LOCUS HUMPHOSPDL 2893 bp mRNA linear HUM 01-SEP-1993
DEFINITION Human phospholipase D mRNA, complete cds.
ACCESSION L11701
VERSION L11701.1
KEYWORDS phospholipase D.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2893)
AUTHORS Tsang,T.C., Fung,W.-J.C., Levine,J., Metz,C.N., Davitz,M.A.,
Burns,D.K., Huang,K.-S. and Kochan,J.P.
TITLE Isolation and expression of two human glycosylphosphatidylinositol
phospholipase D (GPI-PLD) cDNAs
JOURNAL FASEB Journal 6, 1922-1922 (1992)
REFERENCE 2 (bases 1 to 2893)
AUTHORS Tsang,T.C., Fung,W.-J.C., Metz,C.N., Davitz,M.A., Burns,D.K.,
Huang,K.-S. and Kochan,J.P.
TITLE Identification and functional chracterization of two human
glycosyl-phosphatidylinositol specific phospholipase D cDNAs
JOURNAL Unpublished
COMMENT Original source text: Homo sapiens liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2893
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
CDS 33..2558
/note="precursor"
/codon_start=1
/product="phospholipase D"
/protein_id="AAA36444.1"
/translation="MSAFRLWPGLLMIVMASLCHRGSSCGLSTHIEIGHRALEFLHLH
NGHVNYKELLLEHQDAYQAGTVFPDCFYPSLCKGGKFHDVSESTHWTPFLNASVHYIR
ENYPLPWEKDTEKLVAFLFGITSHMVADVSWHSLGIEQGFLRTMGAIDFHGSYSEAHS
AGDFGGDVLSQFEFNFNYLARRWYVPVKDLLGIYEKLYGREVITENVIVDCSHIQFLE
MYGEMLAVSKLYPSYSTKSPFLVEQFQEYFLGGLDDMAFWSTNIYHLTSFMLENGTSD
CSLPENPLFIACGGQQNHTQGSKMQKNDFHRNLTSSLTENIDRNINYTERGVFFSVNS
WTPDSMSFIYKALERNVRTMFIGGSQLSQKHISSPLASYFLSFPYARLGWAMTSADLN
QDGYGDLVVGAPGYSRPGRIHIGRVYLIYGNELGLPPVDLDLDKEAHGILEGFQPSGR
FGSALAMLDFNMDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGRMSSSPNITISCQ
DIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSNKEKLNVE
AANWTVRGEEDFAWFGYSLHGVTVDNRTLLLVGSPTWKNASRLGRLLHIRDEKKSLGR
VYGYFPPNSQSWFTIVGDKAMGKLGTSLSSGHVLMNGTLTQVLLVGAPTRDDVSKMAF
LTMTLHQGGATRMYALTSDLQPPLLSTFSGDRRFSRFGGVLHLSDLDDDGVDEIIVAA
PLRIADVTSGLIGGEDGRVYVYNGKETTLGDMTGKCKSWMTPCPEEKAQYVLISPEAS
SRFGSSLITVRSKAKNQVVIAAGRSSLGARLSGALHVYSFGSD"
sig_peptide 33..104
mat_peptide 105..2555
/product="phospholipase D"
/note="putative"
BASE COUNT 691 a 702 c 738 g 762 t
ORIGIN
1 cgtcattaga ggagccggtg gggaatgaga gcatgtctgc tttcaggttg tggcccggcc
61 tgctgatgat cgtgatggct tctctctgcc atagaggttc atcgtgtggc ctttcaacgc
121 acatagaaat cggacacaga gctctggagt ttcttcatct tcacaatggg catgttaact
181 acaaagagct gttactagaa caccaggatg catatcaggc tggaaccgtg tttcctgatt
241 gtttttaccc tagcctctgc aaaggaggaa aattccatga tgtgtctgag agcactcact
301 ggactccgtt tcttaacgca agcgttcatt atatccgaga gaactatccc cttccctggg
361 agaaggacac agagaaactg gtagctttct tgtttggaat tacttctcat atggtagcag
421 atgtcagctg gcatagtctg ggcattgaac aaggattcct taggaccatg ggagctattg
481 attttcacgg ctcctattct gaggctcatt cagctggtga ttttggagga gatgtgttga
541 gccagtttga atttaatttt aattaccttg cacgacgctg gtatgtgcca gtcaaagatc
