LOCUS HUMDYNA 3187 bp mRNA linear HUM 08-SEP-1993
DEFINITION Human dynamin mRNA, alternative exons and complete cds.
ACCESSION L07807
VERSION L07807.1
KEYWORDS dynamin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3187)
AUTHORS van der Bliek,A.M., Redelmeier,T.E., Damke,H., Tisdale,E.J.,
Meyerowitz,E.M. and Schmid,S.L.
TITLE Mutations in human dynamin block an intermediate stage in coated
vesicle formation
JOURNAL J. Cell Biol. 122 (3), 553-563 (1993)
PUBMED 8101525
COMMENT Original source text: Homo sapiens (library: Stratagene) brain
(temporal cortex) cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3187
/db_xref="H-InvDB:HIT000191860"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain (temporal cortex)"
/tissue_lib="Stratagene"
CDS 67..2661
/codon_start=1
/product="dynamin"
/protein_id="AAA02803.1"
/translation="MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGK
SSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIE
AETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDML
MQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARD
VLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPY
LQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQ
QFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAI
KNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYP
RLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNK
KKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLS
VDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAG
VYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMP
KTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALS
IIGNINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGP
APGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPE
SPRPPFDL"
exon 1263..1401
/note="see L07808 for alternative exon"
exon 2600..2601
/note="alternative mRNAs have an insert at this point, see
L07809 and L07810"
BASE COUNT 710 a 984 c 900 g 593 t
ORIGIN
1 cgcccggagt cggagccggg agcgctagcg gcagccggat cgcagcctgc ggggcccgcc
61 gcagccatgg gcaaccgcgg catggaagat ctcatcccgc tggtcaaccg gctgcaagac
121 gccttctctg ccatcggcca gaacgcggac ctcgacctgc cgcagatcgc tgtggtgggc
181 ggccagagcg ccggcaagag ctcggtgctc gagaatttcg taggcaggga cttcttgcct
241 cgaggatctg gcattgtcac ccgacgtccc ctggtcttgc agctggtcaa tgcaaccaca
301 gaatatgccg agttcctgca ctgcaaggga aagaaattca ccgacttcga ggaggtgcgc
361 cttgagatcg aggccgagac cgacagggtc accggcacca acaagggcat ctcgccggtg
421 cctatcaacc tccgcgtcta ctcgccgcac gtgctgaacc tgaccctggt ggacctgccc
481 ggaatgacca aggtcccggt gggggaccaa cctcccgaca tcgagttcca gatccgagac
541 atgcttatgc agtttgtcac caaggagaac tgcctcatcc tggccgtgtc ccccgccaac
601 tctgacctgg ccaattctga cgccctcaag gtcgccaagg aggtggaccc ccagggccag
661 cgcaccatcg gggtcatcac caagctggac ctgatggacg agggcacaga tgcccgtgat
721 gtgctggaga acaagctgct ccccctgcgc agaggctaca ttggagtggt gaaccggagc
781 cagaaggaca ttgatggcaa gaaggacatt accgccgcct tggctgctga acgaaagttc
841 ttcctctccc atccatctta tcgccacttg gctgaccgta tgggcacgcc ctacctgcag
901 aaggtcctca atcagcaact gacgaaccac atccgggaca cactgccggg gctgcggaac
961 aagctgcaga gccagctact gtccattgag aaggaggtgg aggaatacaa gaacttccgc
1021 cctgatgacc cagctcgcaa gaccaaggcc ctgctgcaga tggtccagca gtttgccgta
1081 gactttgaga agcgcattga gggctcagga gatcagatcg acacctacga actgtcaggg
1141 ggagcccgca ttaaccgaat cttccacgag cgcttccctt tcgagctggt caagatggag
1201 tttgatgaga aggaactccg aagggagatc agctatgcta tcaagaatat ccatggcatt
1261 agaacggggc tgtttacccc agacatggcc tttgagacca ttgtgaaaaa gcaggtgaag
1321 aagatccgag aaccgtgtct caagtgtgtg gacatggtta tctcggagct aatcagcacc
1381 gttagacagt gcaccaagaa gctccagcag tacccgcggc tacgggagga gatggagcgc
1441 atcgtgacca cccacatccg ggagcgcgag ggccgcacta aggagcaggt catgcttctc
1501 atcgatatcg agctggctta catgaacacc aaccatgagg acttcatagg ctttgccaat
1561 gctcagcaga ggagcaacca gatgaacaag aagaagactt cagggaacca ggatgagatt
1621 ctggtcatcc gcaagggctg gctgactatc aataatattg gcatcatgaa agggggctcc
1681 aaggagtact ggtttgtgct gactgctgag aatctgtcct ggtacaagga tgatgaggag
1741 aaagagaaga aatacatgct gtctgtggac aacctcaagc tgcgggacgt ggagaagggc
1801 tttatgtcga gcaagcatat ctttgccctc tttaacacgg agcagaggaa tgtctacaag
1861 gattatcggc agctggagct agcctgtgag acacaggagg aggtggacag ctggaaggcc
1921 tccttcctga gggctggcgt gtaccctgag cgtgttgggg acaaagagaa agccagcgag
1981 accgaggaga atggctccga cagcttcatg cattccatgg acccacagct ggaacggcaa
2041 gtggagacca tccggaatct tgtggactca tacatggcca ttgtcaacaa gaccgtgagg
2101 gacctcatgc ccaagaccat catgcacctc atgattaaca ataccaagga gttcatcttc
2161 tcggagctgc tggccaacct gtactcgtgt ggggaccaga acacgctgat ggaggagtcg
2221 gcggagcagg cacagcggcg cgacgagatg ctgcgcatgt accacgcact gaaggaggcg
2281 ctcagcatca tcggcaacat caacacgacc accgtcagca cgcccatgcc cccgcccgtg
2341 gacgactcct ggctgcaggt gcagagcgta ccggccggac gcaggtcgcc cacgtccagc
2401 cccacgccgc agcgccgagc ccccgccgtg cccccagccc ggcccgggtc gcggggccct
2461 gctcctgggc ctccgcctgc tgggtccgcc ctgggggggg cgccccccgt gccctccagg
2521 ccgggggctt cccctgaccc tttcggccct ccccctcagg tgccctcgcg ccccaaccgc
2581 gccccgcccg gggtccccag ccgatcgggt caggcaagtc catcccgtcc tgagagcccc
2641 aggcccccct tcgacctcta aacagatccc tcctcttctc ggagacctcc ctttccaagc
2701 ctgcctggac ggctgttctg tgacttgaca gtggctcccc cagccccaaa gccagccccc
2761 ttcatctgtg acttaatctg ttgtagtggt gagctgatac attcaggtgt gaccgttggt
2821 gaaaacttgt gccccttctg tggtatgccc ttgccctgtt ctataaatat ctataaatac
2881 tcatatatat acacacctac acatggccaa ccgcctcgcc tctagcgctg ggaatcagtc
2941 actgtgctat ccttgtggag tcttgtggcc caactaccag agaacgctgt cccccgacat
3001 cccactccaa agtgtgccac ctccagtgag cctccttgtc atgcccggcc tgtggacagc
3061 cagcccccgc catccctccc accccctacc aagcatgggg gtgctgtgca ggcagccgtg
3121 tggcctgaca gtttctacca gtcctgctgt ccctcggctg agaataaaac ccatttctgg
3181 atgatgg
//