LOCUS HUMGLYCOPR 3533 bp mRNA linear HUM 26-OCT-1993
DEFINITION Homo sapiens platelet membrane glycoprotein V mRNA, complete cds.
ACCESSION L11238
VERSION L11238.1
KEYWORDS adhesive glycoprotein; leucine-rich glycoprotein; platelet membrane
glycoprotein V.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3533)
AUTHORS Hickey,M.J., Hagen,F.S., Yagi,M. and Roth,G.J.
TITLE Human platelet glycoprotein V: characterization of the polypeptide
and the related Ib-V-IX receptor system of adhesive, leucine-rich
glycoproteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 90 (18), 8327-8331 (1993)
PUBMED 7690959
COMMENT Original source text: Homo sapiens (library: Stratagene 944201)
lung cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3533
/db_xref="H-InvDB:HIT000192048"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="WI38"
/cell_type="fibroblast"
/tissue_type="lung"
/tissue_lib="Stratagene 944201"
CDS 73..1755
/note="putative"
/codon_start=1
/product="platelet membrane glycoprotein V"
/protein_id="AAA03069.1"
/translation="MLRGTLLCAVLGLLRAQPFPCPPACKCVFRDAAQCSGGDVARIS
ALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKT
LRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDF
LPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLG
ALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFEN
PLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGA
FQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESV
QLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPR
CAGPGAHAGLPLWALPGGDAECPGPRGPPPRPAADSSSEAPVHPALAPNSSEPWVWAQ
PVTTGKGQDHSPFWGFYFLLLAVQAMITVIIVFAMIKIGQLFRKLIRERALG"
sig_peptide 73..120
mat_peptide 121..1752
/product="platelet membrane glycoprotein V"
/function="thrombin substrate"
/note="putative"
repeat_region complement(2318..2612)
/note="putative"
/rpt_family="Alu"
regulatory 3270..3275
/regulatory_class="polyA_signal_sequence"
BASE COUNT 661 a 1055 c 927 g 890 t
ORIGIN
1 ggatcccagg gttcagtaca ggcgcgaacg ctcctgtgtg ttgaccacac tcccacggtt
61 gctttttcag acatgctgag ggggactcta ctgtgcgcgg tgctcgggct tctgcgcgcc
121 cagcccttcc cctgtccgcc agcttgcaag tgtgtcttcc gggacgccgc gcagtgctcg
181 gggggcgacg tggcgcgcat ctccgcgctg ggcctgccca ccaacctcac gcacatcctg
241 ctcttcggaa tgggccgcgg cgtcctgcag agccagagct tcagcggcat gaccgtcctg
301 cagcgcctca tgatctccga cagccacatt tccgccgttg cccccggcac cttcagtgac
361 ctgataaaac tgaaaaccct gaggctgtcg cgcaacaaaa tcacgcatct tccaggtgcg
421 ctgctggata agatggtgct cctggagcag ttgtttttgg accacaatgc gctaaggggc
481 attgaccaaa acatgtttca gaaactggtt aacctgcagg agctcgctct gaaccagaat
541 cagctcgatt tccttcctgc cagtctcttc acgaatctgg agaacctgaa gttgttggat
601 ttatcgggaa acaacctgac ccacctgccc aaggggttgc ttggagcaca ggctaagctc
661 gagagacttc tgctccactc gaaccgcctt gtgtctctgg attcggggct gttgaacagc
721 ctgggcgccc tgacggagct gcagttccac cgaaatcaca tccgttccat cgcacccggg
781 gccttcgacc ggctcccaaa cctcagttct ttgacgcttt cgagaaacca ccttgcgttt
841 ctcccctctg cgctctttct tcattcgcac aatctgactc tgttgactct gttcgagaac
901 ccgctggcag agctcccggg ggtgctcttc ggggagatgg ggggcctgca ggagctgtgg
