LOCUS HUMAF4Y 9390 bp mRNA linear HUM 31-DEC-1994
DEFINITION Human AF-4 mRNA, complete cds.
ACCESSION L13773
VERSION L13773.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9390)
AUTHORS Nakamura,T., Alder,H., Gu,Y., Prasad,R., Canaani,O., Kamada,N.,
Gale,R.P., Lange,B., Crist,W.M., Nowell,P.C., Croce,C.M. and
Canaani,E.
TITLE Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities
in acute leukemia share sequence homology and/or common motifs
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 90 (10), 4631-4635 (1993)
PUBMED 8506309
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..9390
/db_xref="H-InvDB:HIT000192216"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/germline
gene 1..9390
/gene="AF-4"
CDS 421..4053
/gene="AF-4"
/codon_start=1
/protein_id="AAA58360.1"
/translation="MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEP
YKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSI
PSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLT
QDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQ
QTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPP
PSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAK
LTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDS
QHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP
PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPP
TTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKS
SSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGE
REPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKA
LSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLP
LPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHS
SEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPS
SQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPK
QRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAK
KMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIM
SLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVA
QAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYV
TITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQ
ELTKTP"
BASE COUNT 2609 a 2179 c 2063 g 2539 t
ORIGIN
1 ggcaatttct tttcctttct aactgtggcc cgcgttgtgc tgttgctggg caggcgttgg
61 gcgccggcgg tcttcgagcg tgggggcccg ctggctttcc cttctcagaa actgcgccgg
121 gggcgctcgc ttgccccgga ttcggacgcg gcgctccccg ggctcgtctg aagtgcagat
181 cgccgcagag gccccagtgc ccggatgtcc atcaggatta gcgcgagcca atacgggccg
241 agcccggggc tgcgccgagg acgcccgggg ctcgagagca ggtagtcccg taacatcggg
301 gcgccgcgcc gggacgcgtc cccgcccggc tccgccaaat ggtgagcgcg gcgctggcag
361 cagggcccgc ggggtgaagg cgctcatgga cggaagaccc ctggctctat aagctgaatt
421 atggcagccc agtcaagttt gtacaatgac gacagaaacc tgcttcgaat tagagagaag
481 gaaagacgca accaggaagc ccaccaagag aaagaggcat ttcctgaaaa gattcccctt
541 tttggagagc cctacaagac agcaaaaggt gatgagctgt ctagtcgaat acagaacatg
601 ttgggaaact acgaagaagt gaaggagttc cttagtacta agtctcacac tcatcgcctg
661 gatgcttctg aaaataggtt gggaaagccg aaatatcctt taattcctga caaagggagc
721 agcattccat ccagctcctt ccacactagt gtccaccacc agtccattca cactcctgcg
781 tctggaccac tttctgttgg caacattagc cacaatccaa agatggcgca gccaagaact
841 gaaccaatgc caagtctcca tgccaaaagc tgcggcccac cggacagcca gcacctgacc
901 caggatcgcc ttggtcagga ggggttcggc tctagtcatc acaagaaagg tgaccgaaga
961 gctgacggag accactgtgc ttcggtgaca gattcggctc cagagaggga gctttctccc
