgcaa gttgtagggg agggggtgcc ctcttcttcc
241 ccgctccctt ccccagccaa gtggttcccc tccttctccc cctttcccct cccagccccc
301 accttcttcc tctttcggaa gggctggtaa cttgtcgtgc ggagcgaacg gcggcggcgg
361 cggcggcggc ggcaccatcc aggcgggcac catgggcacg tccgcgctct gggccgtctg
421 gctgctgctc gcgctgtgct gggcgccccg ggagagcggc gccaccggaa ccgggagaaa
481 agccaaatgt gaaccctccc aattccagtg cacaaatggt cgctgtatta cgctgttgtg
541 gaaatgtgat ggggatgaag actgtgttga cggcagtgat gaaaagaact gtgtaaagaa
601 gacgtgtgct gaatctgact tcgtgtgcaa caatggccag tgtgttccca gccgatggaa
661 gtgtgatgga gatcctgact gcgaagatgg ttcagatgaa agcccagaac agtgccatat
721 gagaacatgc cgcatacatg aaatcagctg tggcgcccat tctactcagt gtatcccagt
781 gtcctggaga tgtgatggtg aaaatgattg tgacagtgga gaagatgaag aaaactgtgg
841 caatataaca tgtagtcccg acgagttcac ctgctccagt ggccgctgca tctccaggaa
901 ctttgtatgc aatggccagg atgactgcag cgatggcagt gatgagctgg actgtgcccc
961 gccaacctgt ggcgcccatg agttccagtg cagcacctcc tcctgcatcc ccatcagctg
1021 ggtatgcgac gatgatgcag actgctccga ccaatctgat gagtccctgg agcagtgtgg
1081 ccgtcagcca gtcatacaca ccaagtgtcc agccagcgaa atccagtgcg gctctggcga
1141 gtgcatccat aagaagtggc gatgtgatgg ggaccctgac tgcaaggatg gcagtgatga
1201 ggtcaactgt ccctctcgaa cttgccgacc tgaccaattt gaatgtgagg atggcagctg
1261 catccatggc agcaggcagt gtaatggtat ccgagactgt gtcgatggtt ccgatgaagt
1321 caactgcaaa aatgtcaatc agtgcttggg ccctggaaaa ttcaagtgca gaagtggaga
1381 atgcatagat atcagcaaag tatgtaacca ggagcaggac tgcagggact ggagtgatga
1441 gcccctgaaa gagtgtcata taaacgaatg cttggtaaat aatggtggat gttctcatat
1501 ctgcaaagac ctagttatag gctacgagtg tgactgtgca gctgggtttg aactgataga
1561 taggaaaacc tgtggagata ttgatgaatg ccaaaatcca ggaatctgca gtcaaatttg
1621 tatcaactta aaaggcggtt acaagtgtga atgtagtcgt gcctatcaaa tggatcttgc
1681 tactggcgtg tgcaaggcag taggcaaaga gccaagtctg atcttcacta atcgaagaga
1741 catcaggaag attggcttag agaggaaaga atatatccaa ctagttgaac agctaagaaa
1801 cactgtggct ctcgatgctg acattgctgc ccagaaacta ttctgggccg atctaagcca
1861 aaaggctatc ttcagtgcct caattgatga caaggttggt agacatgtta aaatgatcga
1921 caatgtctat aatcctgcag ccattgctgt tgattgggtg tacaagacca tctactggac
1981 tgatgcggct tctaagacta tttcagtagc taccctagat ggaaccaaga ggaagttcct
2041 gtttaactct gacttgcgag agcctgcctc catagctgtg gacccactgt ctggctttgt
2101 ttactggtca gactggggtg aaccagctaa aatagaaaaa gcaggaatga atggattcga
2161 tagacgtcca ctggtgacag cggatatcca gtggcctaac ggaattacac ttgaccttat
2221 aaaaagtcgc ctctattggc ttgattctaa gttgcacatg ttatccagcg tggacttgaa
2281 tggccaagat cgtaggatag tactaaagtc tctggagttc ctagctcatc ctcttgcact
2341 aacaatattt gaggatcgtg tctactggat agatggggaa aatgaagcag tctatggtgc
2401 caataaattc actggatcag agcatgccac tctagtcaac aacctgaatg atgcccaaga
2461 catcattgtc tatcatgaac ttgtacagcc atcaggtaaa aattggtgtg aagaagacat
2521 ggagaatgga ggatgtgaat acctatgcct gccagcacca cagattaatg atcactctcc
2581 aaaatatacc tgttcctgtc ccagtgggta caatgtagag gaaaatggcc gagactgtca
2641 aagtactgca actactgtga cttacagtga gacaaaagat acgaacacaa cagaaatttc
2701 agcaactagt ggactagttc ctggagggat caatgtgacc acagcagtat cagaggtcag
2761 tgttccccca aaagggactt ctgccgcatg ggccattctt cctctcttgc tcttagtgat
2821 ggcagcagta ggtggctact tgatgtggcg gaattggcaa cacaagaaca tgaaaagcat
2881 gaactttgac aatcctgtgt acttgaaaac cactgaagag gacctctcca tagacattgg
2941 tagacacagt gcttctgttg gacacacgta cccagcaata tcagttgtaa gcacagatga
3001 tgatctagct tgacttctgt gacaaatgtt gacctttgag gtctaaacaa ataatacccc
3061 cgtcggaatg gtaaccgagc cagcagctga agtctctttt tcttcctctc ggctggaaga
3121 acatcaagat acctttgcgt ggatcaagct tgctgtactt gaccgttttt atattacttt
3181 tgtaaatatt cttgtccaca ttctacttca gctttggatg tggttaccga gtatctgtaa
3241 cccttgaatt tctagacagt attgccacct ctggccaaat atgcactttc cctagaaagc
3301 catattccag cagtgaaact tgtgctatag tgtataccac ctgtacatac attgtatagg
3361 ccatctgtaa atatcccaga gaacaatcac tattcttaag cactttgaaa atatttctat
3421 gtaaattatt gtaaactttt tcaatggttg ggacaatggc aataggacaa aacgggttac
3481 taagatgaaa ttgccaaaaa aatttataaa ctaattttgg tacgtatgaa tgatatcttt
3541 gacctcaatg gaggtttgca aagactgagt gttcaaacta ctgtacattt tttttcaagt
3601 gctaaaaaat taaaccaagc agcttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//