LOCUS HUMGRK5A 2557 bp mRNA linear HUM 31-DEC-1994
DEFINITION Human G protein-coupled receptor kinase (GRK5) mRNA, complete cds.
ACCESSION L15388
VERSION L15388.1
KEYWORDS G-protein coupled receptor kinase; G-protein receptor kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2557)
AUTHORS Kunapuli,P. and Benovic,J.L.
TITLE Cloning and expression of GRK5: a member of the G protein-coupled
receptor kinase family
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 90 (12), 5588-5592 (1993)
PUBMED 7685906
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2557
/db_xref="H-InvDB:HIT000192280"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2557
/gene="GRK5"
CDS 221..1993
/gene="GRK5"
/codon_start=1
/product="G protein-coupled receptor kinase"
/protein_id="AAA58620.1"
/translation="MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCED
LRRTIDRDYCSLCDKQPIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKG
KEIMTKYLTPKSPVFIAQVGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHE
YLDSMFFDRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLE
KKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIY
NMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAV
KIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKV
KREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRN
MNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTGSVS
IPWQNEMIETECFKELNVFGPNGTLPPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSS
PSSKTSFNHHINSNHVSSNSTGSS"
BASE COUNT 666 a 639 c 726 g 526 t
ORIGIN
1 cagagggagg aagaagcggc ggcgcggcgg cggcggctcc tctttgcaga gggggaaact
61 cttgggctga gagcaggaac aacgcggtag gcaaggcggg ctgctggctc ccccggctcc
121 ggcagcagcg gcggcagccc gagcagcggc agcagcagcg gcagcacccc aggcgctgac
181 agccccgccg gccggctccg ttgctgaccg ccgactgtca atggagctgg aaaacatcgt
241 ggccaacacg gtcttgctga aagccaggga agggggcgga ggaaagcgca aagggaaaag
301 caagaagtgg aaagaaatcc tgaagttccc tcacattagc cagtgtgaag acctccgaag
361 gaccatagac agagattact gcagtttatg tgacaagcag ccaatcggga ggctgctttt
421 ccggcagttt tgtgaaacca ggcctgggct ggagtgttac attcagttcc tggactccgt
481 ggcagaatat gaagttactc cagatgaaaa actgggagag aaagggaagg aaattatgac
541 caagtacctc accccaaagt cccctgtttt catagcccaa gttggccaag acctggtctc
601 ccagacggag gagaagctcc tacagaagcc gtgcaaagaa ctcttttctg cctgtgcaca
661 gtctgtccac gagtacctga ggggagaacc attccacgaa tatctggaca gcatgttttt
721 tgaccgcttt ctccagtgga agtggttgga aaggcaaccg gtgaccaaaa acactttcag
781 gcagtatcga gtgctaggaa aagggggctt cggggaggtc tgtgcctgcc aggttcgggc
841 cacgggtaaa atgtatgcct gcaagcgctt ggagaagaag aggatcaaaa agaggaaagg
901 ggagtccatg gccctcaatg agaagcagat cctcgagaag gtcaacagtc agtttgtggt
961 caacctggcc tatgcctacg agaccaagga tgcactgtgc ttggtcctga ccatcatgaa
1021 tgggggtgac ctgaagttcc acatctacaa catgggcaac cctggcttcg aggaggagcg
1081 ggccttgttt tatgcggcag agatcctctg cggcttagaa gacctccacc gtgagaacac
1141 cgtctaccga gatctgaaac ctgaaaacat cctgttagat gattatggcc acattaggat
1201 ctcagacctg ggcttggctg tgaagatccc cgagggagac ctgatccgcg gccgggtggg
1261 cactgttggc tacatggccc ccgaagtcct gaacaaccag aggtacggcc tgagccccga
1321 ctactggggc cttggctgcc tcatctatga gatgatcgag ggccagtcgc cgttccgcgg
1381 ccgtaaggag aaggtgaagc gggaggaggt ggaccgccgg gtcctggaga cggaggaggt
1441 gtactcccac aagttctccg aggaggccaa gtccatctgc aagatgctgc tcacgaaaga
1501 tgcgaagcag aggctgggct gccaggagga gggggctgca gaggtcaaga gacacccctt
1561 cttcaggaac atgaacttca agcgcttaga agccgggatg ttggaccctc ccttcgttcc
1621 agacccccgc gctgtgtact gtaaggacgt gctggacatc gagcagttct ccactgtgaa
1681 gggcgtcaat ctggaccaca cagacgacga cttctactcc aagttctcca cgggctctgt
1741 gtccatccca tggcaaaacg agatgataga aacagaatgc tttaaggagc tgaacgtgtt
1801 tggacctaat ggtaccctcc cgccagatct gaacagaaac caccctccgg aaccgcccaa
1861 gaaagggctg ctccagagac tcttcaagcg gcagcatcag aacaattcca agagttcgcc
1921 cagctccaag accagtttta accaccacat aaactcaaac catgtcagct cgaactccac
1981 cggaagcagc tagtttcggc tctggcctcc aagtccacag tggaaccagc ccagaccctt
2041 ctccttagaa gtggaagtag tggagcccct gctctggtgg ggctgccagg ggagaccccg
2101 ggagccggaa ggaggccgtc catcccgtcg acgtagaacc tcgaggtttc tcaaagaaat
2161 ttccactcag gtctgttttc cgaggcggcc ccgggcgggt ggattggatt tgtctttggt
2221 gaacattgca atagaaatcc aattggatac gacaacttgc acgtatttta atagcgtcat
2281 aactagaact gaattttgtc tttatgattt ttaaagaaaa gttttgtaaa tttctctact
2341 gtctcagttt acattttcgg tatatttgta tttaaatgaa gtgagacttt gagggtgtat
2401 attttctgtg cagccactgt taagccatgt gttccaaggc attttagcgg ggagggggtt
2461 atcaaaaaaa aaaaaaatgt gactcaagac ttccagagcc tcaaatgaga aaatgtcttt
2521 attaaatgta gaaagtgatc catacttcaa aaaaaaa
//