LOCUS HUMDEOXDEA 1831 bp mRNA linear HUM 03-AUG-1993
DEFINITION Homo sapiens (clone pCD12) deoxycytidylate deaminase mRNA, complete
cds.
ACCESSION L12136
VERSION L12136.1
KEYWORDS deoxycytidylate deaminase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1831)
AUTHORS Weiner,K.X., Weiner,R.S., Maley,F. and Maley,G.F.
TITLE Primary structure of human deoxycytidylate deaminase and
overexpression of its functional protein in Escherichia coli
JOURNAL J. Biol. Chem. 268 (17), 12983-12989 (1993)
PUBMED 7685356
COMMENT Original source text: Homo sapiens (library: lambda-ZAPII) cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..1831
/db_xref="H-InvDB:HIT000192145"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
/tissue_lib="lambda-ZAPII"
CDS 1..537
/EC_number="3.5.4.12"
/function="deaminates dCMP to dUMP"
/experiment="experimental evidence, no additional details
recorded"
/note="hexamer; allosteric enzyme; nucleotide
metabolizing"
/codon_start=1
/product="deoxycytidylate deaminase"
/protein_id="AAA35755.1"
/translation="MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNS
ENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCS
MYVALFPCNECAKLIIQAGIKEVIFTSDKYHDSDEATAARLLFNMAGVTFRKFIPKCS
KIVIDFDSINSRPSQKLQ"
BASE COUNT 455 a 408 c 446 g 522 t
ORIGIN
1 atgagtgaag tttcctgcaa gaaacgggac gactatttgg aatggccaga gtattttatg
61 gctgtggcct tcttatcagc acagagaagc aaagatccaa attcccaggt cggcgcctgc
121 atcgtgaatt cagaaaacaa gattgtcggg attgggtaca atgggatgcc aaatgggtgc
181 agtgatgacg tgttgccttg gagaaggaca gcagagaata agctggacac caaatacccg
241 tacgtgtgcc atgcggagct gaatgccatc atgaacaaaa attcgaccga tgtgaaaggc
301 tgtagtatgt atgtcgcctt gttcccttgt aatgaatgcg ctaagctcat catccaggca
361 ggtataaaag aagtgatttt cacgtctgat aaataccatg atagtgacga ggcaactgct
421 gcgaggctcc tgtttaatat ggccggggtg acattccgga aattcatacc gaagtgcagc
481 aagattgtca ttgactttga ttcaattaac agcagaccga gtcaaaagct tcagtgagtt
541 acatctcatt caatctccag aagattggga ttatcgtctt ctaagaggtt gctaatgcct
601 ttcatcttga agttacacat aacttcttac tagccagtat ggcaaaagta ggcatctaaa
661 gaatataaag cctcaaatct tccttactgt ctctcttgtc acatggaatc tacatgtgtt
721 tgaactattg ctttaggatt taaaataggg gagcctgtgg tggcctggtg cacagggcta
781 gaacgagagt gcctcccctt cttgtgtcct ggctggctgg gatgctggtg gctcttcaga
841 ggagcatcag ctgtctgtca tctgctgcga tccggcagcc tctcttcact gctacatgtg
901 ctggaaggac aaataaataa ttgtggttgt gttcttaatg gggacgagca gacacactga
961 tctgaacatc tggcccaagt gaagcatggc atatagtgcc cttggaagaa aattaggcct
1021 caaatgacag tagcattgaa gtgtttgctg cagagttgag ggaaaccccc agccaccctc
1081 ccggaatccg agatagggtg gcacatctgt cctgacagac gaggagtgta actgaaccag
1141 gaatatttcc tccattcctg ctctcccact gcacacaggg tggtggcaca ttatccctct
1201 ggggggtggg gacgcctgtt gttttggctc aatttgggtt tgttggtcac atggagctct
1261 tccatttcgt ttagctgaat aatgagttgt tcctagagga gacagcctgt ctctccttgt
1321 tgcccccaaa gcccatgccc tgccgtggtg gcagctgggg ctgtggatgg gaggggtccc
1381 caacatggat gtgttgcccc tcctccgcat gccaacgcag ttcatgtaca aggcccctct
1441 gcaactggag agaaaattaa ttcctatccc gtgagtggat tgtgagaaat tccacccacg
1501 tggagacagc ttactgcagc actgttggtg ttcggagctc ttctgtgccc tggctccatg
1561 ctttcaccta cacaagcatc accttcctaa tcaccgcggg gcggggagcg tgtggctgtg
1621 ccccttctct ttaatctcat ttaattttta ttaaacatgc tcagtacctg tgttgagaaa
1681 aggctttctt tatcctaaag attattacct ttttaaagtg ctcttatatt ttcatgagtt
1741 tttattttgt ctctgagatt ttgtattcca cattctaggg tattctgtaa tttggctcct
1801 taccaatatt attaaaatct tattaaaatc t
//