LOCUS HUMPPARA 3301 bp mRNA linear HUM 27-APR-1993
DEFINITION Human peroxisome proliferator activated receptor mRNA, complete
cds.
ACCESSION L07592
VERSION L07592.1
KEYWORDS nuclear receptor; peroxisome proliferator-activated receptor;
steroid hormone receptor; steroid receptor superfamily; xenobiotic
responsive element.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3301)
AUTHORS Schmidt,A., Endo,N., Rutledge,S.J., Vogel,R., Shinar,D. and
Rodan,G.A.
TITLE Identification of a new member of the steroid hormone receptor
superfamily that is activated by a peroxisome proliferator and
fatty acids
JOURNAL Mol. Endocrinol. 6 (10), 1634-1641 (1992)
PUBMED 1333051
COMMENT Original source text: Homo sapiens (library: Lambda gt11) cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..3301
/db_xref="H-InvDB:HIT000191843"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="SAOS-2/B10"
/cell_type="osteosarcoma"
/tissue_lib="Lambda gt11"
CDS 338..1663
/standard_name="NucI"
/note="member of steroid hormone receptor superfamily;
putative"
/codon_start=1
/product="peroxisome proliferator activated receptor"
/protein_id="AAA36469.1"
/translation="MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTD
LSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTI
RMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGL
TANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIET
LWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLN
DQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEF
AVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDA
QYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY"
BASE COUNT 705 a 1014 c 879 g 696 t
ORIGIN
1 gaattctgcg gagcctgcgg gacggcggcg ggttggcccg taggcagccg ggacagtgtt
61 gtacagtgtt ttgggcatgc acgtgatact cacacagtgg cttctgctca ccaacagatg
121 aagacagatg caccaacgag ggtctggaat ggtctggagt ggtctggaaa gcagggtcag
181 atacccctgg aaaactgaag cccgtggagc aatgatctct acaggactgc ttcaaggctg
241 atgggaacca ccctgtagag gtccatctgc gttcagaccc agacgatgcc agagctatga
301 ctgggcctgc aggtgtggcg ccgaggggag atcagccatg gagcagccac aggaggaagc
361 ccctgaggtc cgggaagagg aggagaaaga ggaagtggca gaggcagaag gagccccaga
421 gctcaatggg ggaccacagc atgcacttcc ttccagcagc tacacagacc tctcccggag
481 ctcctcgcca ccctcactgc tggaccaact gcagatgggc tgtgacgggg cctcatgcgg
541 cagcctcaac atggagtgcc gggtgtgcgg ggacaaggca tcgggcttcc actacggtgt
601 tcatgcatgt gaggggtgca agggcttctt ccgtcgtacg atccgcatga agctggagta
661 cgagaagtgt gagcgcagct gcaagattca gaagaagaac cgcaacaagt gccagtactg
721 ccgcttccag aagtgcctgg cactgggcat gtcacacaac gctatccgtt ttggtcggat
781 gccggaggct gagaagagga agctggtggc agggctgact gcaaacgagg ggagccagta
841 caacccacag gtggccgacc tgaaggcctt ctccaagcac atctacaatg cctacctgaa
901 aaacttcaac atgaccaaaa agaaggcccg cagcatcctc accggcaaag ccagccacac
961 ggcgcccttt gtgatccacg acatcgagac attgtggcag gcagagaagg ggctggtgtg
1021 gaagcagttg gtgaatggcc tgcctcccta caaggagatc agcgtgcacg tcttctaccg
1081 ctgccagtgc accacagtgg agaccgtgcg ggagctcact gagttcgcca agagcatccc
1141 cagcttcagc agcctcttcc tcaacgacca ggttaccctt ctcaagtatg gcgtgcacga
1201 ggccatcttc gccatgctgg cctctatcgt caacaaggac gggctgctgg tagccaacgg
1261 cagtggcttt gtcacccgtg agttcctgcg cagcctccgc aaacccttca gtgatatcat
1321 tgagcctaag tttgaatttg ctgtcaagtt caacgccctg gaacttgatg acagtgacct
1381 ggccctattc attgcggcca tcattctgtg tggagaccgg ccaggcctca tgaacgttcc
1441 acgggtggag gctatccagg acaccatcct gcgtgccctc gaattccacc tgcaggccaa
1501 ccaccctgat gcccagtacc tcttccccaa gctgctgcag aagatggctg acctgcggca
1561 actggtcacc gagcacgccc agatgatgca gcggatcaag aagaccgaaa ccgagacctc
1621 gctgcaccct ctgctccagg agatctacaa ggacatgtac taacggcggc acccaggcct
1681 ccctgcagac tccaatgggg ccagcactgg aggggcccac ccacatgact tttccattga
1741 ccagctctct tcctgtcttt gttgtctccc tctttctcag ttcctctttc ttttctaatt
1801 cctgttgctc tgtttcttcc tttctgtagg tttctctctt cccttctccc ttctcccttg
1861 ccctcccttt ctctctccta tccccacgtc tgtcctcctt tcttattctg tgagatgttt
1921 tgtattattt caccagcagc atagaacagg acctctgctt ttgcacacct tttccccagg
1981 agcagaagag agtgggcctg ccctctgccc catcattgca cctgcaggct taggtcctca
2041 cttctgtctc ctgtcttcag agcaaaagac ttgagccatc caaagaaaca ctaagctctc
2101 tgggcctggg ttccagggaa ggctaagcat ggcctggact gactgcagcc ccctatagtc
2161 atggggtccc tgctgcaaag gacagtggca gaccccggca gtagagccga gatgcctccc
2221 caagactgtc attgcccctc cgatcgtgag gccacccact gacccaatga tcctctccag
2281 cagcacacct cagccccact gacacccagt gtccttccat cttcacactg gtttgccagg
2341 ccaatgttgc tgatggcccc tccagcacac acacataagc actgaaatca ctttacctgc
2401 aggcaccatg cacctccctt ccctccctga ggcaggtgag aacccagaga gaggggcctg
2461 caggtgagca ggcagggctg ggccaggtct ccggggaggc aggggtcctg caggtcctgg
2521 tgggtcagcc cagcacctcg cccagtggga gcttcccggg ataaactgag cctgttcatt
2581 ctgatgtcca tttgtcccaa tagctctact gccctcccct tcccctttac tcagcccagc
2641 tggccaccta gaagtctccc tgcacagcct ctagtgtccg gggaccttgt gggaccagtc
2701 ccacaccgct ggtccctgcc ctcccctgct cccaggttga ggtgcgctca cctcagagca
2761 gggccaaagc acagctgggc atgccatgtc tgagcggcgc agagccctcc aggcctgcag
2821 gggcaagggg ctggctggag tctcagagca cagaggtagg agaactgggg ttcaagccca
2881 ggcttcctgg gtcctgcctg gtcctccctc ccaaggagcc attctatgtg actctgggtg
2941 gaagtgccca gcccctgcct gacggnnnnn nngatcactc tctgctggca ggattcttcc
3001 cgctccccac ctacccagct gatgggggtt ggggtgcttc tttcagccaa ggctatgaag
3061 ggacagctgc tgggacccac ctcccccctt ccccggccac atgccgcgtc cctgccccca
3121 cccgggtctg gtgctgagga tacagctctt ctcagtgtct gaacaatctc caaaattgaa
3181 atgtatattt ttgctaggag ccccagcttc ctgtgttttt aatataaata gtgtacacag
3241 actgacgaaa ctttaaataa atgggaatta aatatttaaa aaaaaaagcg gccgcgaatt
3301 c
//