601 tgctgggaat ttatgagaaa ctctatggtc gagaagtcat cactgaaaat gtaattgttg
661 attgttcaca tatccagttc ttagaaatgt atggtgagat gctagctgtt tccaagttat
721 atccctctta ctctacaaag tccccgtttt tggtggaaca attccaagag tattttcttg
781 gaggactgga tgatatggcg ttttggtcca ctaatattta ccatctaacg agcttcatgt
841 tggagaatgg gaccagtgac tgcagcctac ctgagaaccc tctgttcatt gcatgtggtg
901 gccagcaaaa ccacacccag ggctcgaaaa tgcagaaaaa tgattttcac agaaatttga
961 cttcatccct aactgaaaac attgacagga atataaacta taccgaaaga ggagtgttct
1021 tcagtgtaaa ttcctggacc ccggattcca tgtcctttat ctacaaggct ttggaaagga
1081 acgtaaggac aatgttcata ggtggctctc agttgtcaca gaagcacatc tctagcccct
1141 tagcatctta cttcttgtca tttccttatg caaggcttgg ctgggcaatg acctcagctg
1201 acctcaacca ggatgggtac ggcgacctcg tggtgggcgc accaggctac agccgccctg
1261 gccgcatcca catcgggcgc gtgtacctca tctacggcaa tgaactgggt ctgccgcccg
1321 ttgacctgga cctggacaag gaggcccacg ggatccttga aggtttccag ccctcaggtc
1381 ggtttggctc ggccttggct atgttggact ttaacatgga tggcgtgcct gacctggccg
1441 tgggagctcc ctcggtgggc tctgagcagc tcacctacaa aggtgctgtg tatgtctact
1501 ttggttccaa acaaggaaga atgtcttctt cccctaacat caccatctct tgccaggaca
1561 tctactgtaa cttgggctgg actctcttgg ctgcagatgt gaatggagac agtgagcccg
1621 atctggtcat tggctcccct tttgcaccag gtggagggaa gcagaaggga attgtggctg
1681 cgttttattc tggccccagc ctgagcaaca aagagaaact gaacgtggag gcggccaact
1741 ggacggtgag aggcgaggaa gactttgcct ggtttggata ctcccttcac ggtgtcactg
1801 tggacaacag aaccttgctg ctggttggga gcccgacctg gaagaatgcc agcaggctgg
1861 gccgtttgtt acacatccga gatgagaaaa agagccttgg gagggtgtat ggctacttcc
1921 caccaaacag ccaaagctgg tttaccattg ttggagacaa ggcaatgggg aaactgggta
1981 cttccctgtc cagtggccac gtgctgatga atggaactct gacccaggtg ctgctggtgg
2041 gagccccgac acgtgatgat gtgtctaaga tggcattcct gaccatgacc ctgcaccaag
2101 gcggagccac tcggatgtac gcgctcacat ccgacctgca gccaccgctg ctcagcacct
2161 tcagcggaga ccgccgcttc tctcgatttg gtggcgttct gcacttgagt gacctggatg
2221 atgatggcgt agatgaaatc atcgtggcag cccccctgag gatagcagat gtaacctctg
2281 ggctgattgg gggagaagat ggccgagttt atgtatataa tggcaaagag accacccttg
2341 gtgacatgac tggcaaatgc aaatcgtgga tgactccatg tccagaagaa aaggcccaat
2401 atgtattgat ttctcctgaa gccagctcaa ggtttgggag ctccctgatc accgtgaggt
2461 ccaaggcaaa gaatcaagtc gtcattgccg ctggaaggag ctctttggga gcccgactct
2521 ccggggcact tcacgtctat agctttggct cagattgaag atttcactgc gtttccccac
2581 tctgcccacc tctctcatgc tgaatcacat ccatggtgag cattttgatg gacaaaatgg
2641 cacatccagt ggagctgtgg cagatcctaa tagatgtggg gctcctggga gtagagacac
2701 acaccaacag ccaccctttc tggaaatctg atatagtata tatatgactg caccaggagt
2761 atgtgaaata tcagacacac tctgctcatt catgtctcct tccacagttt atttcctcgc
2821 ttcctttgca tctaaacctt tcttctttcc gaactttttg cctatagtca gacctgctgt
2881 accacctatt tcc
//