LOCUS HUMBETAADA 3859 bp mRNA linear HUM 15-MAY-2001
DEFINITION Homo sapiens beta-prime-adaptin (AP1B1) mRNA, complete cds.
ACCESSION L13939
VERSION L13939.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3859)
AUTHORS Peyrard,M., Fransson,I., Xie,Y.G., Han,F.Y., Ruttledge,M.H.,
Swahn,S., Collins,J.E., Dunham,I., Collins,V.P. and Dumanski,J.P.
TITLE Characterization of a new member of the human beta-adaptin gene
family from chromosome 22q12, a candidate meningioma gene
JOURNAL Hum. Mol. Genet. 3 (8), 1393-1399 (1994)
PUBMED 7987321
REFERENCE 2 (bases 1 to 3859)
AUTHORS Peyrard,M.
TITLE Direct Submission
JOURNAL Submitted (03-AUG-1994) Dept. of Molecular Medicine, Karolinska
Hospital, CMM building L8:00, Stockholm S-171 76, Sweden
REFERENCE 3 (bases 1 to 3859)
AUTHORS Peyrard,M.
TITLE Direct Submission
JOURNAL Submitted (30-DEC-1998) Dept. of Molecular Medicine, Karolinska
Hospital, CMM building L8:00, Stockholm S-171 76, Sweden
REMARK Sequence update by submitter
COMMENT On Dec 30, 1998 this sequence version replaced gi:520827.
FEATURES Location/Qualifiers
source 1..3859
/db_xref="H-InvDB:HIT000192232"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..3859
/gene="AP1B1"
/gene_synonym="BAM22"
CDS 47..2896
/gene="AP1B1"
/gene_synonym="BAM22"
/note="candidate meningioma tumor suppressor"
/codon_start=1
/product="beta-prime-adaptin"
/protein_id="AAC98702.1"
/translation="MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVG
KDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLI
RALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQG
FLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWG
QIFILDCLANYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDY
YGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYV
KLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCV
STLLDLIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIW
IVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLS
LATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICY
IGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVIPA
QGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEPEGIGGTNFVAP
PTAAVPANLGAPIGSGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTR
QVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPAAPLQVHAPLSPNQTVEISLPLS
TVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHILFVEDGKMDRQMFLATWKDIPNE
NEAQFQIRDCPLNAEAASSKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRI
QPGNPSCTDLELSLKCRAPEVSQHVYQAYETILKN"
BASE COUNT 833 a 1179 c 1120 g 727 t
ORIGIN
1 gagctattgg gacctgcgga agcctggcta cagataaggg accaaaatga ctgactcaaa
61 atatttcacc acgaccaaga aaggggagat cttcgagctg aaggcagagc tcaacagtga
121 caagaaggag aagaagaagg aggcagtgaa gaaagtgatt gcatcgatga ccgtgggcaa
181 agatgtcagt gccctcttcc ccgatgtggt caactgcatg cagacggaca acctggagct
241 gaagaagctg gtatacctct acttgatgaa ttacgccaag agtcagcctg acatggccat
301 tatggccgtc aacacctttg tgaaggactg tgaggacccc aaccccctca tccgagccct
361 ggcagtgcgg accatgggct gcatccgcgt tgacaagatc acagagtacc tgtgcgagcc
421 actccggaag tgcctgaagg acgaggatcc atatgtgcgc aagacagcag ctgtgtgcgt
481 ggccaagctc cacgacatca acgcccagct ggtggaggac cagggcttcc tggacaccct
541 taaagacctc atctccgact ctaaccccat ggtggtggcc aatgcagtgg cagcgctctc
601 agaaattgcc gagtctcacc ccagcagcaa cctgctcgat ctgaacccac agtccatcaa
661 caagctgctg acagccctca atgagtgcac cgagtggggc cagatcttca tcctggactg
721 cctcgccaac tatatgccca aggacgaccg cgaggcccag agcatctgtg agcgggtcac
781 ccccaggctc tcccatgcca actccgctgt ggtgctctct gctgtgaagg tgctgatgaa
841 gttcatggag atgttgtcta aggacttgga ctactacggc acactgctca agaagctggc
