LOCUS HUMFTA 1644 bp mRNA linear HUM 30-JAN-1996
DEFINITION Human farnesyltransferase alpha-subunit mRNA, complete cds.
ACCESSION L10413
VERSION L10413.1
KEYWORDS farnesyl-protein transferase alpha-subunit; farnesyltransferase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1644)
AUTHORS Andres,D.A., Milatovich,A., Ozcelik,T., Wenzlau,J.M., Brown,M.S.,
Goldstein,J.L. and Francke,U.
TITLE cDNA cloning of the two subunits of human CAAX farnesyltransferase
and chromosomal mapping of FNTA and FNTB loci and related sequences
JOURNAL Genomics 18 (1), 105-112 (1993)
PUBMED 8276393
COMMENT Original source text: Homo sapiens (human).
FEATURES Location/Qualifiers
source 1..1644
/db_xref="H-InvDB:HIT000192032"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="8p22-q11"
/tissue_type="retina"
CDS 7..1146
/codon_start=1
/product="farnesyl-protein transferase alpha-subunit"
/protein_id="AAA86285.1"
/translation="MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAG
EAVASPMDDGFVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDY
FRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIE
EQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDN
ELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESA
WNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDIL
NKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTENDSPTNVQQ"
BASE COUNT 497 a 338 c 388 g 421 t
ORIGIN
1 ggcgagatgg cggccaccga gggggtcggg gaggctgcgc aagggggcga gcccgggcag
61 ccggcgcaac ccccgcccca gccgcaccca ccgccgcccc agcagcagca caaggaagag
121 atggcggccg aggctgggga agccgtggcg tcccccatgg acgacgggtt tgtgagcctg
181 gactcgccct cctatgtcct gtacagggac agagcagaat gggctgatat agatccggtg
241 ccgcagaatg atggccccaa tcccgtggtc cagatcattt atagtgacaa atttagagat
301 gtttatgatt acttccgagc tgtcctgcag cgtgatgaaa gaagtgaacg agcttttaag
361 ctaacccggg atgctattga gttaaatgca gccaattata cagtgtggca tttccggaga
421 gttcttttga agtcacttca gaaggatcta catgaggaaa tgaactacat cactgcaata
481 attgaggagc agcccaaaaa ctatcaagtt tggcatcata ggcgagtatt agtggaatgg
541 ctaagagatc catctcagga gcttgaattt attgctgata ttcttaatca ggatgcaaag
601 aattatcatg cctggcagca tcgacaatgg gttattcagg aatttaaact ttgggataat
661 gagctgcagt atgtggacca acttctgaaa gaggatgtga gaaataactc tgtctggaac
721 caaagatact tcgttatttc taacaccact ggctacaatg atcgtgctgt attggagaga
781 gaagtccaat acactctgga aatgattaaa ctagtaccac ataatgaaag tgcatggaac
841 tatttgaaag ggattttgca ggatcgtggt ctttccaaat atcctaatct gttaaatcaa
901 ttacttgatt tacaaccaag tcatagttcc ccctacctaa ttgcctttct tgtggatatc
961 tatgaagaca tgctagaaaa tcagtgtgac aataaggaag acattcttaa taaagcatta
1021 gagttatgtg aaatcctagc taaagaaaag gacactataa gaaaggaata ttggagatac
1081 attggaagat cccttcaaag caaacacagc acagaaaatg actcaccaac aaatgtacag
1141 caataacacc atccagaaga acttgatgga atgcttttat tttttattaa gggaccctgc
1201 aggagtttca cacgagagtg gtccttccct ttgcctgtgg tgtaaaagtg catcacacag
1261 gtattgcttt ttaacaagaa ctgatgctcc ttgggtgctg ctgctactca gactagctct
1321 aagtaatgtg attcttctaa agcaaagtca ttggatggga ggaggaagaa aaagtcccat
1381 aaaggaactt ttgtagtctt atcaacatat aatctaatcc cttagcatca gctcctccct
1441 cagtggtaca tgcgtcaaga tttgtagcag taataactgc aggtcacttg tatgtaatgg
1501 atgtgaggta gccgaagttt ggttcagtaa gcagggaata cagtcgttcc atcagagctg
1561 gtctgcacac tcacattatc ttgctatcac tgtaaccaac taatgccaaa agaacggttt
1621 tgtaataaaa ttatagctgt atct
//