1021 ttaatctctt tgccttcccc agttccccct ttgtcaccta tacattccaa ccagcaaact
1081 cttccccgga cgcaaggaag cagcaaggtt catggcagca gcaataacag taaaggctat
1141 tgcccagcca aatctcccaa ggacctagca gtgaaagtcc atgataaaga gacccctcaa
1201 gacagtttgg tggcccctgc ccagccgcct tctcagacat ttccacctcc ctccctcccc
1261 tcaaaaagtg ttgcaatgca gcagaagccc acggcttatg tccggcccat ggatggtcaa
1321 gatcaggccc ctagtgaatc ccctgaactg aaaccactgc cggaggacta tcgacagcag
1381 acctttgaaa aaacagactt gaaagtgcct gccaaagcca agctcaccaa actgaagatg
1441 ccttctcagt cagttgagca gacctactcc aatgaagtcc attgtgttga agagattctg
1501 aaggaaatga cccattcatg gccgcctcct ttgacagcaa tacatacgcc tagtacagct
1561 gagccatcca agtttccttt ccctacaaag gactctcagc atgtcagttc tgtaacccaa
1621 aaccaaaaac aatatgatac atcttcaaaa actcactcaa attctcagca aggaacgtca
1681 tccatgctcg aagacgacct tcagctcagt gacagtgagg acagtgacag tgaacaaacc
1741 ccagagaagc ctccctcctc atctgcacct ccaagtgctc cacagtccct tccagaacca
1801 gtggcatcag cacattccag cagtgcagag tcagaaagca ccagtgactc agacagttcc
1861 tcagactcag agagcgagag cagttcaagt gacagcgaag aaaatgagcc cctagaaacc
1921 ccagctccgg agcctgagcc tccaacaaca aacaaatggc agctggacaa ctggctgacc
1981 aaagtcagcc agccagctgc gccaccagag ggccccagga gcacagagcc cccacggcgg
2041 cacccagaga gtaagggcag cagcgacagt gccacgagtc aggagcattc tgaatccaaa
2101 gatcctcccc ctaaaagctc cagcaaagcc ccccgggccc cacccgaagc cccccacccc
2161 ggaaagagga gctgtcagaa gtctccggca cagcaggagc ccccacaaag gcaaaccgtt
2221 ggaaccaaac aacccaaaaa acctgtcaag gcctctgccc gggcaggttc acggaccagc
2281 ctgcaggggg aaagggagcc agggcttctt ccctatggct cccgagacca gacttccaaa
2341 gacaagccca aggtgaagac gaaaggacgg ccccgggccg cagcaagcaa cgaacccaag
2401 ccagcagtgc ccccctccag tgagaagaag aagcacaaga gctccctccc tgccccctct
2461 aaggctctct caggcccaga acccgcgaag gacaatgtgg aggacaggac ccctgagcac
2521 tttgctcttg ttcccctgac tgagagccag ggcccacccc acagtggcag cggcagcagg
2581 actagtggct gccgccaagc cgtggtggtc caggaggaca gccgcaaaga cagactccca
2641 ttgcctttga gagacaccaa gctgctctca ccgctcaggg acactcctcc cccacaaagc
2701 ttgatggtga agatcaccct agacctgctc tctcggatac cccagcctcc cgggaagggg
2761 agccgccaga ggaaagcaga agataaacag ccgcccgcag ggaagaagca cagctctgag
2821 aagaggagct cagacagctc aagcaagttg gccaaaaaga gaaagggtga agcagaaaga
2881 gactgtgata acaagaaaat cagactggag aaggaaatca aatcacagtc atcttcatct
2941 tcatcctccc acaaagaatc ttctaaaaca aagccctcca ggccctcctc acagtcctca
3001 aagaaggaaa tgctcccccc gccacccgtg tcctcgtcct cccagaagcc agccaagcct
3061 gcacttaaga ggtcaaggcg ggaagcagac acctgtggcc aggaccctcc caaaagtgcc
3121 agcagtacca agagcaacca caaagactct tccattccca agcagagaag agtagagggg
3181 aagggctcca gaagctcctc ggagcacaag ggttcttccg gagatactgc aaatcctttt
3241 ccagtgcctt ctttgccaaa tggtaactct aaaccaggga agcctcaagt gaagtttgac
3301 aaacaacaag cagaccttca catgagggag gcaaaaaaga tgaagcagaa agcagagtta
3361 atgacggaca gggttggaaa ggcttttaag tacctggaag ccgtcttgtc cttcattgag
3421 tgcggaattg ccacagagtc tgaaagccag tcatccaagt cagcttactc tgtctactca
3481 gaaactgtag atctcattaa attcataatg tcattaaaat ccttctcaga tgccacagcg
3541 ccaacacaag agaaaatatt tgctgtttta tgcatgcgtt gccagtccat tttgaacatg
3601 gcgatgtttc gttgtaaaaa agacatagca ataaagtatt ctcgtactct taataaacac
3661 ttcgagagtt cttccaaagt cgcccaggca ccttctccat gcattgcaag cacaggcaca
3721 ccatcccctc tttccccaat gccttctcct gccagctccg tagggtccca gtcaagtgct
3781 ggcagtgtgg ggagcagtgg ggtggctgcc actatcagca ccccagtcac catccagaat
