LOCUS HUMCD30 1906 bp mRNA linear HUM 23-AUG-1995
DEFINITION Homo sapiens CD30 ligand mRNA, complete cds.
ACCESSION L09753
VERSION L09753.1
KEYWORDS CD30 ligand; transmembrane protein type II.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1906)
AUTHORS Smith,C.A., Gruss,H.J., Davis,T., Anderson,D., Farrah,T., Baker,E.,
Sutherland,G.R., Brannan,C.I., Copeland,N.G., Jenkins,N.A.,
Grabstein,K.H., Gliniak,B., McAlister,I.B., Fanslow,W.,
Alderson,M., Falk,B., Gimpel,S., Gillis,S., Din,W.S., Goodwin, R.G.
and Armitage,R.J.
TITLE CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose
ligand defines an emerging family of cytokines with homology to TNF
JOURNAL Cell 73 (7), 1349-1360 (1993)
PUBMED 8391931
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1906
/db_xref="H-InvDB:HIT000191985"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="9q32"
/cell_line="con A induced PBL"
gene 1..1906
/gene="CD30"
5'UTR 1..114
/gene="CD30"
/note="G00-131-547"
CDS 115..819
/gene="CD30"
/note="homology to TNF and CD40 ligand; potential
glycosylation sites (81,109,153,189,201)"
/codon_start=1
/product="CD30 ligand"
/protein_id="AAA74594.1"
/db_xref="GDB:G00-131-547"
/translation="MDPGLQQALNGMAPPGDTAMHVPAGSVASHLGTTSRSYFYLTTA
TLALCLVFTVATIMVLVVQRTDSIPNSPDNVPLKGGNCSEDLLCILKRAPFKKSWAYL
QVAKHLNKTKLSWNKDGILHGVRYQDGNLVIQFPGLYFIICQLQFLVQCPNNSVDLKL
ELLINKHIKKQALVTVCESGMQTKHVYQNLSQFLLDYLQVNTTISVNVDTFQYIDTST
FPLENVLSIFLYSNSD"
3'UTR 817..1906
/gene="CD30"
/note="G00-131-547"
BASE COUNT 559 a 447 c 438 g 462 t
ORIGIN
1 ccaagtcaca tgattcagga ttcaggggga gaatccttct tggaacagag atgggcccag
61 aactgaatca gatgaagaga gataaggtgt gatgtgggga agactatata aagaatggac
121 ccagggctgc agcaagcact caacggaatg gcccctcctg gagacacagc catgcatgtg
181 ccggcgggct ccgtggccag ccacctgggg accacgagcc gcagctattt ctatttgacc
241 acagccactc tggctctgtg ccttgtcttc acggtggcca ctattatggt gttggtcgtt
301 cagaggacgg actccattcc caactcacct gacaacgtcc ccctcaaagg aggaaattgc
361 tcagaagacc tcttatgtat cctgaaaaga gctccattca agaagtcatg ggcctacctc
421 caagtggcaa agcatctaaa caaaaccaag ttgtcttgga acaaagatgg cattctccat
481 ggagtcagat atcaggatgg gaatctggtg atccaattcc ctggtttgta cttcatcatt
541 tgccaactgc agtttcttgt acaatgccca aataattctg tcgatctgaa gttggagctt
601 ctcatcaaca agcatatcaa aaaacaggcc ctggtgacag tgtgtgagtc tggaatgcaa
661 acgaaacacg tataccagaa tctctctcaa ttcttgctgg attacctgca ggtcaacacc
721 accatatcag tcaatgtgga tacattccag tacatagata caagcacctt tcctcttgag
781 aatgtgttgt ccatcttctt atacagtaat tcagactgaa cagtttctct tggccttcag
841 gaagaaagcg cctctctacc atacagtatt tcatccctcc aaacacttgg gcaaaaagaa
901 aactttagac caagacaaac tacacagggt attaaatagt atacttctcc ttctgtctct
961 tggaaagata cagctccagg gttaaaaaga gagtttttag tgaagtatct ttcagatagc
1021 aggcagggaa gcaatgtagt gtggtgggca gagccccaca cagaatcaga agggatgaat
1081 ggatgtccca gcccaaccac taattcactg tatggtcttg atctatttct tctgttttga
1141 gagcctccag ttaaaatggg gcttcagtac cagagcagct agcaactctg ccctaatggg
1201 aaatgaaggg gagctgggtg tgagtgttta cactgtgccc ttcacgggat acttctttta
1261 tctgcagatg gcctaatgct tagttgtcca agtcgcgatc aaggactctc tcacacagga
1321 aacttcccta tactggcaga tacacttgtg actgaaccat gcccagttta tgcctgtctg
1381 actgtcactc tggcactagg aggctgatct tgtactccat atgaccccac ccctaggaac
1441 ccccagggaa aaccaggctc ggacagcccc ctgttcctga gatggaaagc acaaatttaa
1501 tacaccacca caatggaaaa caagttcaaa gacttttact tacagatcct ggacagaaag
1561 ggcataatga gtctgaaggg cagtcctcct tctccaggtt acatgaggca ggaataagaa
1621 gtcagacaga gacagcaaga cagttaacaa cgtaggtaaa gaaatagggt gtggtcactc
1681 tcaattcact ggcaaatgcc tgaatggtct gtctgaagga agcaacagag aagtggggaa
1741 tccagtctgc taggcaggaa agatgcctct aagttcttgt ctctggccag aggtgtggta
1801 tagaaccaga aacccatatc aagggtgact aagcccggct tccggtatga gaaattaaac
1861 ttgtatacaa aatggttgcc aaggcaacat aaaattataa gaattc
//