LOCUS HUMKRUPZN 3839 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human Kruppel related zinc finger protein (HTF10) mRNA, complete
cds.
ACCESSION L11672
VERSION L11672.1
KEYWORDS KRAB protein domain; Krueppel-related protein; gene cluster;
transcription factor; zinc finger protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Bellefroid,E.J., Poncelet,D.A., Lecocq,P.J., Revelant,O. and
Martial,J.A.
TITLE The evolutionarily conserved Kruppel-associated box domain defines
a subfamily of eukaryotic multifingered proteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (9), 3608-3612 (1991)
PUBMED 2023909
REFERENCE 2 (bases 1 to 3839)
AUTHORS Bellefroid,E.J., Marine,J.-C., Ried,T., Lecocq,P.J., Riviere,M.,
Amemiya,C.T., Poncelet,D.A., Coulie,P.G., de Jong,P.J., Szpirer,C.,
Ward,D.C. and Martial,J.A.
TITLE Clustered organization of homologous KRAB zinc-finger genes with
enhanced expression in human T lymphoid cells
JOURNAL EMBO J. 12 (4), 1363-1374 (1993)
PUBMED 8467795
COMMENT Original source text: Homo sapiens (tissue library: Lambda gt10)
teratocarcinoma cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3839
/db_xref="H-InvDB:HIT000192075"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19p12-p13.1"
/cell_line="Nt2D1"
/cell_type="T lymphoid"
/tissue_type="teratocarcinoma"
/tissue_lib="Lambda gt10"
gene 1..3839
/gene="HTF10"
CDS 95..3670
/gene="HTF10"
/standard_name="ZNF91"
/note="Kruppel related; from KRAB family"
/codon_start=1
/product="zinc finger protein"
/protein_id="AAA59469.1"
/translation="MPGTPGSLEMGLLTFRDVAIEFSPEEWQCLDTAQQNLYRNVMLE
NYRNLAFLGIALSKPDLITYLEQGKEPWNMKQHEMVDEPTGICPHFPQDFWPEQSMED
SFQKVLLRKYEKCGHENLQLRKGCKSVDECKVHKEGYNKLNQCLTTAQSKVFQCGKYL
KVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKT
FHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFL
WSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSHS
SALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKTFKRLST
LTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLT
KHKRFHTREKPFKCKECGKGFIWSSTLTRHKRIHTGEKPYKCEECGKAFRQSSTLTKH
KIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTTHKI
IHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIH
TGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTE
EKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEK
PYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPY
KCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKC
EECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKPYKCEE
CGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECG
KAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKA
FNRSSKLTTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFS
QSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKPYKCEKCCKAFNQS
SILTNHKKIHTITPVIPLLWEAEAGGSRGQEMETILANTVKPLLY"
BASE COUNT 1419 a 767 c 732 g 921 t
ORIGIN
1 caggtctcga cttcactgct ctgtgtcctc tgctccagga ggcccagcct gtgtggccct
61 gtgacctgca ggtattggaa gagccacagc taagatgcca ggaacccctg gaagcctaga
121 aatgggactg ttgacattta gggatgtggc catagaattc tctccggagg agtggcaatg
181 tctggacact gcacagcaga atttatatag gaatgtgatg ttagagaact acagaaacct
241 ggccttcctg ggtattgctc tctctaagcc agacctgatt acttatctgg agcaaggaaa
301 agagccctgg aatatgaagc aacatgagat ggtggatgaa cccacaggta tatgtcctca
361 ttttcctcaa gacttttggc cagagcagag catggaagat tcttttcaaa aagtattact
421 gagaaaatat gaaaaatgtg gacatgagaa tttacagtta agaaaaggtt gtaaaagtgt
481 ggatgagtgt aaggtgcaca aagaaggtta taataaactt aaccagtgtc tcacaactgc
541 ccagagcaaa gtatttcaat gtgggaaata tttgaaagtc ttctataaat ttttaaattc
601 aaacagacat acgataagac ataccggaaa gaaatgcttc aaatgtaaaa aatgtgtcaa
661 gtcattttgc atccgtttac acaaaaccca acataaatgc gtttatatta cagagaagtc