961 ctgaaccgca cccagctgcg caccctgccc gccgccgcct tccgcaacct gagccgcctg
1021 cggtacttag gggtgactct gagcccgcgg ctgagcgcgc ttccgcaggg cgccttccag
1081 ggccttggcg agctccaggt gctcgccctg cactccaacg gcctgaccgc cctccccgac
1141 ggcttgctgc gcggcctcgg caagctgcgc caggtgtccc tgcgccgcaa caggctgcgc
1201 gccctgcccc gtgccctctt ccgcaatctc agcagcctgg agagcgtcca gctcgaccac
1261 aaccagctgg agaccctgcc tggcgacgtg tttggggctc tgccccggct gacggaggtc
1321 ctgttggggc acaactcctg gcgctgcgac tgtggcctgg ggcccttcct ggggtggctg
1381 cggcagcacc taggcctcgt gggcggggaa gagcccccac ggtgcgcagg ccctggggcg
1441 cacgccggcc tgccgctctg ggccctgccg gggggtgacg cggagtgccc gggcccccgg
1501 ggcccgcctc cccgccccgc tgcggacagc tcctcggaag cccctgtcca cccagccttg
1561 gctcccaaca gctcagaacc ctgggtgtgg gcccagccgg tgaccacggg caaaggtcaa
1621 gatcatagtc cgttctgggg gttttatttt ctgcttttag ctgttcaggc catgatcacc
1681 gtgatcatcg tgtttgctat gattaaaatt ggccaactct ttcgaaaatt aatcagagag
1741 agagcccttg ggtaaaccaa tgggaaaatc ttctaattac ttagaacctg accagatgtg
1801 gctcggaggg gaatccagac ccgctgctgt cttgctctcc ctcccctccc cactcctcct
1861 ctcttcttcc tcttctctct cactgccacg ccttcctttc cctcctcctc cccctctccg
1921 ctctgtgctc ttcattctca caggcccgca acccctcctc tctgtgtccc ccgcccgttc
1981 ctggaaactg agcttgacgt ttgtaaactg tggttgcctg ccttccccag ctcccacgcg
2041 ggtgtgcgct gacactgccg ggggcgctgg actgtgttgg acccatccgt gctccgctgt
2101 gcctggcttg gcgtctggtg gagagagggg cctcttcagt gtctactgag taaggggaca
2161 gctccaggcc ggggcctgtc tcctgcacag agtaagccgg taaatgtttg tgaaatcaat
2221 gcgtggataa aggaactcat gccatccaag tgatgatggc ttttcctgga gggaaaggat
2281 aggctgttgc tctatctaat tttttgtttt tgtttttgga cagtctagct ctgtggccca
2341 ggctggcgtg cagtgggccg tctcagttca ctgcagcctc cgcctcccag gttcaagtga
2401 ttctcatgcc tcagcgttct gagtagctgg gattagaggc gtgtgccact acacccggct
2461 aatttttgta ctttttaaag tagagacggg gctttgccat attggcctgg ctgatctcaa
2521 actcctggtc ttgaactcct ggccacaagt gatctgcccg ccttggcctc ccaaagtgct
2581 gggattacag gcgtaagcca ctacacctgg ccctcttcat cgaattttat ttgagaagta
2641 gagctcttgc cattttttcc cttgctccat ttttctcact ttatgtctct ctgacctatg
2701 ggctacttgg gagagcactg gactccattc atgcatgagc attttcagga taagcgactt
2761 ctgtgaggct gagagaggaa gaaaacacgg agccttccct ccaggtgccc agtgtaggtc
2821 cagcgtgttt cctgagcctc ctgtgagttt ccacttgctt tacatccatg caacatgtca
2881 ttttgaaact ggattgattt gcatttcctg gaactctgcc acctcatttc acaagcattt
2941 atggagcagt taacatgtga ctggtattca tgaatataat gataagcttg attctagttc
3001 agctgctgtc acagtctcat ttgttcttcc aactgaaagc cgtaaaacct ttgttgcttt
3061 aattgaatgt ctgtgcttat gagaggcagt ggttaaaaca ggggctggcg agttgacaac
3121 tgtgggttca aatcccagct ctaccactta ctaactgcat gggactttgg gtaagacacc
3181 tgcttacatt ctctaagcct tggtttcctg aaccttaaaa caggataaca tagtacctgc
3241 ttcgtagagt ttttgtgaga attaaaggca ataaagcata taatgactta gcccagcggc
3301 ctgcaggcaa tacatgttaa tgaatgttag ctattattac taaaggatga gcaattatta
3361 ttggcatcat gatttctaaa gaagagcttt gagttggtat ttttctctgt gtataagggt
3421 aagtccgaac tttctcagac tggaggttac attcacatca gtctgtcttc cctgcggatg
3481 gcctcagccc tgggtggcca gactctgtgc tcacaatcca gagcaatgga tcc
//