901 cccacccctg gtcacactgc tgtcagccga gccagagctg cagtatgtgg ccctgcgcaa
961 catcaatctc atcgtgcaga aaaggcctga gatcctgaag catgagatga aggtgttctt
1021 cgtgaagtac aacgacccta tctacgtgaa gctggagaag ctggacatca tgatccgcct
1081 ggcctctcag gccaacatcg cccaggtgtt ggcagagctg aaagagtacg caacagaagt
1141 ggatgtggac tttgtacgga aggctgtgcg tgctattggc cgctgcgcca tcaaggtgga
1201 gcaatctgcg gagcgctgtg tgagcacgct gctcgacctc atccagacca aggtcaacta
1261 tgtggtccag gaggccatcg tggtcatcaa ggacatcttc cgcaagtacc ccaacaagta
1321 tgagagtgtg attgccacac tgtgtgagaa tctggactcc ctggatgagc ctgaggcccg
1381 ggctgccatg atctggattg tgggcgagta cgcggaacgg atcgacaacg cagatgagct
1441 gctggagagc ttcctcgagg gcttccatga cgagagcaca caggtccagc tgcagctgct
1501 gacagccatt gtgaaactct ttctaaagaa gccaacagag acccaggagc tggtgcagca
1561 ggtcctcagt ttggccactc aggactcaga taacccagac ctgcgggacc gtggctacat
1621 ctactggcgc ctgctgtcca cggacccggt ggcagccaag gaggtggtgt tggctgagaa
1681 gccactcatc tctgaagaga cggacctcat cgagcccaca ctgttagacg agcttatctg
1741 ctacatcggc acgctggctt ccgtctacca taagcctccc agtgcctttg tggagggggg
1801 ccggggcgtc gtgcacaaga gcctgccacc tcgcacggcc tcgagtgaga gcgcagagag
1861 ccctgagaca gcccctactg gagcacctcc tggggagcag ccagatgtca tccccgccca
1921 gggcgacctg ctgggtgacc tcctcaacct ggacctcggc cccccagtga gcggcccacc
1981 cctggccacc tcctcggtgc agatgggagc tgtggacctt cttggcggtg gccttgacag
2041 cctgatgggg gatgagcctg aagggattgg gggcaccaac ttcgtggcac ctccaacagc
2101 agcagtacca gccaatcttg gagcacccat cggcagtggc ctgagtgacc tctttgacct
2161 gaccagtggc gtgggcaccc tgtcaggatc atatgtggcc cccaaagcag tctggctccc
2221 agccatgaag gctaaggggc tggagatctc aggcaccttc acccgccagg tgggctccat
2281 ctccatggac ctgcagctga ccaacaaggc cttgcaggtc atgaccgact ttgccatcca
2341 gttcaaccgc aacagctttg gcctggcccc cgccgccccc ctccaggtcc acgcgccact
2401 cagccccaac cagacagtgg agatctccct gcctctcagc acggtgggct cggtcatgaa
2461 gatggagcct ctgaacaacc tccaggtggc cgtgaagaac aacatcgatg tcttctactt
2521 cagcaccttg tacccactgc acatcctctt tgtggaggac gggaagatgg accggcagat
2581 gttcctggcc acatggaagg atattcccaa tgagaatgag gcccagttcc agatcagaga
2641 ctgccccctc aatgcagagg ctgcgagcag caagctgcag agcagcaaca tcttcactgt
2701 cgccaagagg aacgtggagg gccaggacat gctctaccag tccctgaagc tgaccaacgg
2761 catctgggtg ctggcggagc tgcggatcca gccgggcaac cccagctgca cggacttaga
2821 gctgtccctg aagtgtcgag caccagaggt gtcccagcac gtgtaccagg cctacgagac
2881 catcctcaag aactgagacc ccggccagcg cccaccccag ccttctgccc gccccatcga
2941 ggaggcccct cgggggcagc acatcttcct cctcgcagga gggaccaggc ggggctccag
3001 gccactcagt gggctccctg gtcctgatgg cagaacccac ccgatccctg gggtagggca
3061 ccaccccctc ctggggtgag agcgcagtgc actcccgtgc tctgggacac ccctgctcct
3121 gtggctgtga tgtggggtta agtgaggtgg ggaccaaagg aaacagagcc agagcagcca
3181 cagaagctgt gcctgaaggg tgagtgtgga gcttgcccct ccggctcaca gccccggcag
3241 cccctggctc cttggtctct ccggttggtg ttaaagggcc ctccactgcc acctctcatg
3301 ggatggaccc tgccaacctg gcctgggtgt gcagggaggg gttccccttg gtaccaggag
3361 agctgctcac ttagggcctg gggctcaagg agctgtaggt gccggcagag gggcagagct
3421 aggctgggag gagcccaggg cctgcaccac ccacttgcaa ccaccaggct ggtgccctgc
3481 agctgtgcca gttgggccac agcctcccga gtgctgaccc acatggtcaa gaccaggcag
3541 aagctcccag agcccctgtc tcgggctccc caccgactgg cagctgcact atccccaact
3601 ccccacttct gccccaaggg tggtcactgc ctgtgataca ttcctcagtg tcgcctctga
3661 gcccaggcct cctgccacaa agactgggcc gagagatggg gctgggtaag cgggtgcgcc
3721 tcctgtttgg gtttcttcgg ggtttctctg tagtgtctgc tgccctcctc ctggcctccc
3781 aggtttcagt tgtgtctgac agagcattag gttttcctgt tactgctgtg taataataaa
3841 gaaagattcg gcttttggc
//