3841 atgacatctt cctatgtcac catcacatcc catgttctta ccgcctttga cctttgggaa
3901 caggccgagg ccctcacgag gaagaataaa gaattctttg ctcggctcag cacaaatgtg
3961 tgcaccttgg ccctcaacag cagtttggtg gacctggtgc actatacacg acagggtttt
4021 cagcagctac aagaattaac caaaacacct taatggagcc ccaggttgat tcaatgcctt
4081 gggaactatt tttgcacatt ggaagcctca aaaacagtcc agacgtttgt ttcatcagga
4141 caccaaactc taaaaaagaa gcaccacgag atggccagga catttgtcca cttaaactct
4201 caacaacagt gtgatcattg gttggacact gtggttatgc agaagcagag atgaggaggc
4261 tggccccaga gatgatcttg cccttcctaa ctaaaggaca gaagtgcaat ttagcttaaa
4321 tgggtgtatg aatggtctag aaacatttct attttttttt taaaccagca ggatacaagt
4381 tgcaaatgaa atgaggagaa acagtttcaa ctctgaaagt gaatttcacg tcatctcagt
4441 agccacgcta gtccattccc agaaggaaat tttttttttt aacaatgact tttggtaaag
4501 ggttttgtgg atgatttttt ttcttttgag ttttgggaga aatatttgtt taataacttc
4561 taatggccat ctgtaaacca taagtaatga aggactccac tgtgccccac tttctgccaa
4621 tgaacagtgg cttgataata ccaagtattg ttgtaattta taaaattgaa ggcaaccccc
4681 gctcctgccg cccccaatct ccccattgcc tagagcgctg cacattgacc ccagctctga
4741 cttctcatta ctgtgctgaa agtcagccca cgtcggagcg gtgaggagga gccacagcac
4801 atggggtgcc acctcgaggt ctgcacagga ggacttggcg ctgccatttc ctacccctgc
4861 catttcccac ccctgcttca gcgaaaggga ctctctaaca gggcagtcac tgttgactct
4921 attctgaatt tcctcccttg gggaagaagg gaaccaacat ttatacctga ccagatggct
4981 aaagtgcttt taaagttttg tttaagtaga gctggaattt gaggtgctga tctgtggtct
5041 acagttatgt ggtaactcat gttgtccagc caactcagag tttcgtcagt gaacaagaaa
5101 catgaaatct gcttcttaga gaggctatat ttttctgcta caaatatttt atatttatag
5161 caaaactaga ctttcagagt ccttgattgt ctaggggaag ttaactccct gagaggatgt
5221 agagatttgg ggtggttgat tagacttttg aaaaactcat caccacatgc cttcactcca
5281 gagtgttctc agctagattt gatttggttg aggaggaact gtggccctcc gtaagttatt
5341 gccatagtgt atgcattaaa ccaagtccat tttgaatgac ctaaaatgaa gtaacacaat
5401 cagaaatccc atgtgcccat aagcacagat ttttcttttt cattgaaact ttaaaggtta
5461 ttattggaaa cattactttg agtgcagtgt ttttaaaagc caattctttt ttatcccttt
5521 tagaagtaga atttgcacac ttactacaat tgaggagtgt catctctata actttttctc
5581 cgcctttgtc ccattctgcc cctggacatg tttcctacca agcatgtttc acattttcct
5641 attagtggag gagggagaac catatttatt tataatgaag acatctaaga tccctatgat
5701 gaatgcagga actctcttgg tagtttgtaa atacacaaag ggatgtgtcg agggatggga
5761 gcgatgctta tctctcacag tgtgagtggt ctgtgtgagg ctgttccttc agttcttctc
5821 cagactgttc tttggttgtc acttaagtca gaggtctggt ccctcatgtt taggtgaaag
5881 ccagagaatg acagctgtag tcatatctga gcataagacc ttgatgtgtg attcctgatg
5941 accggtttca tttattcatg taataaagca aaggccctgg tcctttttaa actactagtt
6001 ttaaaaacct gtgttaaatg aacagtaatt gcctggtagg tttggtgtgt gtgtagcatt
6061 gtgtgtccat ctgttatatg taaaggacaa ggcaccagaa tcaggcttta tttcgatatt
6121 gaagatgtta tttaacatct ttcttttttc cttactccct tagccatccc ctcccctttt
6181 gtcctatcat tccctagaac aagccacctg tcaattgtga agggttgtgt tctttatggc
6241 aggttctatg cagattgtgc cagagcatgt gcgtgttctg ttggcaagcc acagtgctcc
6301 cttgactgaa gacatttcca ggtagatttc tcagccagct ctaaaacaga ttgctttttc
6361 agtggcctta ctctttgtgg gttttttttt ttctctgaac ttgatataaa gattttattt
6421 gtcccttgaa aaagtaacaa atgtgcatag atcaatttgt actactttgg tcattggata
6481 tttctgatcc ttattgcatt gtacctaaag gagagtaact aatggtaacc tttttaatag
6541 agtatgtgaa aggtagtggc tgatgaatcc ttaacgttca tagggtcttt ttgctgttac
