LOCUS HUMPORIN 1464 bp mRNA linear HUM 08-JAN-1995
DEFINITION Homo sapiens porin (por) mRNA, complete cds and truncated cds.
ACCESSION L08666
VERSION L08666.1
KEYWORDS VDAC; mitochondria; porin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1464)
AUTHORS Ha,H., Hajek,P., Bedwell,D.M. and Burrows,P.D.
TITLE A mitochondrial porin cDNA predicts the existence of multiple human
porins
JOURNAL J. Biol. Chem. 268 (16), 12143-12149 (1993)
PUBMED 7685033
COMMENT Original source text: Homo sapiens blood cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1464
/db_xref="H-InvDB:HIT000191919"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="B-lymphocyte"
/tissue_type="blood"
/germline
gene 1..1464
/gene="por"
5'UTR 1..247
/gene="por"
CDS 248..1291
/gene="por"
/function="mitochondrial pore-forming protein"
/standard_name="VDAC"
/experiment="experimental evidence, no additional details
recorded"
/note="Met at bp 326 also used as initiation codon in
vitro"
/codon_start=1
/product="porin"
/protein_id="AAA60144.1"
/translation="MSWCNELRLPALKQHSIGRGLESHITMCIPPSYADLGKAARDIF
NKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWN
TDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFA
GPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGG
SIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQT
LRPGVKLTLSALVDGKSINAGGHKVGSPWSWRLNPAERNLWEWISEDLALIYFHCDQQ
QAFFPPEDDQNKG"
CDS 326..1291
/gene="por"
/experiment="experimental evidence, no additional details
recorded"
/note="Met at bp 248 also used as initiation codon in
vitro"
/codon_start=1
/product="porin"
/protein_id="AAA60145.1"
/translation="MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTS
GSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTT
FSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSA
KSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTR
FGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVG
SPWSWRLNPAERNLWEWISEDLALIYFHCDQQQAFFPPEDDQNKG"
3'UTR 1292..1464
/gene="por"
polyA_site 1464
/gene="por"
BASE COUNT 397 a 315 c 356 g 396 t
ORIGIN
1 gctgctggag ctgcagcccg accgcgagcg tgccaagcgg cttcagcagc tagcggacgt
61 ggcggcggcc cccctcagga caccaccaga ttcccctctt cccgcggcct cgccatggcg
121 acccacggac agacttgcgc gcgtcgatcg gatcaatcac ttttctagag gaagtagcag
181 tccctcttgt gagagcgcaa ggtcattact tgtgctccta agggcgtgga cgtgctttgt
241 ggaatgaatg agctggtgta atgagctcag attgcctgcc cttaagcagc acagcattgg
301 ccgaggactt gagagtcaca ttacaatgtg tattcctcca tcatatgctg accttggcaa
361 agctgccaga gatattttca acaaaggatt tggttttggg ttggtgaaac tggatgtgaa
421 aacaaagtct tgcagtggcg tggaattttc aacgtccggt tcatctaata cagacactgg
481 taaagttact gggaccttgg agaccaaata caagtggtgt gagtatggtc tgactttcac
541 agaaaagtgg aacactgata acactctggg aacagaaatc gcaattgaag accagatttg
601 tcaaggtttg aaactgacat ttgatactac cttctcacca aacacaggaa agaaaagtgg
661 taaaatcaag tcttcttaca agagggagtg tataaacctt ggttgtgatg ttgactttga
721 ttttgctgga cctgcaatcc atggttcagc tgtctttggt tatgagggct ggcttgctgg
781 ctaccagatg acctttgaca gtgccaaatc aaagctgaca aggaataact ttgcagtggg
841 ctacaggact ggggacttcc agctacacac taatgtcaat gatgggacag aatttggagg
901 atcaatttat cagaaagttt gtgaagatct tgacacttca gtaaaccttg cttggacatc
961 aggtaccaac tgcactcgtt ttggcattgc agctaaatat cagttggatc ccactgcttc
1021 catttctgca aaagtcaaca actctagctt aattggagta ggctatactc agactctgag
1081 gcctggtgtg aagcttacac tctctgctct ggtagatggg aagagcatta atgctggagg
1141 ccacaaggtt ggctcgccct ggagttggag gcttaatcca gctgaaagaa acctttggga
1201 atggatatca gaagatttgg ccttaatata tttccattgt gaccagcagc aggctttttt
1261 ccccccagaa gatgatcaaa acaaaggatg atctcaacaa gagctgtatt ttaagtattt
1321 agacagttct ttgttagctg gtttctagtt ggttatctag ttaccaatgc tgcagtcctg
1381 cagtcaccta tacattattt aaatgtattt aactgttaaa tgcgctaccc accaataatg
1441 aaatagacct ttatgaaaac tgtg
//