721 ctgtaaatgt aaagaatgtg aaaaaacctt tcattggtcc tcaaccctta ctaatcataa
781 ggaaattcat actgaagata aaccctacaa atgtgaagaa tgtggcaaag cttttaagca
841 gctctcaacc cttactacac ataaaataat ctgtgctaaa gagaaaatct acaagtgtga
901 agaatgtggc aaagcatttc tatggtcctc aaccctaact agacataaga ggatacacac
961 tggagagaaa ccctacaaat gtgaagaatg tggcaaagct tttagccatt cttcaaccct
1021 tgctaaacat aagagaattc atactggaga gaaaccctac aaatgtgaag aatgtggcaa
1081 agcttttagc cattcttcag cccttgctaa acataagaga attcatactg gagagaaacc
1141 ctacaaatgt aaagaatgtg gcaaagcttt tagcaattcc tcaacccttg ctaatcataa
1201 gataactcat actgaagaga aaccctacaa atgtaaagaa tgtgacaaaa cttttaagcg
1261 actctcaacc cttactaaac ataaaataat acatgctgga gagaaactct acaaatgtga
1321 agaatgtggc aaagctttta atcgatcttc aaatcttact atacataagt ttattcatac
1381 tggagagaaa ccttacaagt gtgaagaatg tggcaaagca tttaactggt cctcaagcct
1441 tactaaacat aaaagatttc atactagaga gaaacccttc aaatgtaaag aatgtggcaa
1501 aggatttata tggtcttcaa ccctaactag acataagagg atacacactg gagagaagcc
1561 ctacaaatgt gaagaatgtg gcaaagcttt taggcaatcc tcaaccctta ctaaacataa
1621 gataattcat actggagaga aaccctacaa atttgaagaa tgtggcaaag cttttagaca
1681 atccttaacc cttaataaac ataagataat tcatagtaga gagaaaccct acaaatgtaa
1741 agaatgtggc aaagctttta agcaattctc aacccttact acacataaaa taattcatgc
1801 tggaaagaaa ctctacaaat gtgaagaatg tggcaaagct tttaatcatt cctcaagtct
1861 ttctacacat aagataattc atactggaga gaagtcttac aagtgtgaag aatgtggcaa
1921 agcatttcta tggtcctcaa ccctaagaag acataagagg atacacactg gagagaaacc
1981 ctacaaatgt gaagaatgtg gcaaagcttt tagccattct tcagcccttg ctaaacataa
2041 gagaattcat actggagaga aaccctacaa atgtaaagaa tgtggcaaag cttttagcaa
2101 ttcctcaacc cttgctaatc ataagataac tcatactgaa gagaaaccct acaaatgtaa
2161 agaatgtgac aaaactttta agcgactctc aacccttact aaacataaaa taatacatgc
2221 tggagagaaa ctctacaaat gtgaagaatg tggcaaagct tttaatcgat cttcaaatct
2281 tactatacat aagtttattc atactggaga gaaaccttac aagtgtgaag aatgtggcaa
2341 agcatttaac tggtcctcaa gccttactaa acataaaaga attcatacta gagagaaacc
2401 cttcaaatgt aaagaatgtg gcaaagcatt tatatggtct tcaaccctaa ctagacataa
2461 gaggatacac actggagaga agccctacaa atgtgaagaa tgtggcaaag cttttagccg
2521 ttcctcaacc cttactaagc ataagacaat tcatactgga gagaaaccct acaaatgtaa
2581 agaatgtggc aaagctttta agcactcctc agcccttgct aaacataaaa taatacatgc
2641 tggagagaaa ctctacaaat gtgaggaatg tggcaaagct tttaatcaat cttcaaatct
2701 tacgacacat aagataattc atactaaaga gaaaccttcc aagagtgaag aatgtgacaa
2761 agcatttatc tggtcctcaa cccttactga acataagaga attcatacca gagagaaacc
2821 ctacaaatgt gaagaatgtg gcaaagcatt tagccagcct tcacacctta ctacacataa
2881 gaggatgcac actggagaga aaccctacaa atgtgaagaa tgtggcaaag cttttagcca
2941 atcctcaacc cttactacac ataagataat tcatactgga gagaaaccct acaaatgtga
3001 agaatgtggc aaagctttta ggaaatcttc aactcttact gaacataaga taattcatac
3061 tggagagaaa ccctacaaat gtgaagaatg tggcaaagca tttagccaat cctcaaccct
3121 aactagacat acgaggatgc acactggaga gaaaccatac aaatgtgaag aatgtgggaa
3181 agcttttaat cgatcctcaa agcttactac acataagata attcatactg gagagaaacc
3241 ttacaagtgt gaagaatgtg gcaaagcatt tatatcatcc tcaaccctaa atggacataa
3301 gagaattcat actagagaga aaccctacaa atgtgaagaa tgtggcaaag catttagcca
3361 atcttcaacc ctaactagac ataagaggtt gcacaccgga gagaaaccct acaaatgtgg
3421 agaatgtggc aaagccttta aagagtcctc agctcttact aaacataaga taattcacac
3481 tggagagaaa ccctacaaat gtgaaaaatg ttgcaaagcc tttaaccagt cttcaatcct
3541 tactaaccat aagaaaattc atactatcac acctgtaatc ccactacttt gggaggccga
3601 ggcgggcgga tcacgaggtc aggagatgga gaccatcctg gctaacacag tgaaacccct
3661 tctctactaa aaaatacaaa aaactagccg ggcgtggtgg cgggcgcctg tagtcccagc
3721 tatgcgagag gctgaggcag gagaatggcg tgaacccggg aggcggagct tgcagtgagc
3781 cgagatcacg ccactgcact caagcctggg cgacagagcg agactccgtc tcaaaaaaa
//