6601 ggttgtatat agaggtctga aggattttta aaatgatttg cactttttca ctgcatgctt
6661 acaattccca aaggcaaaat ctgtactgag gtagatcatt tgaaagggct agattataaa
6721 attaagcctt agagtatgga aagttcttat aacaataata gtacacactt cagagtaaga
6781 caaatgcaaa gcatcttaag gagtgaaaat agagtctaaa tcttgccttt ggcactacaa
6841 ggtgtgtgtg tgtgtgtgtg ttgtgtgtct ttagtaggaa atggaagaac actgttttat
6901 tttttaaagt gtttaatgtt tctgtccttt ctgtgaatta ttgaatttaa gagccctgct
6961 aaataatgaa aaaacacttt actaaaattt atcaaattat actgggttcg gattgtgaaa
7021 acattggcca cctagtagca gtggtgagga gtgggagggc ccagcaagca tttatcagaa
7081 atagaatcac aataggagga gaatttggct gtctgatatt atgatttgat tacaatactg
7141 aatgggaaaa gtatctaata ttttgtaaca aaaagacctt catattatct gttttgacca
7201 aaatatgtag ctatttccct tacacagatt ggaccgcact tatctccctt gtcctgtatc
7261 ctttaatttc aggtctcagg atgtttagaa agctaaaacc ccctacccct ttctggctga
7321 aaacttgcct tatttggtat cttacacatt aatgttacta gcatcaggag cttactgttt
7381 tattatgatt catcttcagt aatttttaga agcaagaaga aagccattgt gtcctctaca
7441 attaacaaaa cttatctctg atatacaaag ggatataaat atatacactt aaatagagaa
7501 aaagaggttg attgaattgt gcctttgagt gaacccagtt tttaaatacc gctgtgtttg
7561 tttcgccatg gcttcaggga tgctacatgg ctcttgcacc ttttactcct ctgctttatg
7621 aagtttgagt tgtatttgtg catcttaaag taggttgagg cttgaggctg ggctttcggg
7681 tttttttgtt ttttgttttg ttttgttttg ttttgttttc ttgtacttaa acctgcttgc
7741 ttcctaccac agattcttta ttttcccaaa cactacaaaa aaacttttaa aactttgcca
7801 tttcatctgt ttacactctt tgccactgat tagcagtatt taaatcttgc aagaatattt
7861 tgtgctttct ttagaaacac aagagtatag atttttctca ctgaaaagtg agagttacgc
7921 attgcagcca tgaagggatg ctaggatcaa ttatggcagt accttttttc ccctcctgtt
7981 cttgagccag ttgtctcttt tgttttgggt cccacttagg attaacggat gtaaggtatt
8041 ttcctgtgcc tttattttgt gtcattctat tggaaggagg tgtaacggca gaatagcatc
8101 gtgttggggg ttttccttca aacactgcaa gtgatattgc caccatgtga acctcaaata
8161 tgcaatccag ttgtgttggt ttctcggtga cttggagtgt tcatctcttc atgaattgtg
8221 agcactgacc atgttcttca gttcttaatt atggtgagtt gacaaatacc aactactgct
8281 tttctttagg tggctataaa tttcttactg tcaggaggaa atgacattat attctgttcc
8341 actgaacgtc agagatcagc aggcactgta ctgggtagag aagtgcctat acttctctac
8401 ctaagagggc aggagggaaa ccctacagct ccttgtgagc ctatatatta gtatatcggc
8461 ctggagagga caagggaata agaccactca tagtgaggct ggccaagctg cactggtcgg
8521 accaggcagt ggctgaccta aggaaggcaa cttgctttgc ttaaaagtag attttttaag
8581 caatgcttaa cacaggcagc attcaccttt gttcaggcca tcgacatgta ttgttaaaat
8641 tactgcatat ccccctcaga tatcaagtat acactgttca tgttggggtt gtgtgtgtgt
8701 atgtgtgtat gtacgcacgc atgtgtccca aatcttgttt taattttttt tttctgaatg
8761 tgatcatgtt ttggataata cctgagcagg gttgcctttt ttttatttat taccattata
8821 tattatatta tattatatat tttttgcttt cttataactt tggaggaaag tcaaatcttg
8881 gtattattaa aattgtttta aaaaggagta aattttccag ttgataaatg aaaatcactg
8941 gcctatgttt aataagtttt tctttaatta ctgtggaata acgtgccagc tatcatcaac
9001 acaatgattt tgtacatagg gtagggaagc agtgatgctc tcaatgggaa gatgtgcaac
9061 acaaattaag gggaactcca tgtattttac ctacttcagc aatggaactg caacttgggg
9121 ctttgtgaat aaaatttagc tgccttgtat agtcgtttga aagaatatgt gatctgtgag
9181 agaattatag ttttttttta gaagaaaaat ctgcaaaaga tctttccaaa gacaatgtgc
9241 cacagatctt ttgttctctg taatgaggat taattgctgt ttaaacaaaa atgtaattgt
9301 tcatctttaa attctttcct tttcataaga ggatcaagct gtaaaaaaac aaaaaaatta
9361 ataaaaattt cgagaaatca aaaaaaaaaa
//