LOCUS HUMTRP2A 2270 bp mRNA linear HUM 17-AUG-1994
DEFINITION Homo sapiens TRP-2/dopachrome tautomerase (Tyrp-2) mRNA, complete
cds.
ACCESSION L18967
VERSION L18967.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2270)
AUTHORS Cassady,J.L. and Sturm,R.A.
TITLE Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA
JOURNAL Gene 143 (2), 295-298 (1994)
PUBMED 8206391
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2270
/db_xref="H-InvDB:HIT000192316"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="A2058"
/cell_type="melanoma"
/tissue_lib="Uni-ZAP-XR from Stratagene"
gene 1..2270
/gene="Tyrp-2"
CDS 385..1944
/gene="Tyrp-2"
/codon_start=1
/product="tyrosine-related protein 2"
/protein_id="AAA20870.1"
/translation="MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRL
GAESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFA
GYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITT
QHWLGLLGPNGTQPQFANCSVYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVT
WHRYHLLCLERDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRN
SRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKF
DNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIF
VVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQ
LGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLMET
HLSSKRYTEEA"
sig_peptide 385..453
/gene="Tyrp-2"
mat_peptide 454..1941
/gene="Tyrp-2"
/product="tyrosine-related protein 2"
BASE COUNT 638 a 506 c 534 g 592 t
ORIGIN
1 gagagggttt agaaatacca gcataataag tagtatgact gggtgctctg taaattaact
61 caattagaca aagcctgact taacggggga agatggtgag aagcgctacc ctcattaaat
121 ttggttgtta gaggcgcttc taaggaaatt aagtctgtta gttgtttgaa tcacataaaa
181 ttgtgtgtgc acgttcatgt acacatgtgc acacatgtaa cctctgtgat tcttgtgggt
241 atttttttaa gaagaaagga atagaaagca aagaaaaata aaaaatactg aaaagaaaag
301 actgaaagag tagaagataa ggagaaaagt acgacagaga caaggaaagt aagagagaga
361 gagagctctc ccaattataa agccatgagc cccctttggt gggggtttct gctcagttgc
421 ttgggctgca aaatcctgcc aggagcccag ggtcagttcc cccgagtctg catgacggtg
481 gacagcctag tgaacaagga gtgctgccca cgcctgggtg cagagtcggc caatgtctgt
541 ggctctcagc aaggccgggg gcagtgcaca gaggtgcgag ccgacacaag gccctggagt
601 ggtccctaca tcctacgaaa ccaggatgac cgtgagctgt ggccaagaaa attcttccac
661 cggacctgca agtgcacagg aaactttgcc ggctataatt gtggagactg caagtttggc
721 tggaccggtc ccaactgcga gcggaagaaa ccaccagtga ttcggcagaa catccattcc
781 ttgagtcctc aggaaagaga gcagttcttg ggcgccttag atctcgcgaa gaagagagta
841 caccccgact acgtgatcac cacacaacac tggctgggcc tgcttgggcc caatggaacc
901 cagccgcagt ttgccaactg cagtgtttat gatttttttg tgtggctcca ttattattct
961 gttagagata cattattagg accaggacgc ccctacaggg ccatagattt ctcacatcaa
1021 ggacctgcat ttgttacctg gcaccggtac catttgttgt gtctggaaag agatctccag
1081 cgactcattg gcaatgagtc ttttgctttg ccctactgga actttgccac tgggaggaac
1141 gagtgtgatg tgtgtacaga ccagctgttt ggggcagcga gaccagacga tccgactctg
1201 attagtcgga actcaagatt ctccagctgg gaaactgtct gtgatagctt ggatgactac
1261 aaccacctgg tcaccttgtg caatggaacc tatgaaggtt tgctgagaag aaatcaaatg
1321 ggaagaaaca gcatgaaatt gccaacctta aaagacatac gagattgcct gtctctccag
1381 aagtttgaca atcctccctt cttccagaac tctaccttca gtttcaggaa tgctttggaa
1441 gggtttgata aagcagatgg gactctggat tctcaagtga tgagccttca taatttggtt
1501 cattccttcc tgaacgggac aaacgctttg ccacattcag ccgccaatga tcccattttt
1561 gtggttcttc attcctttac tgatgccatc tttgatgagt ggatgaaaag atttaatcct
1621 cctgcagatg cctggcctca ggagctggcc cctattggtc acaatcggat gtacaacatg
1681 gttcctttct tccctccagt gactaatgaa gaactctttt taacctcaga ccaacttggc
1741 tacagctatg ccatcgatct gccagtttca gttgaagaaa ctccaggttg gcccacaact
1801 ctcttagtag tcatgggaac actggtggct ttggttggtc tttttgtgct gttggctttt
1861 cttcaatata gaagacttcg aaaaggatat acacccctaa tggagacaca tttaagcagc
1921 aagagataca cagaagaagc ctagggtgct catgccttac ctaagagaag aggttggcca
1981 agccacagtt ctgacgctga caataaagga actaatcctc actgttcctt cttgagttga
2041 agatctttga cataggttct tctatagtga tgatgatctc attcagaaga tgcttagctg
2101 tagtttccgc tttgcttgct tgtttaacaa acccaactaa agtgcttgag gctacctcta
2161 ccttcaaata aagatagacc tgacaatttg tgatatctaa taataacccc ccccccaata
2221 ttgattaagc ctcctccttt tctgaaagca tttaaaaaaa aaaaaaaaaa
//